Conserved Protein Domain Family
SIS_RpiR
?
cd05013: SIS_RpiR 
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Links
?
Statistics
?
PSSM-Id: 240144
Aligned: 395 rows
Threshold Bit Score: 61.8612
Created: 28-Mar-2007
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
 
putative active
Feature 1:putative active site [active site]
Evidence:
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                  #                                                #    
CAA57687     129 DEIHRAARFFYqa-rqRDLYGAGG--SNAICADVQHKFLRIGv-----rCQAYPDAHIMMmsasllqeGDVVLVVTHSGr 200 Escherichia coli
YP_001373014 119 DDFEAAIDAAAdlnmrVHCLGGRF--SGFLAGLLWSHMKQLRgetrwinGTQADQVDWLVdl----gkRDVLFVYDYRRy 192 Ochrobactrum an...
YP_674430    123 SDFDRARDLLReqrnhVYIVGGRI--TKSLAEYLFTHCQVIRpnvtliaPTPSTWPHYALnm----rsGDVLVIFDIRRy 196 Mesorhizobium s...
YP_682459    124 AGFDEACALVAdparhLYIVGGRI--THTMAEYLFLHMQVIRpnlthvqSTSNTWPHYLLna----gkGDVFVIFDVRRy 197 Roseobacter den...
YP_161925    134 CELEDVTELLAdcsrnVYIVGNHL--THPIAELFWYQLHRLRprt-hlvQNNAFTPYEQLids---grRDILLLFDICHy 207 Zymomonas mobil...
ZP_01129568  128 TEIIEIAKLIAnprnrIWTVGGRF--SDLLAQYLTLHLRLLRkd---vnHVDPTEQEKAFtlld-ftsRDVLIAFDYRRy 201 marine actinoba...
ZP_00995686  120 ADIDAAVALLSdpkrrVCVLGGRY--SGFIARYLAFHLQQVRpgv-stlDDAMNTGSSLAida---rrRDVAVIFDLRRy 193 Janibacter sp. ...
EAY66774     123 AAFDAAVAVLAdp--dVRVFCGGGryTAPLASLFSFTLAYARph---vqYVEPNVNLASValad-mgrNDVLVIFDFRRy 196 Burkholderia ce...
YP_347791    119 EDVRILADWLLdtrhqVYCFGGRF--SSLMATYLLNHLRLLRpgc--faLEDNAQLPDRLfdl---qrQDVVLVFDYRRy 191 Pseudomonas flu...
NP_693631    116 DVLNDVIERILds-ekVIVAGYYH--SFSFAHWFSFNLNYIVgna--slFRPESDAGILElm----pkKSCIIIFSFFRy 186 Oceanobacillus ...

Feature 1                                                                           
CAA57687     201 tsdVKAAVELAKkngakIICIThsyhspiaklADYIICSpapetpllgrnaSARILQLTLLDAFFVS 267 Escherichia coli
YP_001373014 193 qidTIRFARQAAkqgarIVLFTdrwvspiaefASVTLTAavdt----vspyDTMVPAIAQTEALIAG 255 Ochrobactrum anthropi ATCC 4...
YP_674430    197 ereIETLSRIAAerglhTILFTdrwkspvaktATVVFRVetev----psawDSSVVMLFVVEALIEA 259 Mesorhizobium sp. BNC1
YP_682459    198 ennTLKLAELAHargakIVLFTdqwrspvhplADITLSSrivv----psawDSAATTLLLVETLIAA 260 Roseobacter denitrificans OC...
YP_161925    208 qedIALLAEQAHqrrttIILITdpklspvsrlAHHVLTCdftl----ftshESLVPCLVMVELLAAS 270 Zymomonas mobilis subsp. mob...
ZP_01129568  202 qggTVSFLKNAKnkkatTVLFTdpwlspaakhADYLLSSsvts----pspfDSLTSGFALVETVIAG 264 marine actinobacterium PHSC20C1
ZP_00995686  194 qssTVEAAVALSakgttIICVTdewlspvadvATVTLTTsvas----vgpfDSAAAAFVLAELLVDG 256 Janibacter sp. HTCC2649
EAY66774     197 qkdSIRFAQAAHqlgarILLITdewrspigefAEIVLRIqgrp----famlQTNVPALALAEALVIG 259 Burkholderia cenocepacia PC184
YP_347791    192 qtqALRVASAAKnsnarVVLFTdiyasplrelADMIISApves----aspfDTMVPALAQVEALIAC 254 Pseudomonas fluorescens PfO-1
NP_693631    187 aidTIRLAEEAKkkgvpVIVITdswaspaaeyADFVISIyssdn--snvllQKGPITMSLMNSILSK 251 Oceanobacillus iheyensis HTE831

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap