Conserved Protein Domain Family
ACT_PheB-BS

?
cd04888: ACT_PheB-BS 
C-terminal ACT domain of a small (~147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains
This CD includes the C-terminal ACT domain of a small (~147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and other related ACT domains. In B. subtilis, the upstream gene of pheB, pheA encodes prephenate dehydratase (PDT). The presumed product of the pheB gene is chorismate mutase (CM). The deduced product of the B. subtilis pheB gene, however, has no significant homology to the CM portion of the bifunctional CM-PDT of Escherichia coli. The presence of an ACT domain lends support to the prediction that these proteins function as a phenylalanine-binding regulatory protein. Members of this CD belong to the superfamily of ACT regulatory domains.
Statistics
?
PSSM-Id: 153160
View PSSM: cd04888
Aligned: 18 rows
Threshold Bit Score: 94.9529
Threshold Setting Gi: 62286997
Created: 24-Aug-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q5HNQ8       73 FTLILYVNDIVGMLAQVLNAISqLQLSVLTIHQSVPIEDKATITLSLNARnSNLSIDEVIESLReINHVTKVDLIS 148 Staphylococcus epide...
BAB04933     69 ITLSINLEDRSGSLSAMLATVAeAEANVLTINQTIPLQGRANITLSIDTAtMSLEIDELVEKIEsMEAVEKVELVG 144 Bacillus halodurans ...
NP_390669    69 ITLFFHLEDRSGALSQLLQAVAdSGSNVLSIHQTIPLQGRANVTLSISTSaMEEDIHTLMNKLRkFDFVEKVEILG 144 Bacillus subtilis su...
AAM25741     70 ITFSMVLEHMPGVLSSILDVVAkERGNVVTINQSIPSMGVASVTISIDTQyMEISIEDFIEELSkQPGVRKIEVLG 145 Thermoanaerobacter t...
BAB81120     68 VIFNMVVTHEKGVLSSVLNILSdVGGNILTIDQGLPIHGLAHVSFTIDIStMKCDIKEMLNEIElVHGVEKVEFVA 143 Clostridium perfring...
AAK79206     78 VTISILIEHRRGTLSEVLDKLAqRCCNILTINQDIPINNTANVNITFDISgISGDVKNIVEELKkIKNVLKVEIVA 153 Clostridium acetobut...
ZP_01725860  22 LTVFLQLQDRKGTLAKLLETVTiTHCNVLTIHQTIPIQGRANVTLSLDVTsMTCDLDDLIQQLKrLDFVESAEVIS 97  Bacillus sp. B14905
ZP_01361398  69 VTLSFLLSHQAGVLSNVLHIISvNNGNILTINQDSPINNFANVNIIFDITeISKKLDDIIQEIEsIDGVEKLEILA 144 Clostridium sp. OhILAs
YP_806282    67 AVISLMLHHDRGILSEVLTTMSqVQASIVTINQNIPIHNWASVVMSFDISaLQGTLDDLVTKLGdIRGVSDVHLVS 142 Lactobacillus casei ...
YP_619210    67 AVLSLLLADLPGALSAVLTCVTdHRASVLTISQAIPLASHASVLMSLDLAgLKGDINTLLADLKsLPFVKNLQLAG 142 Lactobacillus delbru...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap