Conserved Protein Domain Family
CLECT_VCBS

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cd03603: CLECT_VCBS 
A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins
CLECT_VCBS: A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins. Many CTLDs are calcium-dependent carbohydrate binding modules; other CTLDs bind protein ligands, lipids, and inorganic surfaces including CaCO3 and ice. Bacterial CTLDs within this group are functionally uncharacterized. Animal C-type lectins are involved in such functions as extracellular matrix organization, endocytosis, complement activation, pathogen recognition, and cell-cell interactions. CTLDs may bind a variety of carbohydrate ligands including mannose, N-acetylglucosamine, galactose, N-acetylgalactosamine, and fucose. CTLDs associate with each other through several different surfaces to form dimers, trimers, or tetramers from which ligand-binding sites project in different orientations. In some CTLDs a loop extends to the adjoining domain to form a loop-swapped dimer.
Statistics
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PSSM-Id: 153073
View PSSM: cd03603
Aligned: 28 rows
Threshold Bit Score: 90.5616
Threshold Setting Gi: 32471540
Created: 22-Mar-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
ligand binding
Feature 1:ligand binding surface [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
ABB28288    2612 HYYTLTdraKSWQDAEASAVALgGHLVSINDATEQAWLQSmldg------rygNVWIGLsdaa---------------ae 2670 Chlorobium chl...
NP_894667    174 SFYTIVd-gPSWVEAEANAVKLgGHLVTINDEEENKWLAEnfd--------yiGKWIGLtdsa---------------he 229  Prochlorococcu...
ZP_01090800  664 SYYKSVe-kLALNDAQRLAKSYqGRLLTISSEQEQQFILEltg--------rqNTWMSAwcnl---------------kv 719  Blastopirellul...
ZP_01090800 1221 HHYYLSpekMSLAGAQRLAADMqGRLLTVSSAEEDEWIRQklp-------nniALWTAGwrrn---------------ve 1278 Blastopirellul...
ZP_01124569 1122 SAYVVVq-gPTWEEAEANAQKLgGHLVTINDAEENDWILNtfrkd----ftngAGFIGYsdtk---------------ie 1181 Synechococcus ...
ZP_01124569 2385 SAYVIVe-gPTWKDAQENAEKLgGNLVTINDAEENYWLATnsyfes--pgnfvFYGIGLtdee---------------ke 2446 Synechococcus ...
ZP_01124569  995 SLYTIVd-gPSWTSAETNAKKLgGHLTQINDQYENDWIYSnlilatniqdtyeGAYIGLtksd---------------et 1058 Synechococcus ...
ZP_00371937   51 HYYTATvkkMTFDGAKKLAKDSgGYLAIPNSKTENDFLVSlvk-------ganFAWIGIhdsnytqnfckegsagciyds 123  Campylobacter ...
NP_870667    288 SQYKSRg-rNTKIEAEQLAHESgGHLLAINSAEEQSLFEPie----------sETWIGIslgeh-------------esv 343  Rhodopirellula...
ZP_00518842   12 QTYLITdnvMTWEEAETTAQELgGHLVAINSEAEQEFIENnilig---qyerlPLWIGIndve---------------ne 73   Crocosphaera w...
Feature 1                                                #   # #                    # ####       
ABB28288    2671 atWQLTDGtt-sTYANWasnep-------------yyqweSNYDYAYmns---------------ngQWGASYNt----- 2716 Chlorobium chl...
NP_894667    230 gvFKWASGas-vDFTNWaa--------------------dQPDNYHGiqhyaifsg--hwnykgikyGWDDLQDmkn--- 283  Prochlorococcu...
ZP_01090800  720 keWRDERNrkltFFSKWgr--------------------nQPDNNGAspeiflgi-----fthpdsfGWNDFAPd----- 769  Blastopirellul...
ZP_01090800 1279 nqWYDERNrripYMGSWet--------------------eGGYDYRPeeqflalrttldetsrlirlKRLTLPPq----- 1333 Blastopirellul...
ZP_01124569 1182 gqWIWSSGea-tTYTNWdagn---------------psnsGGLENVGtiqf-------------gdgSWNDVATnywnw- 1231 Synechococcus ...
ZP_01124569 2447 gdWAWKDAsk-sTFRSWdqsngdglp-----epnspndgiSNYAYIGrgfnndslyk-tetsgleegSWYDDGNrpsp-- 2517 Synechococcus ...
ZP_01124569 1059 rtWGWSNGvp-sNYFNWaegtpn------------geyvpENYGVINie-----------------gFWDDWTNqq---- 1104 Synechococcus ...
ZP_00371937  124 srFKTIKGea-lSYKNFaskqpdnllkqydivngkekvspLGEHWVAmaa--------------psgQWADLGNhfgt-- 186  Campylobacter ...
NP_870667    344 dsLRWSSGee-iTYNNWregepa-----------lhshesRGDGVMDqs-----------------gKWALKQVfs---- 390  Rhodopirellula...
ZP_00518842   74 geYVWTTGet-lDFTNWneeq---------------pndsGDYGTINwhhsrf--------dtnikgTWNDVPLegtvgf 129  Crocosphaera w...
Feature 1             ###      
ABB28288    2717 -----NSMRGVIEL 2725 Chlorobium chlorochromatii CaD3
NP_894667    284 ---deNVNQGIAEI 294  Prochlorococcus marinus str. MIT 9313
ZP_01090800  770 -----AKCFAVIEW 778  Blastopirellula marina DSM 3645
ZP_01090800 1334 -----PALSVVIEW 1342 Blastopirellula marina DSM 3645
ZP_01124569 1232 -fgqkGEIKGIAEI 1244 Synechococcus sp. WH 7805
ZP_01124569 2518 -afngIKVFGIAEI 2530 Synechococcus sp. WH 7805
ZP_01124569 1105 ----gNISKGIAEI 1114 Synechococcus sp. WH 7805
ZP_00371937  187 -nenpIKNYALLEF 199  Campylobacter upsaliensis RM3195
NP_870667    391 ----yISKTTIIEL 400  Rhodopirellula baltica SH 1
ZP_00518842  130 egftdGLYFGLIEL 143  Crocosphaera watsonii WH 8501

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