1GO3


Conserved Protein Domain Family
RNAP_E_N
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cd04331: RNAP_E_N 
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RNAP_E_N: RpoE, N-terminal ribonucleoprotein (RNP) domain. RpoE (subunit E) is a subunit of the archaeal RNA polymerase (RNAP) that is homologous to Rpb7 of eukaryotic RNAP II, Rpc25 of eukaryotic RNAP III, and Rpa43 of eukaryotic RNAP I. RpoE heterodimerizes with RpoF, another RNA polymerase subunit. RpoE has an elongated two-domain structure that includes an N-terminal RNP domain and a C-terminal oligonucleotide-binding (OB) domain. Both domains of RpoE bind single-stranded RNA.
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Statistics
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PSSM-Id: 239823
Aligned: 22 rows
Threshold Bit Score: 91.5007
Created: 11-Aug-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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RpoF
Conserved site includes 13 residues -Click on image for an interactive view with Cn3D
Feature 1:RpoF interaction site [polypeptide binding site]
Evidence:
  • Structure:1GO3_MN; Methanocaldococcus jannaschii RpoE N-terminal RNP domain binds RpoF; defined using 3.5A contacts.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1       ##### # #                       ##              #     ##                        
1GO3_M        2 YKILEIADVVKVPPeeFGKDLKETVKKILMEKYEGRLd--------kDVGF--VLSIVDVKDIGEGKVvhGDGSAYHPVV 71  Methanocaldococc...
CAJ37170      2 YRKVRLVDIIRIPPqrLEEDLEKVISETLREKLEGRId--------kTLGS--IVAVTDVVEIGEGHIlvGDGAVYYEVT 71  uncultured metha...
ZP_01391131   2 YYKMTLEDKVRVPPhrLGEDLEKVILNVLQEQLEGSIa--------kEIGI--FIAVTNILNVGEGELipGDGAVYYDVR 71  Methanoculleus m...
NP_618567     2 YKLMKLIDTVRIPPtlLGEEIMPTIKNALREKLEGQVd--------kKLGS--LVAVYNIDEVGEGHIlvGDGAVYYDVT 71  Methanosarcina a...
AAB90126      2 YARIKLRDTVRVPPskLGEDIEKVINSLLWEQFEGRLd--------rEYGM--IIGIESIEEIGEGRIieGDGGVYFDVV 71  Archaeoglobus fu...
EAM94489      2 YILLEDEYVIRVPPelLNDNYSDAVAEASKSTLEGKLvdiq--egqkNIGKsyIVSVNSIEMKGEGTIvhGDGGVYQSIK 79  Ferroplasma acid...
NP_394548     2 YMLVEDKYIARVPPemLGEDYDVAVREVTKRSLEGRLvdvinektsqNEGKylVISVLYTESIGEGTIvhGDGGVYQEVK 81  Thermoplasma aci...
AAG20209      2 YKRARLKDTIEVPPeyLGAVGPDLVKRLLQDKLEGRMd--------eDVGS--IVTVTEVHDLGEGAVlpNRPGVYYEAE 71  Halobacterium sp...
AAT43451      2 YISLENDYVARVPPelLGDDYREAVLEITKRNLVGKLvdind-stgrNMGKcfIVSIENIELVGDGTIvhGDGGVYQDVV 80  Picrophilus torr...
YP_843739     2 YKRMKLEGVVRIPPedMGNPLNDAVEMALRNKYEARVd--------rTLGA--IVAILGVDSIGEGRIiaGDGAVYYDVI 71  Methanosaeta the...

Feature 1               # 
1GO3_M       72 FETLVYIPEM 81  Methanocaldococcus jannaschii
CAJ37170     72 FDAIAYKPEQ 81  uncultured methanogenic archaeon
ZP_01391131  72 FEAAVLRLAL 81  Methanoculleus marisnigri JR1
NP_618567    72 FEAIMFIPEL 81  Methanosarcina acetivorans C2A
AAB90126     72 FNAICFRPLH 81  Archaeoglobus fulgidus DSM 4304
EAM94489     80 YSALAYFPKM 89  Ferroplasma acidarmanus Fer1
NP_394548    82 YRALVYYPEM 91  Thermoplasma acidophilum DSM 1728
AAG20209     72 FDAVTFEPEM 81  Halobacterium sp. NRC-1
AAT43451     81 YTAIAYYPKM 90  Picrophilus torridus DSM 9790
YP_843739    72 FDAVVFKPEM 81  Methanosaeta thermophila PT

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