PolII_SU_OBF: A subfamily of OB folds corresponding to the OB fold found in Pyrococcus abyssi DNA polymerase II (PolII) small subunit. PolII is a family D DNA polymerase, having a 3-prime to 5-prime exonuclease activity. P. abyssi PolII is heterodimeric. The large subunit appears to be the polymerase, and the small subunit may be the exonuclease. The small subunit contains a calcineurin-like phosphatase superfamily domain C-terminal to this OB-fold domain.
Comment:Based on similarity to various OB folds with structures.
Comment:The generic binding surface I contains nucleic acid partners in most OB-fold complexes. In some cases, this surface may also contain the sites for protein-protein interaction.
Jiyao W et al.(2023). "The conserved domain database in 2023.",