2OCE


Conserved Protein Domain Family
S1_Tex
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cd05685: S1_Tex 
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S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression. Tex has two functional domains, an N-terminal domain homologous to the Escherichia coli maltose repression protein, which is a poorly defined transcriptional factor, and a C-terminal S1 RNA-binding domain. Tex is found in prokaryotes, eukaryotes, and archaea.
Links
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Statistics
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PSSM-Id: 240190
Aligned: 28 rows
Threshold Bit Score: 89.5996
Created: 16-Feb-2007
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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RNA binding
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:RNA binding residues of the RNA PolymeraseII RPB7 subunit, confirmed by mutagenesis
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                #       #         # #                                           
2OCE_A       656 GMVLEGVVTNVTNFGAFVDIGVHQDGLVHISalsekfvk----dpyevvkaGDIVKVKVMEVDipRNRVGLS 723  Pseudomonas aeruginosa
NP_060549    919 GTVLTGKVENATLFGIFVDIGVGKSGLIPIRnvteaklsktkkrrslglgpGERVEVQVLNIDipRSRITLD 990  human
NP_971621    645 GMTVKGKIKNVVDFGAFVDLGIKETALLHISemsdsfis----dpleavkvGDIVECKIISLDedRRRISLS 712  Treponema denticola AT...
CAF97071     536 GAVLTGRVDNTALFGAFVDIGVGRSGLIHKSnitpdklpisqrrrslalgpGERVEVRVLNVDhqRGRIGLD 607  Tetraodon nigroviridis
XP_419463    904 GAVLTGKVENATPFGVFVDIGVGKAGLIPVRniteaklskvkkrrslglgpGERVEVKVLNVDipRLRITLD 975  chicken
EAT44396     903 GTVLTGAVNNVTDFGAFVDIGVENNGLIHRSkmngm-----------rvniGDQVEVTVLSIDvgKGRLGLK 963  yellow fever mosquito
ZP_01777601  647 SMRLSGKITNITDFGAFVDLGIKENGLIHKSnlaerfva----hptdivqiNDIVEVEIINIDktRRRIGLR 714  Petrotoga mobilis SJ95
XP_001633298 634 GHELTGRVSNVTTFGAFVDCGIGRDGLIHTSrmagr----------ddlgaGDVVEVKVISKDetKGHVNLQ 695  starlet sea anemone
YP_001256762 644 GMILEGSVQNITDFGIFVYIGIKQAVLIHISkmkktpthyv-ahpkdlvktGDVVTLEIIEINkeNDKIQGK 714  Mycoplasma agalactiae PG2
NP_001014645 915 GEVVTGAVTNVTQFGAFVDVGVERNGLIHNSnmnns-----------qlsvGDRIVASVVKVDlkRRQLELR 975  fruit fly

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