Conserved Protein Domain Family
ACT_AKiii-DAPDC_1

?
cd04935: ACT_AKiii-DAPDC_1 
ACT domains of a bifunctional AKIII (LysC)-like aspartokinase/meso-diaminopimelate decarboxylase (DAPDC) bacterial protein
This CD includes the first of two ACT domains of a bifunctional AKIII (LysC)-like aspartokinase/meso-diaminopimelate decarboxylase (DAPDC) bacterial protein. Aspartokinase (AK) is the first enzyme in the aspartate metabolic pathway and catalyzes the conversion of aspartate and ATP to aspartylphosphate and ADP. The lysA gene encodes the enzyme DAPDC, a pyridoxal-5'-phosphate (PLP)-dependent enzyme which catalyzes the final step in the lysine biosynthetic pathway converting meso-diaminopimelic acid (DAP) to l-lysine. Tandem ACT domains are positioned centrally with the AK catalytic domain N-terminal and the DAPDC domains C-terminal. Members of this CD belong to the superfamily of ACT regulatory domains.
Statistics
?
PSSM-Id: 153207
View PSSM: cd04935
Aligned: 5 rows
Threshold Bit Score: 130.711
Threshold Setting Gi: 114568958
Created: 2-Apr-2007
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
ZP_00952864 325 VRIVAMEGAGMWRQAGFLADVFACFKECGVSVDLVSTSETNVTVSLDPDp-sLDQARLDALRARLERFCRVKIMD 398 Oceanicaulis alexandr...
ZP_00681627 322 IVLVSMEGIGMWQQVGFLADVFTLFKKHGLSVDLIGSAETNVTVSLDPSenlVNTDVLTALSTDLSQICKVKIIV 396 Xylella fastidiosa Ann-1
YP_444447   326 ITAVSMDTLGMWQEVGFLADVFQVFKHHGLSVDLMATSESNVTVTLDPVanaLDPDILDRLLHDLNRYCDAELID 400 Salinibacter ruber DS...
YP_755638   317 VRLITLETDGMWRASGFLSKAFEPFARHGVSIDLVSTSETSVTVSLDDDp-gLTPDVLGALEDDLAQIARVEIIE 390 Maricaulis maris MCS10
YP_124092   321 ILLISIDTLNMWQQVGFLADVFAAFKKHGFSVDLLSSSEFNVTLSLDVNakiHDRPAINALLDDLNQFGRAKLIE 395 Legionella pneumophil...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap