Conserved Protein Domain Family
GT_2_like_d

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cd04196: GT_2_like_d 
Subfamily of Glycosyltransferase Family GT2 of unknown function.
GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
Statistics
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PSSM-Id: 133039
View PSSM: cd04196
Aligned: 61 rows
Threshold Bit Score: 217.498
Threshold Setting Gi: 118587021
Created: 29-Jun-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Probable
Feature 1:Probable Catalytic site
Evidence:
  • Comment:Residues conserved among GT families of 2, 7, 13 and 43

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                            #                                           
ZP_01116129   13 DVLILTYNGgsYLHPQLTSIAEQLep--gdRIIVSDDGSTDDTLRIlqefqqtylkenvellvyqGPGKGVIQNFFSG-- 88  Reinekea sp. ME...
CAI34585       4 SVAMTTYNGadYLLEQLESLRTQSlm--adEVIIVDDCSTDNTVELldmyiqkyh-ldnwvlirnSSNIGWRKNFRKA-- 78  Streptococcus p...
YP_001114366   5 TVLLSTYNGqaYLRELLDSVFAQKnv--iaSIVIRDDGSSDNTVDIieeyisng----yditllkESNVGATRSFHLLtq 78  Desulfotomaculu...
ZP_02075261    5 NVLVSTYNGekYIEEQLKSIDCQTys--nvHVYVRDDGSTDHTVELvnryirene-lsdkytvatGENIGFSKSFHLLm- 80  Clostridium sp....
CAD47144       5 AVLMATYNGekFISEQLDSIRQQTlk--pdYVLLRDDCSTDETVNVvnnyiakhe-legwkivknDKNLGWRLNFRQLli 81  Streptococcus a...
AAN63686       4 SVIIATYNGskFIEEQFDSILAQSvq--pdEVVITDDGSKDNTREVvqryidehdlnkkwhlhvnEKNKGYARNFLDG-- 79  Streptococcus t...
ZP_01773265   10 CIVLPTYNGgkYLAKQLDSILEQTwp--ncSVYIRDDGSTDETVEIaqwycrsns--sihliqdsIGNLGCPNSFYEIi- 84  Collinsella aer...
ZP_01544452    6 TVIMATFNGskYIHDQLQSIFNQSil--ptRVIIRDDKSSDDTAEIvnqfidgnnlraswdfkvnQKRKGWRENFISM-- 81  Oenococcus oeni...
CAI33942       6 AILMATYNGe-KYIKEQIESILNQdtdfdfTLIIRDDGSTDNTKNIireyvds-----gkiifieGQNKGAARGFISLl- 78  Streptococcus p...
NP_815829      8 TVVMATYNGekNILEQLDSLKNQSkk--idEVLIWDDCSTDSTVKIienfisenklgetwhlqinTENLGWRKNFFNL-- 83  Enterococcus fa...
Feature 1                        ##                                                              
ZP_01116129   89 ---IQHTKAEYTFIADQDDVWLPGKRQLFAkq--mqCSSKPHLIFSDAWLWNSLDtntdtsfwqqqkinps---harqls 160 Reinekea sp. ME...
CAI34585      79 ---LQETTGDIVFLCDQDDIWNKDKISLMVke--fhKSPSIELLASNYEILDFGRndkikirdveldngav---vpfslk 150 Streptococcus p...
YP_001114366  79 yvyGQKEKTPFYAYCDQDDIWNPDKLNVAVdklralSEDLPNMYFSNLILYDGKTirnelafdvpcnf--------epqk 150 Desulfotomaculu...
ZP_02075261   81 ---QMADSGEYWAFCDQDDVWYPNKLSNAVkwmqtqKNDIPLLYQSKIAIGNSDLseivpykyenyny---------nfq 148 Clostridium sp....
CAD47144      82 --dVLAYEVDYVFFSDQDDIWYLDKNERQFai--msDKPQIEVLSADVDIKTMSTeasvphfltfsssdr----isqypk 153 Streptococcus a...
AAN63686      80 ---AMLTTGDIVFFCDQDDIWISDRVKKMSev--meKNPKINLLCSNLEPFYYEEdtrkwsekdlkamktdgsleicdlt 154 Streptococcus t...
ZP_01773265   85 ---KRVPEYDYYAFADQDDIWKTDKIERAVraiensGDKVPTVYFSSFSYVNEDGetiresapqdkyl---------sfh 152 Collinsella aer...
ZP_01544452   82 ---LRQTETDVVFYSDQDDIWQENKVEATLta--feAEEEMEVLVSDYVIIPKEQnllvvrqleetpvssq--lykvdlt 154 Oenococcus oeni...
CAI33942      79 ---CDNPGYDYYAFSDQDDVWNHNKLQKGIws--lsKYTGPALYCSNCELVDSELnsigrnthrkrpny-------tles 146 Streptococcus p...
NP_815829     84 ---LNAATKEIVFTCDQDDIWDASKIEVMCea--faNTDVKVLVSDYTELVEPGGlaeelkkidsvklpnqk-aeqiifn 157 Enterococcus fa...
Feature 1                                                                                      
ZP_01116129  161 tlifrntvqGASMAINRALIERISLHPdi---------vMHDWWCALHANa-fGSISIIFEPtllYRQHDANQIGALR 228 Reinekea sp. MED297
CAI34585     151 nksisvmrpGCTFAVKRELIVLLEKYDid--------rfGHDNILWNLAMi-rGTLYLYLKRlihFRRHETSASAPNQ 219 Streptococcus pne...
YP_001114366 151 kafarvftyGCTCVFNQEALKTISLAGgen-------kiYHDNWLFEVCAf-lGNTVFDQSSyilYRQHSNNVSGEIK 220 Desulfotomaculum ...
ZP_02075261  149 kaftsniffGFAMVINRELYDRLIRADfdq-------ikYHDWFAAIIVSa-fGKYVFSEEIeavHRQHENNASPLYF 218 Clostridium sp. L...
CAD47144     154 vydyqtfrpGWTIAMKRDFAQAIADNWtfg------aniSHDNLIETTASi-iGNGYNLNESvgvHIRYGGNASGNSK 224 Streptococcus aga...
AAN63686     155 peyfhlkrsGCTMCIRKTFLEEIMPYWta--------nwPHDDFVWKMAVi-sSSCAILHFVsmrRRMHSNNATVIRV 223 Streptococcus the...
ZP_01773265  153 ntlfytpglGFTIVFNRLACRAFILEVdpg-------neMHDRWLIRCASa-fGKVLFDSVCtasHVRHSSAVTSGDN 222 Collinsella aerof...
ZP_01544452  155 ltnlavyrpGCGMALRKSIIDSTIEIFrrvkvdfnavaqTHDQAAWLAAVa-rGTLYHLHQPlfiRRIHPDSTWQTEK 231 Oenococcus oeni A...
CAI33942     147 ilclascaqGCTSVFNKELASIIQENDvpd------tfiMHDSLITCLCAligGKIIYDEIPsmkYRMHDDNIFGMVS 218 Streptococcus pne...
NP_815829    158 ennlflrrpGCVYAIRKSFIANVNLYAsem------enpVHDMAMWGSSLl-sDGLYIVREElirWRKHGQSSFKKEI 228 Enterococcus faec...

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