Conserved Protein Domain Family
DUF619-NAGS-FABP

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cd04266: DUF619-NAGS-FABP 
DUF619 domain of N-acetylglutamate Synthase of the fungal arginine-biosynthetic pathway
DUF619-NAGS-FABP: This family includes the DUF619 domain of N-acetylglutamate synthase (NAGS) of the fungal arginine-biosynthetic pathway (FABP). This NAGS (also known as arginine-requiring protein 2 or ARG2) consists of an N-terminal NAG kinase-like domain and a C-terminal DUF619 domain. NAGS catalyzes the formation of NAG from acetylcoenzyme A and L-glutamate. The DUF619 domain, yet to be characterized, is predicted to function in NAGS association in fungi.
Statistics
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PSSM-Id: 176268
View PSSM: cd04266
Aligned: 6 rows
Threshold Bit Score: 186.508
Threshold Setting Gi: 498995
Created: 2-Dec-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAA84051 423 HDYIKRINGKIATIIVIGDYEGIAILTYEgse-----------ensFVYLDKFAVLphlkgslGISDIIFNLMfk----- 486 baker's yeast
AAW42706 383 EGFYNRLKNDLDFVIVIGDYAGAAVCTLEgkpvsdsfayppnhpepICYLDKFAVHpsh-qgdGTVDFLWVALrdetygl 461 Cryptococcus neofor...
AAT07967 458 KKYLARVKNNVAAILIAGDYEGVIIVTWEvtdee--------kpqkIAYLDKFAVSpkaqgstGVADVLFKSLls----- 524 Pichia pastoris
AAC37502 565 EHYLDRVKDSLAGIIIAGEYEGGAILTWEtpfgldee-tayrkgrlVPYLDKFAVLrksqgagGVADIVFNAMvr----- 638 Neurospora crassa
CAG84481 429 EKYFDRINDSLATVVIVGDYDGAAIITWEtcsk---------tnekIAYLDKFAIAsvnqglpGLADIIFKIIlq----- 494 Debaryomyces hansenii
CAA22186 367 DAYLDRLKNSLAAVIIAGDYLGTAIVTYEqpdgt--------tnekVPYLDKLAVSqgaqgsaAISDVMFNVMtd----- 433 fission yeast
CAA84051 487 ----------------kFPNEILWRSRKDNVVNKWYFQRSVAVLDlsidldpehcdekqsqFKLFYYG 538 baker's yeast
AAW42706 462 gqldasnpsigslrgvgRGRDLVWRSRSDNPVNKWYYERSSGFLKtrd-----------ekWKVFWCD 518 Cryptococcus neoformans var. ne...
AAT07967 525 ----------------nFENELFWRSRSNNPVNKWYFERSKGSLTvtg-----------tnWKCFYTG 565 Pichia pastoris
AAC37502 639 ---------------daFPDGVCWRSRKDNPVNKWYFERSRGVLKlpe-----------snWAMFWTT 680 Neurospora crassa
CAG84481 495 ----------------sHPNELIWRSRKNNPVNKWYFERCCGTLSnpg-----------sqWKIFYTG 535 Debaryomyces hansenii
CAA22186 434 ----------------lFPKELIWRSRLTNPVNKWYFERSVGSLKssk-----------tpWKLFWTG 474 fission yeast
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