Conserved Protein Domain Family
GT2_BcE_like

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cd04183: GT2_BcE_like 
GT2_BcbE_like is likely involved in the biosynthesis of the polysaccharide capsule.
GT2_BcbE_like: The bcbE gene is one of the genes in the capsule biosynthetic locus of Pasteurella multocida. Its deducted product is likely involved in the biosynthesis of the polysaccharide capsule, which is found on surface of a wide range of bacteria. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
Statistics
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PSSM-Id: 133026
View PSSM: cd04183
Aligned: 28 rows
Threshold Bit Score: 214.04
Threshold Setting Gi: 57167258
Created: 3-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Ligand binding
Feature 1:Ligand binding site
Evidence:
  • Comment:Predicted ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           # #                                                                          
NP_790553      4 IIVPMAGAGSRFAVAGYTDPKPLIPVHGVPMIKVVIDNLTpdc--phRFIFICQaeqvaayglrekln--awapgcgive 79  Pseudomonas syr...
AAZ60114       4 IVITMAGRGSRFYAAGYKVPKYEIVAHDRSLFEWSMRSLKnflseesRIFFVCLaenrstdyvraecarlgiegvvefle 83  Ralstonia eutro...
ABH02988       6 ILFPMGGLGQRFRDQGYDLPKPLIAVDGEPMVLRALRSFDglv-gdlKIIFIVRqdaqtdhglaeslv--dyvpgatcvl 82  Spirochaeta aur...
YP_525899     10 VVITMAGQGSRFYKAGYTQPKYAIEAHGRTLFEWSMLSLKniinadsRLIFVCLqehnattfvkercl-algysdvhive 88  Saccharophagus ...
ZP_02064770    6 IIMPMAGEGSRFLKEGWMVPKPLIQLHGDPLFIRAINSLDisd-iemKYSFIVRqehidkydidkmir--dylpvanvys 82  Bacteroides ova...
YP_001011716   5 LVIPMSGIGKRFKDAGYTTPKPLIKIRGKEIINHVVNMFGei----eRVIFICNeehlhdkklnlskilsnlhpkttvvs 80  Prochlorococcus...
YP_001371289   5 LVIPMSGQGSRFARVGYTDPKPLIKIDDHPMIEWVLRMFPge----eEPLFICRrehientamaqilt--dlrpngriav 78  Ochrobactrum an...
CAL54472      58 IIIPACGKGERFRAAGYDVAKPLIKVCGQPMIDCVVQALHtnd-aldEYVVIINfdandinh--------------pvik 122 Ostreococcus tauri
EDK88889       8 LIMPMAGGGTRFKNNKINIPKPLIEINDKPFFFWAAQSILkfv-eikSLIFVVLkehiekynidkkil--eyypnakiqi 84  Fusobacterium n...
YP_061365    260 IVLPMAELGQRFRATSETQPKPLIEVDGGPMFRKALDSLTaag-irgDVTAIIRaelqrdhglgtalr--aaspdlrvve 336 Leifsonia xyli ...
Feature 1                                       #                                                
NP_790553     80 lggLTGGAACTVYAARhlin-ydqQVMIANSDQYVDVdinaylh------amnecdaAGLIMTmk-----asDPKWSFVG 147 Pseudomonas syr...
AAZ60114      84 lntITDGQATSAYVCRdawe-qeaPLLIYNIDTYVNPralrptd-------iregsqGWVPCFka------pGDHWSFVK 149 Ralstonia eutro...
ABH02988      83 lagNTRGAVETCLVAAnlid-tdtPLVVMDCDLAFRSreyfsrlsr---fgspdggdGLLLSFps------qSPRYSYAQ 152 Spirochaeta aur...
YP_525899     89 iqaLTDGQATSALLSHhlwi-pntPLLIYNIDTYVQPsaltlsd-------mkpgsqGWVPCFqv------pGDHWSFVK 154 Saccharophagus ...
ZP_02064770   83 vlkTTRGAVETCLLAEqgid-kddAIIVMDCDLEFRSlnfvaiikeilsktieevdgGALVSFqs------nMSKYSYAQ 155 Bacteroides ova...
YP_001011716  81 ikpHKKGPIHAVLEAEsile-slkPTIVNYCDFNSFFnfpnfinh-----lkkdqpdGCVFTYtgfhphmlkNTNYAYVK 154 Prochlorococcus...
YP_001371289  79 tegAKLGPVAALMAAAdeid-ndrPVLVSYCDYYMRWdydafka------amavddyLGAVPCyk-----gfHPHLLPVK 146 Ochrobactrum an...
CAL54472     123 ldrETAGAAETVLLALqahesgdvPMLLVDCDAIYHGdilerfra----leaqnvvrAAVLSFredasalssKPKYSYVK 198 Ostreococcus tauri
EDK88889      85 innILNGAVFTCLEGIklid-nddPILFNDCDHAFLSelfykycm----khnfsdidGALLTFys------dEERYSYIA 153 Fusobacterium n...
YP_061365    337 laaPTGGAAETVLAAPldp---erPLLIMDCDIAFESpgyasela-----rataggaDGVLLSfp-----ssDPRYSFAA 403 Leifsonia xyli ...
Feature 1                                                                                        
NP_790553    148 FDSQghi------------nrvVEKEVISDEATVGIYNFRsggqLVSAIeam-vlKDLRVNGEFYVAPAYNELIEQGAKV 214 Pseudomonas syr...
AAZ60114     150 LNDNgwa------------advVEKQRISENASVGLYWFAkagdYVTAYqdyyarPEHLVNGERYVAPLYRELLRRGGKI 217 Ralstonia eutro...
ABH02988     153 IDASgrv------------vdtAEKVVISQNALAGAYGFRsgrlFREYAerlvtrPLNSEMREYYLSFLFREMVGAGLTV 220 Spirochaeta aur...
YP_525899    155 LGEDgwa------------tdcAEKTRISDYASIGLYWFAcgeiYADAYqkffsdPANLVNGERYIAPLYKQLLADGKKV 222 Saccharophagus ...
ZP_02064770  156 IDENnnv------------lrtAEKEVISNHALCGAYFFSkaegFLSAAyhl-lnEVNFSKSEFYVSLLYNYLLQKGETV 222 Bacteroides ova...
YP_001011716 155 KYKNsvvdi--------qekkpFTENPMNEEVSSGTYYFKsaklMLKYFkka-ilLDLKVNGEFYVSMAYKPMIKDGLKI 225 Prochlorococcus...
YP_001371289 147 NLYAscrvdaqgnlieirekysFEADKTKALHSPGIYYFHsgglMKKYCtrl-mdMGDSLNGEYYVSMVYNHLIRDGLRV 225 Ochrobactrum an...
CAL54472     199 VDEKsdv------------mqiAEKLRVGPLANTGAYWFAssaeFVRLAriv-ieEGRFQHGEAYVSCVIDEYLRQNKTV 265 Ostreococcus tauri
EDK88889     154 LDEKnnv------------ietMEKKVISNKAICGAYYFKnkdiFKTAVke---yLDNCIYDEYFISGLYNVMIKNNLLI 218 Fusobacterium n...
YP_061365    404 TDDNgrv------------vrtAEKVAISRNALMGVYFFRrageFQECArevveaAQAGDVTESYLSLVYNRMLSRGSTV 471 Leifsonia xyli ...
Feature 1                              
NP_790553    215 IHYsigaeghGMYGLGIPVDLN 236 Pseudomonas syringae pv. tomato str. DC3000
AAZ60114     218 SIVdlp--veDVHVLGTPAELD 237 Ralstonia eutropha JMP134
ABH02988     221 HLAka----dEYHSFGTPEELA 238 Spirochaeta aurantia
YP_525899    223 SIAdlp--vtSVHVIGTPAELD 242 Saccharophagus degradans 2-40
ZP_02064770  223 QLAei----eEYYSYGTPEELG 240 Bacteroides ovatus ATCC 8483
YP_001011716 226 KTFli----nYFMQWGTPSDLE 243 Prochlorococcus marinus str. MIT 9515
YP_001371289 226 AVPeg---isHFCQWGTPEDLD 244 Ochrobactrum anthropi ATCC 49188
CAL54472     266 RAViin--edEYSNIGTPDCLE 285 Ostreococcus tauri
EDK88889     219 KYFpt----dLHISFGTPEEYE 236 Fusobacterium nucleatum subsp. polymorphum ATCC 10953
YP_061365    472 RLAr-----gTFYCFGTPEELA 488 Leifsonia xyli subsp. xyli str. CTCB07

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