Cupredoxin domain of PKHDL1, a homolog of the autosomal recessive polycystic kidney disease protein
One member of this family is Fibrocystin-L, a homolog of the autosomal recessive polycystic kidney disease protein PKHD1. Human fibrocystin-L is predicted to be a large receptor protein (466 kDa) with a signal peptide, a single transmembrane domain and a short cytoplasmic tail. Fibrocystin-L is widely expressed at a low level in most tissues but is up-regulated specifically in T lymphocytes following activation signals. It may play roles in immunity.
Jiyao W et al.(2023). "The conserved domain database in 2023.",