1WDA,2DEW


Conserved Protein Domain Family
PAD_N
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cd04214: PAD_N 
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N-terminal non-catalytic domain of protein-arginine deiminase
The N-terminal non-catalytic domain of protein-arginine deiminase has a cupredoxin-like fold, but lacks the Cu binding site. PAD (protein-arginine deiminase) and protein L-arginine iminohydrolase catalyze the conversion of protein arginine residues to citrulline residues post-translationally in a process called citrullination. The modification plays crucial regulatory roles in development and cell differentiation.
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Statistics
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PSSM-Id: 259876
Aligned: 17 rows
Threshold Bit Score: 120.56
Created: 4-Feb-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1WDA_A         14 IRVTpeq----------ptHAVCVlg----tlTQLDIcssap---edctSFSINASPGVVVDIahsppakkkstgsstwp 76   human
2DEW_X         15 IRVTpeq----------ptHAVCVlg----tlTQLDIcssap---edctSFSINASPGVVVDIahsppakkkstgsstwp 77   human
XP_002924053    3 LTIP---------------EAIMEarppsvelTVWCLmqtmhsapagytSFSINASPGVVVDVahsppakknstgsskws 67   giant panda
XP_003891259    9 RILC---------------FPICL--------IHSSAped-------ctSFSVNASPGVGVVIahsppakkkstgsstwp 58   olive baboon
NP_990374       7 VQLCtqr----------ptSTVCVlg----teLSLDIqgsap---kdaiAFHVQGTPGVKVYVvhetqsvklpssvtrwp 69   chicken
XP_001506089  493 VCTQgylefqklyqwqpkrNSICA--------PGSST------------AFNISSTTGVVIDTansfpvkktptgltkws 552  platypus
NP_037490      11 LKMPt--------------HAVCVvg----veAHVDIhsdvp---kganSFRVSGSSGVEVFMvynrtrvkepigkarwp 69   human
BAA85974        9 VSLEhp------------tSAVCVag----veTLVDIygsvp---egteMFEVYGTPGVDIYIspnmergreradtrrwr 69   human
NP_001153973    6 FRLDtgk----------tlRALYVv------gTVLKVnlnrsa-ppsstYFSVKCSPNVQYRItpppaksg--piptpfn 66   rainbow trout
XP_003765105   60 LELPsssin------lenrYTIFQt------eTLVHLfynsv--ppravTFKVTGSSSVQIYMeydpknvseppaderwp 125  Tasmanian devil

1WDA_A         77 lDPGVEVTLTmkaaSGSTGDQKVQISYYGPKt-----PPVKALLYLTA 119  human
2DEW_X         78 lDPGVEVTLTmkaaSGSTGDQKVQISYYGPKt-----PPVKALLYLTA 120  human
XP_002924053   68 lDPSLEVSLRmkaaSSSTGDQKVQISYYGPKt-----NPVQALLYVTG 110  giant panda
XP_003891259   59 lDPGVEVTLTmkaaSGSTGDQKVRPAHLGPGwvpqprTLTNPLLLLGG 106  olive baboon
NP_990374      70 lATGTEVLLTmeaiSKDVGDEKVRISYFGEAsg---vPVGRAMLYLTC 114  chicken
XP_001506089  553 lNPKVEVMVMlsapSSTINEEKVRISYYGPKag---pVVGKAVLYLTG 597  platypus
NP_037490      70 lDTDADMVVSvgtaSKELKDFKVRVSYFGEQed---qALGRSVLYLTG 114  human
BAA85974       70 fDATLEIIVVmnspSNDLNDSHVQISYHSSHep---lPLAYAVLYLTC 114  human
NP_001153973   67 gNTVLLLTMDt--aSEVENDSKLSVMYYGKKk----eVLGKAVVHLTA 108  rainbow trout
XP_003765105  126 lDADVDVVLSveaaSTNVDDVKVRVSYYGKNgs---qALGQALLHLTA 170  Tasmanian devil
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