Conserved Protein Domain Family
Glucan_BSP_MdoH

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cd04191: Glucan_BSP_MdoH 
Glucan_BSP_MdoH catalyzes the elongation of beta-1,2 polyglucose chains of glucan.
Periplasmic Glucan Biosynthesis protein MdoH is a glucosyltransferase that catalyzes the elongation of beta-1,2 polyglucose chains of glucan, requiring a beta-glucoside as a primer and UDP-glucose as a substrate. Glucans are composed of 5 to 10 units of glucose forming a highly branched structure, where beta-1,2-linked glucose constitutes a linear backbone to which branches are attached by beta-1,6 linkages. In Escherichia coli, glucans are located in the periplasmic space, functioning as regulator of osmolarity. It is synthesized at a maximum when cells are grown in a medium with low osmolarity. It has been shown to span the cytoplasmic membrane.
Statistics
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PSSM-Id: 133034
View PSSM: cd04191
Aligned: 17 rows
Threshold Bit Score: 381.626
Threshold Setting Gi: 126734550
Created: 17-Jul-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Ligand bindingDXD motif
Feature 1:Ligand binding site
Evidence:
  • Comment:Predicted ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1             # #                                                                        
YP_547965    160 TAIIMPICNEDVRTVFAGLRATCESVAmtgh-vknfDVFVLSDSSHPAIIRaeraawedlrsqlashpeqpqievYYRLR 238 Polaromonas sp....
YP_001209535 119 CAIVMPVYGEDPAMTGAALLAIADDLKnsai-aarcELFILSDTQNVDAWLketaafsll-------rarcalplWYRRR 190 Dichelobacter n...
A3D3U0       134 TAILMPTYNESPDRVFSAVSVMAETLSqtgh-ghafDWFILSDTTDPDIALleeqaflvlr-----qethkhsrvYYRRR 207 Shewanella balt...
YP_749994    129 TAVLLPIYNEDPLRIRATIEAMSADLIatap--gkyAFFILSDTNRADAWIaeeqtfldli-----nnsqpqcpvYYRRR 201 Shewanella frig...
Q9A6R5       145 TAILMPVYNEDAAAVFARLRAMDASIAetgs-arnfDIFVISDTRDAQVALaeqacfarf-------rreancnvYYRIR 216 Caulobacter vib...
ZP_01227727  166 TAIVMTLRNEAPEPSFERLEAMRRSLAktgl-adhfRFFILSDTDDAEIGQreeaafegft-----aifapghepVYRRR 239 Aurantimonas sp...
CAD74760      89 TAVLVPVYNESPIDVFARVEAMVRSLGpdq----rfDFFVLSDTNDSEVWLaeelawsqlmdr-leeqvstscnvYYRHR 163 Rhodopirellula ...
ZP_00633200  148 IAVVMPVYHEDAAATTGLLAALARDLYrvgl-adraEIFVLSDSREPRAVFeemaaisrl-------rdispvpvWYRRR 219 Paracoccus deni...
ZP_00047747   95 TAAVVAIHAEDPIAVFSAIRVMARSLQreggdgsdiDIFVLSDTREGAISAveeheftriqaw-arregrgmpriRYRRR 173 Magnetospirillu...
ZP_01750296   85 TAVLVALCGEDAGPLAAYLNHFTRGLGavgl-gsetTVFVLSDTSAAPQIAaeeaalad---------liaqgriVYRRR 154 Roseobacter sp....
Feature 1                                      #                                                 
YP_547965    239 KRRTDRKAGNVADFCRRWGKdyRYMVVLDADSvmsgdclvamvklMEANPKAGIIQTATQAIGHVTLHARAQQFASRVTG 318 Polaromonas sp....
YP_001209535 191 SKNIGRKAGNIEQFIKTWGGryAYFLLLDADSlmsaetivkmvarMDADPNLALLQTQPRLLGAESLLARTIQFAGGLYG 270 Dichelobacter n...
A3D3U0       208 RKNVARKAGNVADFCRRWGSryDHLLVLDADSlmesstitglaqrMQADPDAGLIQTIPSLINGTTLMARLQQFAARIYG 287 Shewanella balt...
YP_749994    202 HQNSERKAGNIGDWVQRWGGdyEAMIVLDADSimsaksmvtlsrrLAGAPGVGLIQTLPTLVFANTLYSRLQQFANQCFG 281 Shewanella frig...
Q9A6R5       217 KENTGRKAGNVADWVSRWGSayEHMLVLDADSlmtgeamvrladaMERHPGAGLIQTMPMIINGQTIFARTLQFATRLYG 296 Caulobacter vib...
ZP_01227727  240 RDNAGYKAGNIAAFLADEGAayDYFLPLDSDSvmagdvivrmvaaMERHPRLGILQSLVVGMPANSGFARIFQFGMRHGM 319 Aurantimonas sp...
CAD74760     164 RENVARKAGNIADFCRRWSDpyPFMIVLDADSllepdtmiemvrrMRADDRLGILQVPPTPIGRQSWFARMQQFAAAAYG 243 Rhodopirellula ...
ZP_00633200  220 SSNKGRKAGNVGEFVRRWGGryDQMVVLDADSvvgaatirtlsarMNADPAIGLIQTMPMLVGGQTIFARLTQFAGRIYG 299 Paracoccus deni...
ZP_00047747  174 TENTGRKAGNIAEFCETYGPeyDFMIVLDADSlmtgaamrrlarlMEENPRLGLIQTVSYAAGRDTLFARIQQFAVRLYA 253 Magnetospirillu...
ZP_01750296  155 VENTNKKPGNIADWLDSHGSdfDYMVVKDADSrmtpdsikqliwqLESRPDTGLLQAAIALIPGRTRFGRHQRISSRLLG 234 Roseobacter sp....
Feature 1                                                                                        
YP_547965    319 RLFTLGMQFWQMGESHYWGHNAIIRIAPFMQHCALAhIKGTGGMAGSIMSHDFVEAALMRRAGfhvwlvadlVGSYEQQP 398 Polaromonas sp....
YP_001209535 271 KIVGRGISAWQGYEGNYWGHNALIRTQAFAESCGLPvLKGRRPIGGHIMSHDFVEAALLCRRGwqvrmdsdlNGSYEGLP 350 Dichelobacter n...
A3D3U0       288 PVIGTGLGWWVQKEGNFWGHNAIIRTEAFMTAAGLPnLKGKPPFGGHIMSHDFVEAALIRRAGwsvviaydlPGSYEECP 367 Shewanella balt...
YP_749994    282 PIYAEGLSAWHGLSSNFWGHNAIIRTKAFAESCHLPiLSGKAPFGGHVLSHDFIEAALLRRAGwgvrfdtdiEASFEEAP 361 Shewanella frig...
Q9A6R5       297 RVAWTGLAWWSGSESSFWGHNAIVRTRAFAETCGLPhLPGPKPFGGEVMSHDALESALLRRGGwsvhlapylDGSYEESP 376 Caulobacter vib...
ZP_01227727  320 RSFTMGAAWWNADCGPYWGHNAVIRTAAFRAHCKLPnLPGRPPLGGPVLSHDQLEAAYMRRAGyevrvipveTRSYETNP 399 Aurantimonas sp...
CAD74760     244 PVFCEGFDAWAAEQGNYWGHNAIIRVEAFCDCCDLPvLPGQAPLGGEILSHDFVEASLLVRRGwkvrlandlGGSYEECP 323 Rhodopirellula ...
ZP_00633200  300 PAVARGVAAWSGDSGNFWGHNAIIRVEAFAQCCGLPeLPGKPPFGGTILSHDFVEAALLRRAGwkvrldhdlRQSFEGCP 379 Paracoccus deni...
ZP_00047747  254 PLSLRCLETWQGPDGSYWGHNAILRVEAFANNAELPvLSGKPPLGGEILCHDIGEGALLRRAGwevrllpemGGTWEEMP 333 Magnetospirillu...
ZP_01750296  235 PAFGRGFAAWSGKAGNYWGHNAIMRVAAFRSAAALPrLSGQAPFGGDLLSHDFVEAAWMRRAGwdielapdmRGSAEDAP 314 Roseobacter sp....
Feature 1                            
YP_547965    399 PDLlaelqRDRRWCQGNLQN 418 Polaromonas sp. JS666
YP_001209535 351 PTLeelsrRERRWAQGNLQH 370 Dichelobacter nodosus VCS1703A
A3D3U0       368 PSIidlavRDRRWCQGNLQH 387 Shewanella baltica OS155
YP_749994    362 PSLidvmiRDRRWCQGNLQH 381 Shewanella frigidimarina NCIMB 400
Q9A6R5       377 SNLldfatRDRRWCRGNIQH 396 Caulobacter vibrioides
ZP_01227727  400 PTLpdfakRDLRWCQGNMQY 419 Aurantimonas sp. S185-9A1
CAD74760     324 TTLtdyaqRDQRWCQGNLQH 343 Rhodopirellula baltica SH 1
ZP_00633200  380 PTLldmavRERRWAQGNLQH 399 Paracoccus denitrificans PD1222
ZP_00047747  334 TNLidllgRERRWCQGNLQH 353 Magnetospirillum magnetotacticum MS-1
ZP_01750296  315 QTLhaffrRDRRWCQGNLQH 334 Roseobacter sp. CCS2

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