1IC0,1IBY


Conserved Protein Domain Family
Nitrosocyanin

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cd04215: Nitrosocyanin 
Click on image for an interactive view with Cn3D
Nitrosocyanin (NC) is a mononuclear red copper protein
Nitrosocyanin (NC) is isolated from the ammonia oxidizing bacterium Nitrosomonas europaea. Nitrosocyanin exhibits remote sequence homology to classic blue copper proteins; its spectroscopic and electrochemical properties are different. The structure of NC is a trimer of single domain cupredoxins. Nitroscocyanin may mediate electron transfer. It could have a novel role as a nitric oxide dehydrogenase or a nitric oxide reductase in the oxidation of ammonia.
Statistics
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PSSM-Id: 259877
Aligned: 4 rows
Threshold Bit Score: 133.954
Created: 4-Feb-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Cu binding sitetrimer
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1: Cu binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:E C H HClick to see conserved feature residue pattern help
Evidence:
  • Structure:1IC0; Nitrosomonas europaea red copper protein binds copper.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                #       
1IC0_F         4 FNVVINAY--------------DTTIPELNVEg--VTVKNIRAFNvlnEPETLVVKKGDAVKVVVENkspISEGFSIDaf 67  Nitrosomonas eu...
1IBY_A         4 FNVVINAY--------------DTTIPELNVEg--VTVKNIRAFNvlnEPETLVVKKGDAVKVVVENkspISEGFSIDaf 67  Nitrosomonas eu...
YP_003527560  29 FKVVVNAY--------------DTTIPELNVEg--VTVKNIRAFNvlnEPETLTVKKGTSVKITVENkspISEGFSIDaf 92  Nitrosococcus h...
EKD90174      17 LVVIGGAWylsgkggvqaptptQTPGITLDQPdktFEVEGKPFEF---NPKELKVKKGDVVKITFKNt-qGFHDLSVD-- 90  uncultured bact...
Feature 1                                      #  #    #        
1IC0_F        68 GVQEVIK---AGETKTISFTADKAGAFTIWCQLHPKNIH-LPGTLNV 110 Nitrosomonas europaea
1IBY_A        68 GVQEVIK---AGETKTISFTADKAGAFTIWCQLHPKNIH-LPGTLNV 110 Nitrosomonas europaea
YP_003527560  93 GVQEVIK---AGETKTISFVADKAGAFTIWCQLHPKNIH-LPGSLNV 135 Nitrosococcus halophilus Nc4
EKD90174      91 GYNVKTKqiqAGESDTIQFRADKAGTFPMFCGVGTHRQQgMEGVLIV 137 uncultured bacterium

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