Conserved Protein Domain Family
otoconin_90

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cd04707: otoconin_90 
otoconin_90: Phospholipase A2-like domains present in otoconin-90 and otoconin-95, mammal proteins that are principal matrix proteins of calcitic otoconia. Interactions involving otoconin-90 may trigger or constitute key events in otoconia formation. The PLA2-like domains in otoconins may have lost their metal-binding sites.
Statistics
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PSSM-Id: 153096
View PSSM: cd04707
Aligned: 6 rows
Threshold Bit Score: 140.304
Threshold Setting Gi: 47209354
Created: 3-Jan-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:putative catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                  #                                     
Q02509       323 QLGEMLFCLTSRCPEEFESYGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRLGClle-rlpWSPVVCVDHtPKCGGQSL 401  human
NP_001028816 352 QLGEMLFCLTERCPEEFESYGCYCGQEGRGHPTDALDRCCFSHHCCVEQVKTLGCpae-rssRSEVVCFDHmPKCIGWSL 430  chicken
CAF94892      17 SLGEMLHCLTGRCPHEYEMYGCYCGQQGGGQPVDQLDRCCFFHGCCLSQISAMGCrqd-rklHAHLTCQHGrPGCQGVSV 95   Tetraodon nigr...
AAX37320     739 ALGEMLHCLTGRCPHEYQHYGCYCGQQGTGQPVDRLDRCCFLQQCCLEQLSVFGCrtn-rklNAHISCHKAkPQCFGVSV 817  zebrafish
NP_001028816  80 NFVNKMKCVSGFCPRDFEDYGCSCRFEMEGLPVDEADECCFQHRKCYEEAMEMECtwdpskiSTDVTCSAEnLSCENGDP 159  chicken
Q02509        78 QFVNGMKCVAGLCPRDFEDYGCTCRFEMEGLPVDESDSCCFQHRRCCEEAAEMDClqdpaklSTEVDCVGKkIICESKDN 157  human
Feature 1                #                             
Q02509       402 CEKLLCACDQTAAECMTSASFNQSLKspsrlgCPGQPA 439  human
NP_001028816 431 CEKLLCACDQTAAQCMASALFNESLKfphgqvCQEEKA 468  chicken
CAF94892      96 CDKLQCVCDKTTAQCMAAARFNHSLTah---qCAGPAP 130  Tetraodon nigroviridis
AAX37320     818 CDRLQCVCDRSTAECMAASHFNSSASs----sCSGPRP 851  zebrafish
NP_001028816 160 CEQFLCTCDKDAIECFGNAHINSSLNgldvssCPSLVT 197  chicken
Q02509       158 CEHLLCTCDKAAIECLARSSLNSSLNlldtsfCLAQTP 195  human

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