Conserved Protein Domain Family
GT_2_like_b

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cd04185: GT_2_like_b 
Subfamily of Glycosyltransferase Family GT2 of unknown function.
GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
Statistics
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PSSM-Id: 133028
View PSSM: cd04185
Aligned: 28 rows
Threshold Bit Score: 203.251
Threshold Setting Gi: 765062
Created: 16-Jun-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Probable
Feature 1:Probable Catalytic site
Evidence:
  • Comment:Residues conserved among GT families of 2, 7, 13 and 43

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                       #                                             
NP_784881   5 AIVVTFNRKQLLIESITALLNQTvp-paKIIIIDNHSTDGTKAELQTadilanp---------------------svdyr 62  Lactobacillus plan...
NP_695276  13 LIVTTYKRQQLLETLFDSILALEqa-pwRIVIVDNEQSDQTADMVAAfagkvtgqwgttva-------dqsgneervvya 84  Bifidobacterium lo...
CAI33743    6 ALVVTYNRSKYLQKALEGILNQQqe-isGILIYNNNATDNTEEILMKfgyvdskgdkikeny----lystekdgkhfyyy 80  Streptococcus pneu...
AAC98409    5 ALIVTFNRLDKLKKTVAETLKLDf---sTVMIVNNGSTDGTPAWLDSitdsr------------------------vvvl 57  Klebsiella pneumoniae
AAN05124    8 AVVVTYNRLDKLKVTLARLLESPaeelaQVVVVNNASTDGTADWLETqhdpr------------------------ltvl 63  Ruegeria sp. PR1b
YP_922601   9 VVVVTYNRADLLAHMLDGLAAQTrp-adAIFVIDNASSDHTRALLTEqvaaarpg-------------------lplqvt 68  Nocardioides sp. J...
EAY57453   15 VVLVTYNRKDLLLECLDGLLRQTrp-idGLVLIDNASTDGTADALYAqkflpevpplnarsvwefrreslregemtfvyl 93  Leptospirillum sp....
ABF01012   10 LVIVTYNRCNLLMEMLSSIENMSvk-pdIVYVIDNNSSDNTSSVVTEcdsrkni---------------------nikyh 67  Escherichia coli
ABL63461    8 CIIVTYNRVSLLEKVLDGVLTQTfp-asKIIIIDNNSSDDTQIIIKQkksefk----------------------qieyy 64  Salmonella enterica
AAK68916    5 AVVVTYNRLALLKKVIDLLKRQTrq-ldSIVIVNNGSTDGTKEWLEQekni---------------------------tl 56  Bacteroides fragilis
Feature 1                                     ##                                              
NP_784881  63 yLTKNIGGAGGFARGMqiaaadpnlDWASMSDDDAIFEPDYFEKLIayqqdhpnrQILTGSVYIEDGrlqadqrnrftnw 142 Lactobacillus plan...
NP_695276  85 pQTENLGGAGGFSVGVakay-elgaAWFWVMDDDVAVLPDAIAKLSkwt---dkhEVIQGSRFDYDGgpfywqydfivpl 160 Bifidobacterium lo...
CAI33743   81 hNDENLGGAGGFANGIrlis-eldyDYVWIMDDDVYPEPNCLSEIMkqms-vqnvQVGIPNRTDENFddraiigfdfddy 158 Streptococcus pneu...
AAC98409   58 nLPVNSGGAGGFKAGSqhicdaidtDWVFFYDDDAFPASDILEKFFalek--kecQVFTGLVKDLHGhpcamnlpfrkvp 135 Klebsiella pneumoniae
AAN05124   64 tSETNSGGAGGFAWGMrhavetcapDWLVVMDDDGRPAPGALAAFHalpe--dkwDAIAAAVYFPSGeicemnrpsrnpf 141 Ruegeria sp. PR1b
YP_922601  69 hVEENLGGAGGFHLGVgmah-aaghDRIWLMDDDVVPAPDCLEILLah-----deACLMSVRQDTHGrlvekaalrfdlr 142 Nocardioides sp. J...
EAY57453   94 rLPVNEGGSGGFHEGVkkal-efdcDWLWMMDDDVEPDEGCLQGQLafs---eisKCIHPRKYFQDGlahewegyisavt 169 Leptospirillum sp....
ABF01012   68 nTGYNAGGAGGFYIGSkmay-edgwDRIWLADDDIVLDKECLSNAMeyd---dgrTILQPMRYNMDGscaeisaiqydls 143 Escherichia coli
ABL63461   65 nTGENLGGAGGFNYGFriae-khyyDFIWIMDDDLLPEKTCLEHLIlsa---dhdGIYQPLRFNLDGscaelspvvydls 140 Salmonella enterica
AAK68916   57 iNQSNSGGAGGFETGVkyay-eneaDWIWMMDDDVFPNIDCLEKLLgwt---sisQCIQPRRYYSDDvevnfeqwldpit 132 Bacteroides fragilis
Feature 1                                                                                     
NP_784881 143 stfqa-------------qavpereyrgnfefdqyTFCGVFMSvavIKQVGVADAg-yFIWWDDCEYAVRTAKLSRpv-n 207 Lactobacillus plan...
NP_695276 161 gipnp-------------iapaafgpagyrvmdtlCFEGGLFNrrvVTEIGLPDPr-fFIYWDDTMYGYRASKVTNpi-v 225 Bifidobacterium lo...
CAI33743  159 hkfwtem---------rktvtygpfdeeaikvvdmPFEGPVVEmalLRKVGIPDSg-fFIEYDDSDFAQRLQQYSDii-f 227 Streptococcus pneu...
AAC98409  136 ssfadtlr------yirtpqrfvptidesvmvetvSFVGMIISskvLQEHIDHIHdelFIYFDDLYFGYALTLDGQkily 209 Klebsiella pneumoniae
AAN05124  142 wrlsefirtalgggrsgfhldpaeyqgqgtsidvtSFVGFFISaraIARIGYPDPs-lFIYGDDGIYTLGLTAAGGrigf 220 Ruegeria sp. PR1b
YP_922601 143 nplsvrpkt----amveteygsrdlmpdrvelenvAFEGFMLRrevVDAIGLPDPs-yFIFYDDVDYAVRARRAGFhiwa 217 Nocardioides sp. J...
EAY57453  170 grrvf------------qpdisfrkgfsfctintgCFEGMLIHrsvVEKIGLPDKr-fFLGGDDSVYGFLAHYHTPvl-y 235 Leptospirillum sp....
ABF01012  144 npfylrpk-------rktvqnifnknilsydiqsiPFEGPIIPrevFNVIGFPDEr-fFIFNDDLDFAIRAQRAGFsikc 215 Escherichia coli
ABL63461  141 npfymnpkrl---tvlnyynnrhkdvhsafkihgvPFEGPLISkkvIDCIGFPNPd-fFIFYDDLDFSLRARKKGYt--- 213 Salmonella enterica
AAK68916  133 yskfgy-----------wqeksfnngkkfcainvgCFEGMFVSksiVNKIGFPDKr-fFIAEDDTIYGFAASFYTNvi-l 199 Bacteroides fragilis
Feature 1                                              
NP_784881 208 vSAAKLIHKTalpsldfk----skfvpdwrLYYGQRNRLIT 244 Lactobacillus plantarum WCFS1
NP_695276 226 vPDVILRRTReignwdiagvrqlnstsdmnRYHIMRNRGYM 266 Bifidobacterium longum NCC2705
CAI33743  228 aTKAQLHRQLavkvdpsev--kkvepynwrNYYKIRNNIIF 266 Streptococcus pneumoniae
AAC98409  210 sPELIFHHDVsiqgki--------ispewkVYYLCRNLILA 242 Klebsiella pneumoniae
AAN05124  221 ePGVRFEHDLtsfqgegavq-rgrltplwkVYYYHRNLLIL 260 Ruegeria sp. PR1b
YP_922601 218 vRDAVLVRQLpfdqqh--------dlsgwkGYFMYRNLFVV 250 Nocardioides sp. JS614
EAY57453  236 lRDPRINKKKiyqvenn-------pigdrsIYYGMRNTFLM 269 Leptospirillum sp. Group II UBA
ABF01012  216 iTNAKIVRKIpfvqsv--------alktwkGYFMFRNYFRV 248 Escherichia coli
ABL63461  214 iECVPIARATrllynnqa-----ndldswkGYFMLRNLFYI 249 Salmonella enterica
AAK68916  200 vSDAIMVRARrssdrs---------vspmyTYYACRNFHLV 231 Bacteroides fragilis

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