1D2T,1IDU,1QHB,1QI9


Conserved Protein Domain Family
PAP2_like_1
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cd03380: PAP2_like_1 
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PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium chloroperoxidases and vanadium bromoperoxidases.
Links
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Statistics
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PSSM-Id: 239475
Aligned: 55 rows
Threshold Bit Score: 85.1781
Created: 28-Dec-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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active site
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:1D2T_A: bound sulfate marks the phosphate binding site of Escherichia blattae non-specific acid phosphatase
  • Structure:1IDU_A: Curvularia inaequalis, chloroperoxidase, vanadate is bound at the active site
  • Citation:PMID 9165086
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                        
1D2T_A         7 GNDTttkpdlyylknseAINslalLPPPPAvg--------siAFLNDQAMYEQGrll--------rntERGKLAAEDAnl 70   Escherichia bl...
BAC68458     203 RLRPlll-------tspDQF----RPGGPPals-------saRYAEDVNEVKTMgaksg----ssrtaPQTETALFFGgn 260  Streptomyces a...
ZP_00400772  238 FVIPlta-------pspGAR----RAPPPPnlr-------saRYADALAEVREYgrkes----asrtpAMTDVVQFWTes 295  Anaeromyxobact...
ZP_00573511  199 NLRPfli-------psaSMF----RSAGPPalt-------seRYARDLNEVKTIgavns----ttrtlDQTQAAIWWHdr 256  Frankia sp. EA...
CAJ34369     210 LARPfll-------graDRF----RPPPPPalg-------taPYRRALDEVRRLggev------sertEAQSDLAWLDpl 265  Micromonospora...
ABB74230    1450 TVTPfal-------saaNQF----RPPAPPald-------ssEYAQSVEEVRSVgsans----ttrtaDQTEQAQFWAdg 1507 Nitrosospira m...
ABB74996     180 QIRPwlm-------dnpAQF----RPGPPPqle-------seLWARDYNEVKALggkhs-----qrtaAQTEIARFWEev 236  Nitrosospira m...
BAB72630     171 KVKTfsk-------apiKQF----RPTRPAgfktkkallaslEYAAQVNEVKRLgadns----tertqEQTDIALFWAnd 235  Nostoc sp. PCC...
CAD72609     362 DVDTfai-------sdaDAF----TPESPPdlt-------seEYAASYNEVKELgavds----ttrtaDQTEAGIFWAyd 419  Rhodopirellula...
ZP_00840701  287 DVQPfvi-------knvPTF----RPPPPPstd-------saEYARDFEEVRKLggentersrsersaDQTLIGTFWAyd 348  Rhodopseudomon...

Feature 1                                                                     #        #         
1D2T_A        71 s-------sggVANAFSgafgsp----------itekdaPALHKLLTNMIEDAGdlaTRSAKD--HYMRIRPFAFy---- 127  Escherichia bl...
BAC68458     261 l-------vvqFQEAFRdytarhh---------lgiaetARLFVAGNASATDAVv-aTWDAKL--HYGFWRPITAihlad 321  Streptomyces a...
ZP_00400772  296 g-------ftlWQRNTRdlvaarn---------ldeletARALAAIGVAGGEAMl-aCFESKY--HYLGWRPFQAiqrad 356  Anaeromyxobact...
ZP_00573511  257 h-------lgeWEIKRQlatgrr----------lstlqtARMFAMVDLTEADATt-aCFNEKA--AWTSWRPVTAiqlad 316  Frankia sp. EA...
CAJ34369     266 ---------sqYVPVLRllvgdsa---------rsrrskVRLLAALGAAIVDSSi-aTFEAKY--ALLHWRPVTAirdad 324  Micromonospora...
ABB74230    1508 mgsy--tppghWNQIAEeiaraqg---------nslsanARLFAMLNIALADAAi-aCWDAKY--TYGLWRPETAinnad 1573 Nitrosospira m...
ABB74996     237 m-------ppiYHGVIRsvaeapg---------reitrnARLFAAATQASTDALi-aVFDAKY--HYGFWRPVTAirngd 297  Nitrosospira m...
BAB72630     236 ldgt-ykppghLFSITQivsklkg---------lsfyenARLFALVGLGLGDAGi-lAWDAKYntDLDLWRPESAiqlah 304  Nostoc sp. PCC...
CAD72609     420 rdgl-gtpltlFNDILEtvavqeg---------ntfeenAALFAQASVAMADAGv-vAWTTKF--GEELWRPVTAiqegd 486  Rhodopirellula...
ZP_00840701  349 gtaflcapprlYNQVIRqivqqqikdgdtkdedpkllnyARLFALANIAMADAAi-aAWDAKY--HYRYWRPVVGiraaa 425  Rhodopseudomon...

Feature 1                                             ###                                        
1D2T_A       128 ------------gVSTcntt-----eqdkLSKNGSYPSGHTSIGWATALVLAEINpq----------------------- 167  Escherichia bl...
BAC68458     322 tdgnpateadpqwQPLl-----------vTPPHPDYVSGHAAVAGAVTQTLSGILgttrldlnvs--------------- 375  Streptomyces a...
ZP_00400772  357 edgnertepeplwTPLv------------RANHPEYPAGHGCYGSAMATSLRLLFgdmavtltstgs------------- 411  Anaeromyxobact...
ZP_00573511  317 tdgnpattadptwAPLl-----------vTPPHPDFTSGHTCFTTASMSTLAFFFgrddipfsay--------------- 370  Frankia sp. EA...
CAJ34369     325 tdgdprtapdptwNSFl-----------pTPPHPEYPSGHAVTAGAAEQVLSQLVgpctpmafsitfa-----------r 382  Micromonospora...
ABB74230    1574 ldnnaatikeegwKPLl-----------iTPAHPEYVSGHSTFSAAAAGILNQVFgndtsfstts--------------- 1627 Nitrosospira m...
ABB74996     298 vdgnnaterdpswLPFi-----------dTPMHPEYPCAHCIVAGAVGTVLKAEIgadpipplatt-------------- 352  Nitrosospira m...
BAB72630     305 tdgnpgtvadptwRPLspnpd----gtrfSPPFPAYISGHATFGAIHAGILRNFFgtdnvtftatsedp----------s 370  Nostoc sp. PCC...
CAD72609     487 fdgntltegdadwTALgapdgg-ddivgfTPQFPTYISGHATFGGALFGTLQEFYgtddisftvaseeleilldnpelqe 565  Rhodopirellula...
ZP_00840701  426 tdgndathadvywKALgapasnsvrgpnfTPPFPAYPSGHATFGGALFEVLRAFYpddtsfsfisdeyngq-----nkpa 500  Rhodopseudomon...

Feature 1                                  #     #   #                 
1D2T_A       168 -----------rQNEILKRGYELGQSRVICGYHWQSDVdAARVVGSAVVATLHT 210  Escherichia blattae
BAC68458     376 ---seitgttrhYEYADQFNKDMINARVWSGIHSRTADtAGCRAGNRVGAWTFT 426  Streptomyces avermitilis MA-4680
ZP_00400772  412 qvagwpqvpsrrYASLAAIPDENADARVWGGLHFRTTMeQSARWIRDVTNDALC 465  Anaeromyxobacter dehalogenans 2CP-C
ZP_00573511  371 ---sadsgttryFRGFSHAIAEVIEARVWGGIHTRSADtEGAKIGAKVTAYATR 421  Frankia sp. EAN1pec
CAJ34369     383 gdgrvvtrnyrrGTPWSTLTKENIDARVLAGVHFRYSDeVGAALGRQVARYDLN 436  Micromonospora sp. ML1
ABB74230    1628 ---ytlpgvtrsFDNFDAAAGEAGRSRVYGGIHYEFTNqAGQTLGHQVAEAVLA 1678 Nitrosospira multiformis ATCC 25196
ABB74996     353 --sraaggvmrsWKNIDEIIQEVANARIYDGVHYRNSGeVGTAMGRRIAELAVM 404  Nitrosospira multiformis ATCC 25196
BAB72630     371 argangirvtrtFNSFSAAALENGRSRVYLGVHYQWDAdAAYVSGTKLADFVSE 424  Nostoc sp. PCC 7120
CAD72609     566 ayglnlddaertFSSFSEAMAENGRSRVYLGIHFDFDDlVGQEVGQSIAAAVAS 619  Rhodopirellula baltica SH 1
ZP_00840701  501 gsdvprpevtrrFVNFRAAEDENARSRVYLGVHWQFDAdAGIAQGNQVGSFVVG 554  Rhodopseudomonas palustris HaA2

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