2YEV


Conserved Protein Domain Family
CuRO_CcO_Caa3_II
?
cd04213: CuRO_CcO_Caa3_II 
Click on image for an interactive view with Cn3D
The cupredoxin domain of Caa3 type Cytochrome c oxidase subunit II
Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of most bacteria, is a multi-chain transmembrane protein located in the inner membrane the cell membrane of prokaryotes. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. Caa3 type of CcO Subunit II contains a copper-copper binuclear site called CuA, which is believed to be involved in electron transfer from cytochrome c to the cytochromes a, a3 and CuB active site in subunit I.
Links
?
Statistics
?
PSSM-Id: 259875
Aligned: 32 rows
Threshold Bit Score: 160.863
Created: 13-May-2005
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
CuA binuclearoligomer
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1: CuA binuclear center [ion binding site], 5 residue positions
Conserved feature residue pattern:H C C H MClick to see conserved feature residue pattern help
Evidence:
  • Structure:2YEV; Thermus thermophilus Caa3-Type Cytochrome Oxidase binds 2 Coppers at the CuA center.
  • Comment:Electron transfer is believed to proceed from CuA via heme a to the binuclear center
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                            #                           
2YEV_E       116 AMKVEVTGYQFWWDFHYPEl------gLRNSNELVLPAGVPVELEITSKDVIHSFWVPGLAGKRDAIPGQTTRISFEPKE 189 Thermus thermop...
NP_980286    129 TIVVDVTANLYWWEFSYKSe------kIVTSQDLVIPTGKKVYLNLKGADIKHSFWVPSLAGKMDTNTDNVNKMWLKADK 202 Bacillus cereus...
NP_692358    126 HVNIEVTGNQYWWHFNYAGe------eVVTSQDLYIPTGERVYLNMLSSDVTHSFWIPSISGKMDVNPENVNTMYIEAHE 199 Oceanobacillus ...
YP_001814457 127 NEVINVTANLYWWEFEYPDk------gVSTGQELVIPVGKRVAVNLTSKDVIHSFWVPALSGKTDTNPGLDNEMWLQAQE 200 Exiguobacterium...
YP_001187756 127 PLRIEVVGHQWWWEVRYPEs------gVVTANQLHLPTGRPVDLDVSSADVIHSFWVPRLGGKIDMIPGRDNRIRLQADQ 200 Pseudomonas men...
NP_296338    166 TLGIEATGAQFWWNFTYPGspvqggstVANGNEMVMPAEQKVAISTTSKDVIHGFWAPNLGGQRASIPTVKRVWELDTQR 245 Deinococcus rad...
YP_603879    157 AEKIDVLGKQFWWNFSYPGapaaaggnVTNGNELVLPTGKWASLTITSGDVIHAFWAPNLGGQRDATPGTQKTWQIQTDR 236 Deinococcus geo...
YP_157110    125 PLRIDVTGRQWQWDVAYPGg------gAVLVDELHLPAGRPVHLHVTSADVIHSFWVPRLGPKIDAVPGRTNVLRLQADE 198 Azoarcus sp. EbN1
YP_782772    441 TLRIDVEARQWQWTFRYPEdre---gvGLSINTLHIPVGRPIDLRVSSADVIHSFWVPRLGGKIDAIPGHVNRIRLSASQ 517 Rhodopseudomona...
YP_318919    125 PLKVAAQARQWTWSFAYPDsr----raTLSVNVLHIPAGEPVDVIVTTKDVIHSFWVPRLGGKIDAIPGHRNVVRLQADR 200 Nitrobacter win...

Feature 1               #   #   #  #       
2YEV_E       190 PGLYYGFCAELCGASHARMLFRVVVL 215 Thermus thermophilus HB8
NP_980286    203 SGTYNGFCTEFCGPSHSLMQFKVKAL 228 Bacillus cereus ATCC 10987
NP_692358    200 EGVYWGKCAELCGPSHSLMDFKVIAV 225 Oceanobacillus iheyensis HTE831
YP_001814457 201 AGTYYGKCAELCGPSHALMDFKVIAL 226 Exiguobacterium sibiricum 255-15
YP_001187756 201 PGVFRGQCSEFCGTQHSHMILDVHAH 226 Pseudomonas mendocina ymp
NP_296338    246 PGVYQGNCSQLCGASHANMRFKVIAL 271 Deinococcus radiodurans R1
YP_603879    237 AGVYQGNCNVLCGASHANMRFKVIAL 262 Deinococcus geothermalis DSM 11300
YP_157110    199 AGSLRGQCSEFCGTGHAHMVLKVQVH 224 Azoarcus sp. EbN1
YP_782772    518 AGIYRGVCAEFCGTEHTRMEFSVEAH 543 Rhodopseudomonas palustris BisA53
YP_318919    201 PGVYGGVCAEFCGAGHSAMRFTVLAH 226 Nitrobacter winogradskyi Nb-255

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap