Conserved Protein Domain Family
Bromo_WSTF_like

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cd05505: Bromo_WSTF_like 
Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The Williams-Beuren syndrome deletion transcript 9 is a putative transcriptional regulator. WSTF was found to play a role in vitamin D-mediated transcription as part of two chromatin remodeling complexes, WINAC and WICH. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.
Statistics
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PSSM-Id: 99937
View PSSM: cd05505
Aligned: 4 rows
Threshold Bit Score: 174.262
Threshold Setting Gi: 115952037
Created: 13-Sep-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acetyllysine binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                 #    #  #                                      #   #    
AAL60161      947 EFQKCEEILAKLIKYRFSWPFREPFNADEIEDYTKVVTTPMDFQTMQSKCSCgSYQTVQEFLNDLKLVFGNTELYYEags 1026 African clawe...
AAD08675     1344 ELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCgSYRSVQEFLTDMKQVFTNAEVYNCrgs 1423 human
XP_001188851  507 DKEAADGIISRMLKYRDSKPLRQPPTKAEVPNYKKLIKNPMDLQVMKTKCEGkDYSKYPEFFDDMQLTFSNAAKMYEndn 586  Strongylocent...
CAM13000     1371 ELQKCEEILQKIMKFRHSWPFREPVSAEEAEDYQDVITSPMDLTTMQGKFKSsEYHSASDFIEDMKLIFSNAEEYNQpss 1450 zebrafish
Feature 1          #               
AAL60161     1027 SQLSCLEKTEQCARDLL 1043 African clawed frog
AAD08675     1424 HVLSCMVKTEQCLVALL 1440 human
XP_001188851  587 YILQQVRKTKDYCGNLI 603  Strongylocentrotus purpuratus
CAM13000     1451 NVLTCMSRTEEAFVELL 1467 zebrafish

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