Conserved Protein Domain Family
ACT_AK-LysC-DapG-like_1

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cd04891: ACT_AK-LysC-DapG-like_1 
ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins
This CD includes the N-terminal of the two ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168, and the lysine plus threonine-sensitive aspartokinase of Corynebacterium glutamicum, as well as, the first and third, of four, ACT domains present in cyanobacteria AK. Also included are the N-terminal of the two ACT domains of the diaminopimelate-sensitive aspartokinase isoenzyme AKI found in Bacilli (Bacillus subtilis strain 168), Clostridia, and Actinobacteria bacterial species. Members of this CD belong to the superfamily of ACT regulatory domains.
Statistics
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PSSM-Id: 153163
Aligned: 88 rows
Threshold Bit Score: 38.3069
Created: 27-Mar-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_104539   273 AQISLRRVgd--rPGVAAGIFGPLAeaNINVDMIVQNIsedgkfTDMTFTVPsg---dvDKALAVLD 334 Mesorhizobium loti MAFF303099
AAD36585    262 IKVSISFLpk--dVKYITAIFEEVGkrALNVDMISLVPsn--gkVFLSFTILedhkedlDEALKEAL 324 Thermotoga maritima MSB8
YP_040807   262 MHVTISYPlp--dNQLLTQLFTELEegAVNVDMISQIVnl--dgLQLSFTIKds---dfHQISMILK 321 Staphylococcus aureus subsp. ...
ABB15023    276 TQIKILREdtpeiVNLAQKVFKGLAlaEISVDFINISP------EGLAFTVKge---vtEKAVDVLE 333 Carboxydothermus hydrogenofor...
NP_470811   272 TQIFVKTDt----VKAQQQTFKILAdaGISLDFINIST------DSVIFTVPee---krRVVKQLLE 325 Listeria innocua Clip11262
BAB81384    267 IQVSIKSDdn-kdNINYKTILESLAnnKISLDLINIFP------KEKVFTIDag---vkELFEDIMR 323 Clostridium perfringens str. 13
NP_781912   266 TQIKIELEqn-keNESYFRILDILAenSISIDLINVFP------RESIFTIDgk---dfEKFSSIMN 322 Clostridium tetani E88
AAK79775    267 VQVTTKFKd---sKIKSTEFLSLLGerNINIDLINVFP------KENIFTIDkk---dlNKLKDTLI 321 Clostridium acetobutylicum AT...
GAA02267    307 TQFRIPMDgcgdtAGLQRRMFEALAlaGISIDFINVHP------DVVIFTVKns---vaAKAAQILE 364 Pelotomaculum thermopropionic...
ZP_01147878 273 TQLKIIAKdi-avEDPALRIFRALAlaDISIDFINVSP------ELIMLTVKde---vaKKAVDVLE 329 Desulfotomaculum reducens MI-1
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