Conserved Protein Domain Family
Bromodomain_1

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cd05494: Bromodomain_1 
Bromodomain; uncharacterized subfamily. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
Statistics
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PSSM-Id: 99926
View PSSM: cd05494
Aligned: 10 rows
Threshold Bit Score: 78.6398
Threshold Setting Gi: 74181165
Created: 16-Sep-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_932535     139 DDEELKRVLRSLQMrah-------------kmAQPFLEPVDP-------------------NDAPDYYGVIKEPVAAAAP 186  human
XP_394969     881 IYEKEEISLRELRIflreica----klarnrqFFMFTKPVDT-------------------EEVPDYIYVVCKSININNK 937  honey bee
XP_368320     327 LYEAAEKVLSELKAht--------------eySTPFLSRVNK-------------------RDAPDYYNRRKLRSSFHSS 373  Magnaporthe g...
CAN68216      889 DKEELKAALVVIKKvmk------------mdaAEPFNVPVNPv-----------------eLGIPDYFDVIDTPMDFGTI 939  wine grape
CAF98873      725 DYTALYKVLEALKShk---------------dAWPFLEPVDE-------------------SYAPNYHDIIKHRMVDGRH 770  Tetraodon nig...
AAG50696      212 NKQELEDSLIVIKKimk------------meaADPFNVPVNPe-----------------aLGIPDYFDIIKTPMDFGTI 262  thale cress
EAZ41783      235 YKEALSWFEQECQRle---------------pPMPLALPPPPqppvpmpmqappriggggrRPKPKAREPNKREMSDEEK 299  Japanese rice
XP_529035      54 DGAAGQRCSSPPRRgrgraevlltsqagrhgrGAPHISDDGRpgr--------------daSHFLDGMAAGKRRSSLPRW 119  chimpanzee
BAE27845     1344 NLEEMEEEVRLKKRkrrr-----------nvdKDPVKEDVEKak---------------krRGRPPAEKLSPNPPKLTKQ 1397 house mouse
XP_001333071 1065 DLTYCEIILMEMEAhs---------------dAWPFLEPVNP-------------------RMVPGYRRIIKNPMDFLTM 1110 zebrafish
XP_932535     187 QQSIPWt------------EMASQDLEQSCRKLPSLMLEESRTNMWTRkkktsgvsev------------qavhlvqpvp 242  human
XP_394969     938 VKVHTDihvvcfhvslrdrPSLGILKRDPADKLIRHRACSLRDNAYALika--------------------------eld 991  honey bee
XP_368320     374 PNIIVRpraev----eaeeRRKQNGGEDDAGDDSDDEPIMSSRGRIAGskgtn----------------------ksrka 427  Magnaporthe g...
CAN68216      940 CDNLEKdaape---qdsvlEGLPPEGPSVRDKAIVATGRKTDMLASKEeivetssingfgs------iqaedfvpssqgk 1010 wine grape
CAF98873      771 VGPRYPm-----------gHDPNHQQPQHQQQPPYMGPTHGPSLGPRPmalqpg--------------------pppeas 819  Tetraodon nig...
AAG50696      263 CNNFEK-------------GNKYMNSEDVYKDVNYIWNNCSKYNKKGDy------------------------------- 298  thale cress
EAZ41783      300 HKLRVEignlp---eekmgNVLQIVQKRNTDPALMGEVVELDFDEMDVetl--------------------------wel 350  Japanese rice
XP_529035     120 DGGQVEt-----------lLTFQSGQPGRGAPQIPDDGRPGPESQYTKta----------------------------qe 160  chimpanzee
BAE27845     1398 MNAIIDtvi--------nyKDRCNVEKVPCNSQLEIEGNRSESVIISIgawetwrktscfsvtthrhstwkdprstktpl 1469 house mouse
XP_001333071 1111 RERLLQggd-------ialSHTLKMAEVKQQETEDMIVTRDCQSILAVls----------------------------ti 1155 zebrafish
XP_932535     243 IHQQGHQPDARAQHVH 258  human
XP_394969     992 SDFEDKCREISKNRRI 1007 honey bee
XP_368320     428 PSDQQEQAPGTDTKPV 443  Magnaporthe grisea 70-15
CAN68216     1011 IHIKSSQLKNKKQKRH 1026 wine grape
CAF98873      820 MYPSHHHPEGLNMHHM 835  Tetraodon nigroviridis
AAG50696      299 IVDLMKRVKKNFMKYW 314  thale cress
EAZ41783      351 DRFVVNCKKALSKSRR 366  Japanese rice
XP_529035     161 IVNVCYQTLTEYDEHL 176  chimpanzee
BAE27845     1470 SYSQCLRVLGRKLPKK 1485 house mouse
XP_001333071 1156 VFVNLKGMFMQCRDLP 1171 zebrafish
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