Conserved Protein Domain Family
DEP_fRgd2
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cd04436: DEP_fRgd2 
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGAP (GTPase-activator protein) Rgd2-like proteins. Rgd2-like proteins share a common domain architecture, containing, beside the RhoGAP domain, a DEP and a FCH (Fes/CIP4 homology) domain. Yeast Rgd2 is a GAP protein for Cdc42 and Rho5.
Links
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Statistics
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PSSM-Id: 239883
Aligned: 9 rows
Threshold Bit Score: 141.325
Created: 18-Sep-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_503587 234 ELGNLMKKALQDIKRADlKVAILGTYe-NVSSGDQIVSWIQQNVpipsdssaVAFAERFGQDLVTQGYLRLVGQVGSKFA 312  Yarrowia lipolyti...
1175379   205 ELKEVLAQVLQEIPLQDyRVPILGTYp-NTCSGNIIVSWLQENLpv----ptLVAAEAFGQDLIAQGFLRHMGVGGSFVN 279  fission yeast
XP_500942 215 ALKMIFTDMLKEIPLKSlKVPILGTYk-RISTGDQIVMWLRKNMdm----psIAAAEKFGQDLLAQGYIRLVGQVGNRFG 289  Yarrowia lipolyti...
NP_983190 199 SARELVHALLTRLEKHEyRVPLINYVfqGTNNGSEIARFLFEYMsl----ddLDEAEAAGQDLLNKGFLKYCNGVGGGFV 274  Eremothecium goss...
1175952   205 TMKETLQLLLTKLPKTDyKLPLISYSlsNTNNGGEITKFLLDHMsl----kdIDQAETFGQDLLNLGFLKYCNGVGNTFV 280  baker's yeast
CAG87626  203 SVKALLTSILKNIELAShKVPILGTYn-NVSSGSAITQWLLDNMnel--nrnIAKAEIFGQDLVNSGFIRLIGSMSSGKN 279  Debaryomyces hans...
CAE76173  206 QIKKILAHMLNNIKMGEtKVPILGTYq-NTSAGTDIVEYLQRHMgt----tsISYAERIGQDLITHGFLRLIGNVGNTFA 280  Neurospora crassa
XP_710399 212 QMKALLKAMLTEVPMGPhKVAILGTYq-NVSTGSNITKWLLENMpef--nknLDKAEVFGQDLVRNDFIRIVGSMGKSFI 288  Candida albicans ...
CAG61740  226 STREIIIALLKDLPKSEfRVPLINYTlnNTNSGREITDFLKTALsi----kdLDEAEAFGQELLNLGFIKYCNGVGTTFV 301  Candida glabrata ...

XP_503587 313 NSsaFSYQW 321  Yarrowia lipolytica CLIB122
1175379   280 STnfHYQWK 288  fission yeast
XP_500942 290 NAssLNYQW 298  Yarrowia lipolytica CLIB122
NP_983190 275 NSkkFQYQW 283  Eremothecium gossypii
1175952   281 NSkkFQYQW 289  baker's yeast
CAG87626  280 FInsSQFFY 288  Debaryomyces hansenii CBS767
CAE76173  281 NSsrMSYQW 289  Neurospora crassa
XP_710399 289 NSsqFYYQW 297  Candida albicans SC5314
CAG61740  302 NSkkFQYQW 310  Candida glabrata CBS 138
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