Conserved Protein Domain Family
GT_2_like_c

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cd04186: GT_2_like_c 
Subfamily of Glycosyltransferase Family GT2 of unknown function.
GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
Statistics
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PSSM-Id: 133029
View PSSM: cd04186
Aligned: 51 rows
Threshold Bit Score: 127.29
Threshold Setting Gi: 54040191
Created: 5-Jul-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:Probable Catalytic site
Evidence:
  • Comment:Residues conserved among GT families of 2, 7, 13 and 43

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                 #                                      
CAJ72309      43 IIIPVFnkveYTKKCLEALFkntp-------gdiyEIIVVDNASSDETpeflkrmin--------klevitnqeNMGFTS 107  Candidatus Kue...
NP_903550    557 VIIPSKdkleCLTPCLQSLFritg-------yqnfEVLIVDNGSEDPEtfefyqemkaqh---pdririlsydaPFNFSA 626  Chromobacteriu...
YP_629297      8 ISIVNHsnpeLLHDCLRTLYattr-------dssfEVWIVDNATGGRGvdamrrdfp--------qvrwlfnteRKGFSA 72   Myxococcus xan...
CAH07268       7 TIVTYKnpdsVLLKAINSFLntk---------levRLYIIDNSPTDYLkdisydpr----------veyifmnsNNGFGA 67   Bacteroides fr...
ABA50225      54 SIVVYRpdvrQLTRTLSSLLvalekldgsrpgartALYLVDNGGAPGSlpafdemlarg-----idctvinghgNVGYGR 128  Burkholderia p...
ZP_00943271    7 SIVLYNnpidQIRHCIESLQvda----------rvHVLLVDNSENKGSyaglaaen----------veildapgNVGFGR 66   Ralstonia sola...
AAC35917       8 TISIVTynsrYIFNVLDQLKaelgt------dsiyDIHIYDNHSETAYleklttyep--------fitihraeeNQGFGH 73   Enterococcus f...
CAI78731      15 SIVLHNsclmLLRRTLHSLFiaireaqqtdclryvTVTLVDNASGRYYreeletlvanwpesagcqlmcslqpgNRGFGH 94   uncultured gam...
P64868        10 ITVPVFgqheYTHALVADLEre-----------gaDYLIVDNRGDYPRigterv---------------stpgeNLGWAG 63   Mycobacterium ...
AAD05464       6 SVVVYReteeTLDDLLDSLAaqasc-----pdtvvRVWLRNNDPADADrwdrfvhdrswy---pfeisishspqNVGFGR 77   Burkholderia p...
Feature 1                             ##                                                         
CAJ72309     108 ACNQGAkia---kgnYLVFLNNDTEPQPGWLesmvkl-aesdsKIGIVGSKlvypdgrlqeaggiifcdgsgs------- 176  Candidatus Kue...
NP_903550    627 QCNLGArea---rgeYLLLLNNDTEVIFPQWlermla-taqqpGVGAVGARllypevglvqhagivlgmpggmysva--- 699  Chromobacteriu...
YP_629297     73 NHNQVLrqa---rgrHFCIFNDDTIVHEGAFdalvrf-mddnpRVGMAGARllnadgtiqnctfrpmslagqlfdivf-- 146  Myxococcus xan...
CAH07268      68 GHNVILrdpe-kmgkYHLILNPDISFEEGTLeklydy-megklDVGNVMPKviypngelqylckllptpkdwivrmflp- 144  Bacteroides fr...
ABA50225     129 GHNHAIerv---asrYHLILNPDVDLDENALvtaidf-fdahsDVGLVAPRvddeqghtqylcrryptlfdlfvrgfmpa 204  Burkholderia p...
ZP_00943271   67 GHNLVLgrlaalrseVHLVVNPDIVVKPGCVqsvtdv-lrqrkDVALVGPRvvspdgdlyrsckllptpwnlfarrfa-- 143  Ralstonia sola...
AAC35917      74 GHNQVLfna---stkYAIIFNPDVLVTKDVLdrlldr-ikidkNIAVVSPKvlnedgttqylvrqkldvfdymlrfipfq 149  Enterococcus f...
CAI78731      95 GHNTVIegl---ksdYHLVLNPDVELEKDTLcvglsa-leankDIVLVSPRvngeagdqeflckryptvlvlllrgfapg 170  uncultured gam...
P64868        64 GSELGFrlafaegysHAMTLNNDTRVSKGFVaalld--srlpaDAGMVGPMfdvgfpfavadekpd-------------- 127  Mycobacterium ...
AAD05464      78 AHNATFema---dapFFFVLNPDTRLHSTAVsalrkaidtsagDVGAWELRqlpyehpkly------------------- 135  Burkholderia p...
Feature 1                                                                                        
CAJ72309     177 ---------nfgrggnpyeegfndacevdyCSGACLLVRkelFENIGGMDHRYSp--aYYEETDLCFAAreKGYTVMYAP 245  Candidatus Kue...
NP_903550    700 ----dhifegmdylypgymnrsltmqnysaVTAACLLVEkqiYDLVGGFDEESLq--vCFNDVDFCLKVqaAGLRNVYNP 773  Chromobacteriu...
YP_629297    147 ---lprplhflkamaidpaqyghdearvswVLGACIVVReeaLAEVGLLDEQMSpl-gNTEDTDWCVRAwkAGWEVAFCP 222  Myxococcus xan...
CAH07268     145 ---iksiknridynfemkfadydremnipyLSGCFMFLRksvIEGIGVFDEGIFm---YGEDTDLNRRIy-RKYKTMYYP 217  Bacteroides fr...
ABA50225     205 girnafsrrlaryemrdvinatdvvwdpaiVSGCFMLFRtdvLKALGGFDARYFl---YFEDYDLSLRTh-DVARVAYVP 280  Burkholderia p...
ZP_00943271  144 ---prpfyaaadaryelqafdydrelrlhnLSGAFLAFRseaFAALGGFDPRYFm---YLEDVDICRRAa-SLGAVIFVP 216  Ralstonia sola...
AAC35917     150 --fvkkifdkrlsiyecrdlsdtettdikmGSGCFMLIDrekFVEIGGFDERFFm---YFEDNDLCLRFgkAGYRILYTP 224  Enterococcus f...
CAI78731     171 -fflrlfhnrlsayemrdqcrsdqpvdvaiASGCFMLVRspvLRDVGGFDETFFl---YFEDFDLSLRLe-GCGRLVFEP 245  uncultured gam...
P64868       128 ---------------aesyvpraryrkvpaVEGTALVMSrdcWDAVGGMDLSTFgrygWGLDLDLALRArkSGYGLYTTE 192  Mycobacterium ...
AAD05464     136 ---------------------dpvslstdwVTGAAVVFRraaFAQVRGFEPRIFm---YGEDVDLSWRMraAGWVLHYVP 191  Burkholderia p...
Feature 1                
CAJ72309     246 nsvvIHHE 253  Candidatus Kuenenia stuttgartiensis
NP_903550    774 fvvlYHSH 781  Chromobacterium violaceum ATCC 12472
YP_629297    223 eaviTHLT 230  Myxococcus xanthus DK 1622
CAH07268     218 qvtiTHHF 225  Bacteroides fragilis NCTC 9343
ABA50225     281 rvliRHYG 288  Burkholderia pseudomallei 1710b
ZP_00943271  217 qaevVHEH 224  Ralstonia solanacearum UW551
AAC35917     225 fetvVHMY 232  Enterococcus faecalis
CAI78731     246 smriLHHG 253  uncultured gamma proteobacterium
P64868       193 mayiNHFG 200  Mycobacterium tuberculosis H37Ra
AAD05464     192 havvVHPT 199  Burkholderia pseudomallei

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