Conserved Protein Domain Family
S1_RNase_R
?
cd04471: S1_RNase_R 
S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase play an important role in the degradation of RNA with extensive secondary structure, such as rRNA, tRNA, and certain mRNA which contains repetitive extragenic palindromic sequences. The C-terminal S1 domain binds ssRNA.
Links
?
Statistics
?
PSSM-Id: 239917
Aligned: 100 rows
Threshold Bit Score: 76.2853
Created: 14-Jun-2006
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
 
RNA binding
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:RNA binding residues of the RNA PolymeraseII RPB7 subunit, confirmed by mutagenesis
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                #       #          # #                                                 
P21499      643 VGNVFKGVISSVTGFGFFVRLddlfIDGLVHvssLDNDYYRFDqvgqrLMGeSSGQTYRLGDRVEVRVEAVNMDERKIDF 722 Escherichia coli...
CAF27614    643 IGCTFTGRVSGVTKAGLFISLdtlnIDGFVHistLKNDYYYFDevqhtLVGkRSHKGYQLTDIVKVKLIKVQPFAGALCF 722 Bartonella hense...
BAB48344    652 IDDRFDARISGVTKSGLFVQLpqygADGFIPvstLGGDYYIYDeaarsLFGeRTGKGYQLADHVEVRLVEVAPMAGAMRF 731 Mesorhizobium lo...
ZP_01012492 627 VGNEMTGRIAGVQRFGIFVRLdetgADGLVPvssIGAEYFRYEepsqsLVGeRSGLELTVGLPVLVRLSEAVPVTGGLMF 706 Rhodobacterales ...
NP_421256   639 VGATFEGRITGVTRFGLFIKLadtgADGLVPvssLGQEFFVHDdkmhaLVGeRTGKRWPLGLSVEVKLVEATPVTGGLLF 718 Caulobacter cres...
YP_458112   625 VGKTFQTRITGVQNFGFFATIlnlgGDGLVPvstLGREYYRYDeaaqaLVGeDSGKRYDVAQKLELKLAEANPLTGALKF 704 Erythrobacter li...
YP_760975   624 VGAEFDGRITGVTPAGLFVALagsgADGFVPissISEDYWIHDeaavaVYArGSGKTFSIGQIVRVRLREVTPLQGGLLL 703 Hyphomonas neptu...
YP_616279   643 VGEIVAARITGVQPFGFFATVdglgGDGLVPvstLGSERFFYDeaartLDSeHGRVSFSVGQRLDLRLVDANPVSGALRF 722 Sphingopyxis ala...
YP_744624   694 VGARFAARISGVTRFGLFITVeengASGIVPissLPDDFWIHDereqaLIGrNSRAVWRLAQSVTVRLAEATPITGGLVF 773 Granulibacter be...
NP_975826   624 INTTYTATISAVLKFGIFIQLdn-lVEGLVHi-sNMNSDLVYDetnriLIK-PDNTYYRIGQKVKVKLISVDIKKRTIDF 700 Mycoplasma mycoi...

Feature 1          
P21499      723 SLI 725 Escherichia coli K12
CAF27614    723 ELL 725 Bartonella henselae str. Houston-1
BAB48344    732 EML 734 Mesorhizobium loti MAFF303099
ZP_01012492 707 QLL 709 Rhodobacterales bacterium HTCC2654
NP_421256   719 EML 721 Caulobacter crescentus CB15
YP_458112   705 EPL 707 Erythrobacter litoralis HTCC2594
YP_760975   704 EML 706 Hyphomonas neptunium ATCC 15444
YP_616279   723 ELP 725 Sphingopyxis alaskensis RB2256
YP_744624   774 NLL 776 Granulibacter bethesdensis CGDNIH1
NP_975826   701 VLI 703 Mycoplasma mycoides subsp. mycoides SC str. PG1

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap