1BXN,1GK8,8RUC,1BWV,1RSC


Conserved Protein Domain Family
RuBisCO_small

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cd03527: RuBisCO_small 
Click on image for an interactive view with Cn3D
Ribulose bisphosphate carboxylase/oxygenase (Rubisco), small subunit. Rubisco is a bifunctional enzyme catalyzes the initial steps of two opposing metabolic pathways: photosynthetic carbon fixation and the competing process of photorespiration. Rubisco Form I, present in plants and green algae, is composed of eight large and eight small subunits. The nearly identical small subunits are encoded by a family of nuclear genes. After translation, the small subunits are translocated across the chloroplast membrane, where an N-terminal signal peptide is cleaved off. While the large subunits contain the catalytic activities, it has been shown that the small subunits are important for catalysis by enhancing the catalytic rate through inducing conformational changes in the large subunits.
Statistics
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PSSM-Id: 239603
Aligned: 27 rows
Threshold Bit Score: 141.24
Created: 28-Mar-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
multimerization
Conserved site includes 21 residues -Click on image for an interactive view with Cn3D
Feature 1:multimerization interface [polypeptide binding site]
Evidence:
  • Comment:small subunits makes contacts to two neighboring large catalytic subunit dimers and to other small subunits
  • Structure:1GK8; Chlamydomonas Rubisco
  • Structure:8RUC; spinach Rubisco
  • Structure:1BWV; Galdiera Rubisco

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         ## ##### # #       #  #          #                          ### ##              
1BXN_I          3 ITQGTFSFLPELTDEQITKQLEYCLNQGWAVGLEYTDdph------------------prNTYWEMFGLPMFDLRDAAGI 64   Ralstonia eut...
1GK8_I         10 KMFETFSYLPPLTDEQIAAQVDYIVANGWIPCLEFAEadkayvsnesairfgsvsclyydNRYWTMWKLPMFGCRDPMQV 89   Chlamydomonas...
132143        863 KKFETFSYLPPLSDAQIAKQVDMIIAKGLSPCLEFAApensfiandntvrfsgtaagyydNRYWTMWKLPMFGCTDASQV 942  Euglena gracilis
8RUC_I         10 KKYETLSYLPPLTTDQLARQVDYLLNNKWVPCLEFETdhgfvyreh------hnspgyydGRYWTMWKLPMFGCTDPAQV 83   spinach
132147         57 KKFETLSYLPPLSTDDLLKQVDYLLRNGWIPCLEFSKvgfvyren-------stspcyydGRYWTMWKLPMFGCNDATQV 129  Zea mays
BAD42333       52 KFFETFSFLPPLSDSEITKQVDYIVRNGWTPCLEFSDpegayigdtntvrlqgtsagyqdNRYWSMWKLPMFGCTDGSQV 131  Nannochloris ...
BAD38061       60 RRYEAMSYLPPLSAKSISKEIEFIMSKGWVPCLEFDKegeihrsn-------srmpgyydGRYWTLWKLPMFGCSDAAAV 132  Japanese rice
BAA83481      101 PKFETFSYLPPLTDDQIAKQVDYMIQQNLIPCIEFDTvgsvsrtnfs----gagssgyydGRYWTMWKLPMFGCTDSSQV 176  Physcomitrell...
1RSC_M         10 RRFETFSYLPPLSDRQIAAQIEYMIEQGFHPLIEFNEhsn------------------peEFYWTMWKLPLFDCKSPQQV 71   Synechococcus...
NP_001031981   65 KKFETLSYLPDLSDVELAKEVDYLLRNKWIPCVEFELehgnt-------------pgyydGRYWTMWKLPLFGCTDSAQV 131  thale cress
Feature 1                   #                # ##        
1BXN_I         65 LMEINNARNTFPNHYIRVTAFDSthtvESVVMSFIVNRP 103  Ralstonia eutropha
1GK8_I         90 LREIVACTKAFPDAYVRLVAFDNq--kQVQIMGFLVQRP 126  Chlamydomonas reinhardtii
132143        943 LREISECRRAYPQCYVRLAFDSVk---QVQVISFVVQRP 978  Euglena gracilis
8RUC_I         84 LNELEECKKEYPNAFIRIIGFDSn--rEVQCISFIAYKP 120  spinach
132147        130 YKELQEAIKSYPDAFHRVIGFDNi--kQTQCVSFIAYKP 166  Zea mays
BAD42333      132 LKEIAGCTKAFPGAYIRLVAFDNq--kQVQCTGFLVHRP 168  Nannochloris bacillaris
BAD38061      133 LREVEECRREYPDAFIRLIAFDSs--rQCQCMSFVVHKP 169  Japanese rice
BAA83481      177 LREIQECKSQFPSCWVRVLGFDSk--kQVQICGFLVSRP 213  Physcomitrella patens
1RSC_M         72 LDEVRECRSEYGDCYIRVAGFDNi--kECQTVSFIVHRP 108  Synechococcus elongatus PCC 6301
NP_001031981  132 LKEVEECKKEYPGAFIRIIGFDNt--rQVQCISFIAYKP 168  thale cress

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