Conserved Protein Domain Family
GT_2_like_f

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cd04182: GT_2_like_f 
GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function.
GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
Statistics
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PSSM-Id: 133025
View PSSM: cd04182
Aligned: 115 rows
Threshold Bit Score: 122.284
Threshold Setting Gi: 86159526
Created: 15-Aug-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Ligand bindingmetal binding
Feature 1:Ligand binding site
Evidence:
  • Comment:Predicted ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1          # #                                                                        
NP_343785   3 IGVIILAAGEGKRFGGDKLLAKi---------DNTPIIMRTIRIYGd--lEKIIIVGKYVNEMLPLLMDqivi------- 64  Sulfolobus solfata...
NP_214885   6 ITGVVLAAGRSNRLGTPKQLLPy---------RDTTVLGATLDVARqagfDQLILTLGGAASAVRAAMAldgtd----vv 72  Mycobacterium tube...
CAG36452    8 VVGIILAADRPERMGENKFLLPf---------RNKPMLQQVIDAAQastlQKLILVLPPESQSLLKHVDtgece----vv 74  Desulfotalea psych...
YP_177236   3 TVAICLAAGQSARMGENKLALPl---------LETTVGSASLKTALgtdvAKIVVVIGEKYGHTSWLDPklladrrimlv 73  Bacillus clausii K...
Q46810      4 IDCIITAAGLSSRMGQWKMMLPw---------EQGTILDTSIKNALqf-cSRIILVTGYRGNELHERYAnqsnit---ii 70  Escherichia coli
YP_856693  28 CDCLITAAGLSSRMGAWKLMLPy---------RQSTILDESLKNALvl-cDRVILVVGHRADELISRYAnhprir---lv 94  Aeromonas hydrophi...
YP_591723   7 FCGVILSAGASSRMGRDKALLPwpadlvhpttWRQTFLGAAIDMLRphtdLVIVVAGANERAITPIIYAagafl-----v 81  Acidobacteria bact...
YP_390035  46 IGGIILAAGESSRMGRCKAILPl---------GGSTVLEQTALALAaavtGPVVVVCGHHGDAVRAEARrcglt----av 112 Desulfovibrio desu...
NP_951264   5 VAALLLAAGRSIRMGRCKQLLPl---------GNTTVLGRCLDTLRrggvGEIAVVVSADGEQVARAAAghgvr----vv 71  Geobacter sulfurre...
ABB31078    3 VAAILLAAGKSQRMGLCKQLLQl---------ADRPAVAHCLDTLTavglQEIIVVVSPGGDEVAAAVSrypvv----va 69  Geobacter metallir...
Feature 1                                       #                                             
NP_343785  65 ynpFWNEGISTSLKLGLRFfk---dyDAVLVALGDMpFVTKEDVNKIINtfk---pncKAVIPTHkg---eRGNPVLISk 135 Sulfolobus solfata...
NP_214885  73 vveDVERGCAASLRVALARvhp--raTGIVLMLGDQpQVAPATLRRIIDvgp---ateIMVCRYAd----gVGHPFWFSr 143 Mycobacterium tube...
CAG36452   75 ichDQAEGQLQFLQAGLKClacsediNGCMVIPGNLpLLNEKTIDYLIDaysq--dkeSWIAPTQqd---mRGDPIIIPf 149 Desulfotalea psych...
YP_177236  74 ccrKAAEGQAESLKCGLEVaga-lgaSAVLILLADQpFLPASVIKSVLAtakr-rpdaTSVSACYkg---kQRPPALFRq 148 Bacillus clausii K...
Q46810     71 hnpDYAQGLLTSVKAAVPAvq----tEHCFLTHGDMpTLTIDIFRKIWSlr-----ndGAILPLHng---iPGHPILVSk 138 Escherichia coli
YP_856693  95 hnhDYAQGLGSSIRAGLAAcs----sDHLFVSHGDLpCIPPEVYRTLWQar-----gdETLFPSYqg---eAGHPVLLPr 162 Aeromonas hydrophi...
YP_591723  82 tnpNPERGQFSSLQIGLQEvln-rgrDAAMVALVDRpPVQPKTVEALRAafiaapdniWSVVPQFeg---kHGHPYVIGr 157 Acidobacteria bact...
YP_390035 113 tnpHPENGMFSSVQCGIQAivs--hvDAAFILPVDTpLVRASTCMLLAAsfvr--qghAVTLPVAsphrsrTGHPPLLRa 188 Desulfovibrio desu...
NP_951264  72 vnpDREGDMASSVRAGRDAfgs--avGGVIVSLCDQpLVAAGTVARLRDrhat-epgrIIIPTHGg----rRGHPLLFPl 144 Geobacter sulfurre...
ABB31078   70 vneSDSCDMADSARTGLARlis--dpTGVLVALADHpLVRPDTVRALVNrhge--epdAILIPVHdg---aKGHPTLFPa 142 Geobacter metallir...
Feature 1                                                      
NP_343785 136 slfNEIEKLrgdVGARVILNKIkieelc--fiecsEGVLIDIDKKEDLM 182 Sulfolobus solfataricus P2
NP_214885 144 tvfGELARLhgdKGVWKLVHSGrhpvr---elavdGCVPLDVDTWDDYR 189 Mycobacterium tuberculosis H37Rv
CAG36452  150 swwEKVAQLegcLETRDLLGQAslrlrl--ikmqdIGPFIKINTRAEYQ 196 Desulfotalea psychrophila LSv54
YP_177236 149 slfVKLHALagdEGARAVLRKDkssla---vpvadASAFFDIDTKEDYQ 194 Bacillus clausii KSM-K16
Q46810    139 pclMQAIQRpnvTNMRQALLMGdhysv----eienAEIILDIDTPDDFI 183 Escherichia coli
YP_856693 163 alvRALAAApaqGSVRRWLLAHphrfi----evqsAAILQDVDTPERYQ 207 Aeromonas hydrophila subsp. hydrophila ATCC 7966
YP_591723 158 emiEAFLRApadATARDVEHAHedhify--qpvndPGVCSNIDTPADYQ 204 Acidobacteria bacterium Ellin345
YP_390035 189 dvlRSVLRHdgkDGLRAVIRAFadlgmnttvpvadEGCLRDMDTPEAYR 237 Desulfovibrio desulfuricans G20
NP_951264 145 ---PVLAELedgLTLRDLVVCDparvcc--vavadPGILIDMDTPEDYR 188 Geobacter sulfurreducens PCA
ABB31078  143 ailQEIGQV---ATLRDIIGRHrdkvrl--vpvadEGVVMDMDVWEDYL 186 Geobacter metallireducens GS-15

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