1RCY,1A3Z,1A8Z,2CAK


Conserved Protein Domain Family
Rusticyanin

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cd04231: Rusticyanin 
Click on image for an interactive view with Cn3D
Rusticyanin is a cupredoxin in archaea and proteobacteria
Rusticyanin is a copper-containing protein which is involved in electron-transfer. The members of this family are found in archaea and proteobacteria. It is a cupredoxin, or blue-copper protein due to its color. Rusticyanin, extracted from the bacteria Thiobacillus ferrooxidans is redox active down to PH 2.0 and the acid-stable cytochrome c is the primary acceptor of the electron. This organism can grow on Fe2+ as its sole energy source. Rusticyanin is thought to be a principal component in the iron respiratory electron transport chain of T. ferrooxidans.
Statistics
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PSSM-Id: 259893
Aligned: 10 rows
Threshold Bit Score: 139.893
Created: 22-Feb-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Type 1 (T1) Cu
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1: Type 1 (T1) Cu binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:H C H MClick to see conserved feature residue pattern help
Evidence:
  • Structure:1RCY; Acidithiobacillus ferrooxidans rusticyanin Acidithiobacillus ferrooxidans binds copper through a Type 1 (T1) copper site.
  • Comment:Blue copper proteins are characterized by their conserved H...C...H...M copper ligands
  • Citation:PMID 8947572
  • Comment:Some members bind copper at the T1 site with three amino acid residues (HCH), instead of four (HCHM).

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                  #          
1RCY_A             26 TVTYSGKTVHVVAAAvlpg-------------fpfPSFEVHDKkNPTLEIPAGa-TVDVTFINTNkgFGHSFDITKKGPP 91  Acidithiob...
1A3Z_A             30 TVTYSGKTVHVVAAAvlpg-------------fpfPSFEVHDKkNPTLEIPAGa-TVDVTFINTNkgFGHSFDITKKGPP 95  Acidithiob...
1A8Z_A             28 TVTYSGKTVHVVAAAvlpg-------------fpfPSFEVHDKkNPTLDIPAGa-TVDVTFINTNkgFGHSFDITQKTPP 93  Acidithiob...
2CAK_A             29 TVTYSGKTVHVVAAAvlpg-------------fpfPSFEVHGKkNPTLDIPGGa-TVDVTFINTNkgFGHSFDITQKVPP 94  Acidithiob...
REF_jgi:Cmaq_1483 106 TIVFTSSDITLVALAmmgddavnmtgmplpgyahgDVFVIYGLiNPTLVIPQGa-VVHVIVINLDddMYHNLIVTAVPPP 184 Caldivirga...
NP_111971          61 SAIYINNSTTLPVLMgpmy------------apsmYSFEILRLiNPTIVVKEGv-SVHFIVINVDtdSYHNFAISNRGPP 127 Thermoplas...
NP_394955          65 STIYVNNSTTLLVMAgpmd------------gpsmYSFEIEGLfNPTIVIREGv-TVHFVVVNIDtdSEHNFVLSTRGPP 131 Thermoplas...
EEZ92491          107 SIAFESKNVSIVVLAmgvdravdltnstpsayitsDTFVIDGLiAPTLVLQKGs-TVHITFVNLDssEYHNVIITSTGPP 185 Candidatus...
YP_001541742      122 TIVFNSTTVYILVLAgps--------------snyLSFQVFNLtNPTIVVPKGa-TVKITVLDVSv-LPHSFGLVSKGPP 185 Caldivirga...
ACD03845           58 QVTYSGANPHTVIEQvlpg-------------fpfPSFEADKQtNPTLIYGAGvkKVTISVINTNggAEHSFMITKKGPP 124 Thiobacill...
Feature 1                                                                          #    #    #     
1RCY_A             92 YAVMpvid----------pivAGTGFSPVPKdg--------kFGYTDFTWHPt-AGTYYYVCQIPGHAATGMFGKIV 149 Acidithiobaci...
1A3Z_A             96 YAVMpvid----------pivAGTGFSPVPKdg--------kFGYTDFTWHPt-AGTYYYVCQIPGHAATGMFGKIV 153 Acidithiobaci...
1A8Z_A             94 FAVMpvid----------pivAGTGFSPVPKdg--------kFGYTNFTWHPt-AGTYYYVCQIPGHAATGMFGKIV 151 Acidithiobaci...
2CAK_A             95 YAVMpvid----------pivAGTGFSPVPKdg--------kFGYTNFTWHPt-AGTYYYVCQIPGHAATGMFGKII 152 Acidithiobaci...
REF_jgi:Cmaq_1483 185 YPYNvmpyvgmyggymgpgmmTMMQWLPPANyna------gyAYGYEYTITLnaPGTYWYLCTYPGHAQDGMYGEVI 255 Caldivirga ma...
NP_111971         128 YPYMvgmmg--------lgfeYKAPYLPPVHsd--------lYAYSEFNYTFssIGDYWYLCTYPGHAENGMYGEII 188 Thermoplasma ...
NP_394955         132 YPYMsgmeymg---sggfgfmTYMGFLPPTNsg--------hFYYYDFSYAFsqSGTYWYLCTYPGHAENGMYGKIV 197 Thermoplasma ...
EEZ92491          186 YQYMpmsam--------gglvSMMPFVQHADyqq------gqAYEYSYNASLnsDGTFWYLCIYPGHAQMGMYGKII 248 Candidatus Pa...
YP_001541742      186 YSASitpdqy-----pppfpgSQMPQSILVNgltpassssisGYVIEFNATT--PGVYWYICFVPGHAASGMYGKFI 255 Caldivirga ma...
ACD03845          125 YSAMpnpss--------lhamAVVPELPAASgg--------qFNTDTVEWTPpgPGTYYYLCKTPGHASTGMHGKIV 185 Thiobacillus ...

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