1Q6W


Conserved Protein Domain Family
MaoC_like
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cd03446: MaoC_like 
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MoaC_like Similar to the MaoC (monoamine oxidase C) dehydratase regulatory protein but without the N-terminal PutA domain. This protein family has a hot-dog fold similar to that of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.
Links
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Statistics
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PSSM-Id: 239530
Aligned: 12 rows
Threshold Bit Score: 196.371
Created: 4-Apr-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative activeputativehomodimer
Conserved site includes 7 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on the active sites of (R)-hydratase and the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                 #    # #  #              #  ##                        
1Q6W_A       14 YFESIQIGEKIEGLPRTVTETDIWTFAYLTADFFPLHTDVEFAKKTIFGKPIAQGXLVLSIALGXVDQVilsnydvssvi 93  Archaeoglobus fu...
NP_071138     5 YFEDFEIGMKVESAARTVTEADIVMFASLSGDWNPIHTDAEFAKKTIFGQRVAHGLLTLSVVAGLLVRLglte---rtiv 81  Archaeoglobus fu...
NP_878941    11 TFDEIEVGKVFRSGGRTITETDVVNFCALTGNWIEIHSNVQYASKTRFGKRLVQGSLTYSIVTGLIQFGlg-------iq 83  Bordetella pertu...
NP_069036     5 YFEDFQEGMELETVGRTVTEADIVMFAALTGDWNPIHVDAEYAKTTIFGQRIAHGTLTFSIMTGLLMRLgfle---etvv 81  Archaeoglobus fu...
ABB06535     11 PLDELEIGTKFRSNGRTVTESDVVMFCMFTGNWIEIHSNKEYASKTRWGERIVQGQLTFSLISGLLQFGpa-------iq 83  Burkholderia sp....
BAD71815      4 YFEDFEVGQRFVTAGRTVTEADVVNFAGVSGDYNPIHTDAEFAKSTPFGQRIAHGLLVLSMLTGLRQRTgatd---gtli 80  Thermus thermoph...
BAD76405      6 PFEQYALGERHRSRGRTITEADIVQFAGVSGDFYPLHMDGEYAKRTPFGERIAHGMLTLSAATGLWMMEpgv------vl 79  Geobacillus kaus...
NP_943032     6 YFEDFLRGQVFESTGRTITETDLTMFSMLSGDWNPIHADAEFARGTRFGQRVVHGALGIALATGMLHQLgvfd---ksav 82  Cupriavidus necator
CAI49470      8 VFEHTDIGDTDTTHGRTVTEADVTNFAGVSGDFNHLHTDEERMADSMFGERIAHGMFVLSAATGLLWQTrtpee-reavv 86  Natronomonas pha...
YP_136556     4 EFDTVDVGDSFTTSGRTITEADVVNFAGVSGDFNHLHTNAERMADSGYGERIAHGALVFSVVTGLLWQArdeae-krhmv 82  Haloarcula maris...
ZP_00656609   8 SFDDFEAGQVFTGQGRTITESDLVWFASWSWDTNPPHTDAVHMASSRFGERIAHGLLGMSVAMGLASRLgvfe---scsi 84  Nocardioides sp....
AAV48420      9 HFEDFEEGQEFISVGRTVTESDFVMHSALSGDWTELHTNKEYAEEQEFGERIAHGPMTFVQATGFVYRTgive---rtaf 85  Haloarcula maris...

Feature 1                                                                       
1Q6W_A       94 AFFGIKDVRFLRPVFIGDTIAASAEVVEKqdfd--eksGVVTYKLEVKNQRGELVLTALYSALI 155 Archaeoglobus fulgidus
NP_071138    82 AFYGIDKLRFTNPVFIGDTIRAVLEVVGKedke-gkpyGVVVYDIKGVNQRGEVVITYTSRAAI 144 Archaeoglobus fulgidus DSM 4304
NP_878941    84 ANYGIDNMRFLAPVSIGDTIYAVCEVMRKkekd--ekyGVITFFMKAVNQDGTVVQKGEWSLLM 145 Bordetella pertussis
NP_069036    82 AFYGVDRLRFTNPVFIGDTIKARAKVVEKqdr---gqfGVVKIEASVVKQTGDVVLNCILRVAV 142 Archaeoglobus fulgidus DSM 4304
ABB06535     84 ANYGVDKMRFLNPVKIGDTVYASAEVIAKkekd--dkfGVGTMLIQAYNQRGEVLQRSEWSLLM 145 Burkholderia sp. 383
BAD71815     81 AWLEIRNYRFLKPVLIGDTVHGETEIVEKrets-kpdrGIVVQRVRVLNQRGEVVQEGEFVTMI 143 Thermus thermophilus HB8
BAD76405     80 AFYGIDSLRFVRPVKIGDTIYVESEVKRLterg--eeaGLVTVHQRIVNQREETVVDAVVHVLV 141 Geobacillus kaustophilus HTA426
NP_943032    83 AMMSLQNWTFAAPIFVGQTLRLRMEILETeagt-skrvGRVNRRLQLIDQTGGVIQDGTTDVLV 145 Cupriavidus necator
CAI49470     87 AFYGIDNLRFRQPVYIGDTIHVETEVVDTeakpdgpgnGTVTTAIEVVNQRDQTVISCEMTSLL 150 Natronomonas pharaonis DSM 2160
YP_136556    83 AFYGIDRLRFIKPVFLGETIHVEAEIVDTerrdhpvatGVVRTEVTAVNQADDAVFSAEFLTLR 146 Haloarcula marismortui ATCC 43049
ZP_00656609  85 ALLGVDDWRFHAPVVVGDTVRVRVTILGTrvtt-agdsGVLERRFELINQRAEVVQSGSIPLLV 147 Nocardioides sp. JS614
AAV48420     86 AFLGMNYMDLPNPVHIGDTLQLEIVVDNTkevg-rddaGLVVLDTEMENQDGTVVFEGDMKFLI 148 Haloarcula marismortui ATCC 43049

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