Conserved Protein Domain Family
CmuC_like
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cd03309: CmuC_like 
CmuC_like. Proteins similar to the putative corrinoid methyltransferase CmuC. Its function has been inferred from sequence similarity to the methyltransferases CmuA and MtaA. Mutants of Methylobacterium sp. disrupted in cmuC and purU appear deficient in some step of chloromethane metabolism.
Links
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Statistics
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PSSM-Id: 239425
Aligned: 8 rows
Threshold Bit Score: 324.755
Created: 7-Feb-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EAM95508      9 WETLKggnpDRFVKQYEFMNLim-----------eaSVTMAgfp--------apGQTskaAWGITWMWPe---gQIGPFP 66  Desulfitobacteri...
AAC83696      9 VEVMKggnpDRFVKQYEAFALmm-----------ktPITRLkp---------pvGGSivnEWGVTLSWPe---gQLGSFP 65  Acetobacterium d...
ZP_00558451  19 LETIRggnpDRFVNQYEFMDIil-----------enPVDFMap----------pGGSiktGWGITFRWPe---gQIGQFP 74  Desulfitobacteri...
CAB40739      8 AALLAgqptDRLLIDVGTSTLtarrphcrpasgdgrRYADAvmh--------lpLLAd-eELAALGSQTrrcgpSFAGAD 78  Methylobacterium...
AAW22508      7 QRAGDia-aRRMVVDIGTTSLtgvrsaa--vagarrGFASHpiy-------qttPLSa-sDCSKLGSDFqr--vGFLYDR 73  Aminobacter liss...
CAB39402      4 EPFPWlg-nKRLCIEIGCTAFtgltlgv-gsntlndGLSLSasa-------gvgLMSg-kSGASVGSAFvr--tGFAYEA 71  Methylobacterium...
ZP_00557309  36 KEAIKal-fERKPIWQVMLNMgveaapf--tppihpDYVARalvidgtfvpgvtNTTggkDLFGIEWEYv---pSARGSM 109 Desulfitobacteri...
ZP_00557371  11 LVYQHkv-pEFLPLMKDIQYIrtvep------gflhVVYEGka----------tGSNdavDWFGQNWKFe---pKIGAFN 70  Desulfitobacteri...

EAM95508     67 VHdEEHKVLKDi-tEWRKYv-QAPVIptdd---------------etwAPAIAHAQAVDRnee--fvTMMAAPGvFEMTH 127 Desulfitobacteri...
AAC83696     66 IHdKEHIVIKDi-tKWRDYv-KAPNLdypd---------------eawATAVADANAVDRndq--yvTVFVAPGlFEHVH 126 Acetobacterium d...
ZP_00558451  75 VHdEEHKVLKDi-tKWREQv-KAPEIpdtd---------------eawAAAVEHANSIDRnek--yvTAFVAPGvFEMCH 135 Desulfitobacteri...
CAB40739     79 IDpEDDVFADRdgvRWIWAdgEPAPTahplgqagfkeivrsqrevlpqIVTPSCLDQANRelv-vvaDVPSPGLlDTAFR 157 Methylobacterium...
AAW22508     74 LSeGGDEVTDAygvSWLFSdgFPAPFqhpletadwk---dvsrhprpqSPSRIQLADASRpdlltvlDPPCRDFsTPASR 150 Aminobacter liss...
CAB39402     72 VPgSEGEIVDAygaRWHRGveGSSLVqaplagadl-----haihayspATPRLWLQISDRadmfelaDAPLPGLvASCFA 146 Methylobacterium...
ZP_00557309 110 VR-PGKPFIEDa-nELKDKv-IWPDIakw----------------dwtGCQKANETYLNKtn---aiHGMLLNGwFERLI 167 Desulfitobacteri...
ZP_00557371  71 PD-ATQYIVKDi-tKWKEYv-NIPDVeei----------------dweAKFSTDAISLDRnk---fiIVKDGQGpWERAF 128 Desulfitobacteri...

EAM95508    128 HLMSmed--alMALYEep--eaMHELIDYLTEFELAYAKTVIeki--hpDALFHHDDWGsqinsflspeMFKKFFLPAYK 201 Desulfitobacteri...
AAC83696    127 YLMSmee--alMAYYEep--eaMHELIDYLVDFELRLAKEFIkhl--hpDAVFHHDDWGsqinsfispaMFEEFFEPAYK 200 Acetobacterium d...
ZP_00558451 136 HLMSmed--alMALYEep--elMHELIDYLTEYELKLAEIICrrl--kpDALFHHDDWGsqkssfispaMFEEFYLPAYK 209 Desulfitobacteri...
CAB40739    158 LRGYyel--leDMTEQwp---iANALFDQSADAIARDYEVMLralhgepDLVVYGDDLAfqsdsyiseeRFSFFLRPRMS 232 Methylobacterium...
AAW22508    151 FVTHgsswmtyRQLAHrv---gASGLGGGNHRAKLPHGARRAai---epDLIVYGDDLGfqggmylsdqDFRNFLFPRMQ 224 Aminobacter liss...
CAB39402    147 LRGGwsf--leECADRsp---iAFALLDWAEEQISSFYIQLIrslahdpNLIIYHDELGtdlssyfserDFRDLILPRMR 221 Methylobacterium...
ZP_00557309 168 AFMDfeg--avLAISDedqqdaVKEFFDKLTNLYIEICDKQLkhf-pqiDYFVIHDDWGsqkdtffspaTVREMIVPYMR 244 Desulfitobacteri...
ZP_00557371 129 SMTPiad--llCDLIIep--eaCYEFFGIIADHKIKLHNHYIkyy--kpDALCMHDDYGsgqglfmspdTWRQLIKPHLQ 202 Desulfitobacteri...

EAM95508    202 KIYGFYKangveLIVHHSDSYAanLVPFMIEMGVDIWQGVMtt--nnTPELIEKYGe------kITFMGDIDSg---YLD 270 Desulfitobacteri...
AAC83696    201 KIYGYYKengveLIIHHSDSYAanLVPSMIEMGIDIWQGVMnt--nnIPELIKQYGe------kITFMGGIHSg---LVD 269 Acetobacterium d...
ZP_00558451 210 KIYSFYKqngveLIVHHSDCYAanLVPFMIEMGIDIWQGVMtt--nnTPELIKQYGg------kISFMGDIDSg---VVD 278 Desulfitobacteri...
CAB40739    233 RIFSVIRsvtsaDILFHSCGAAlpILRKVVEMGVRVVNFEAtasgmdLATVRRALGp------nVVFHGVLDFv---ALA 303 Methylobacterium...
AAW22508    225 TLFARLRrmssaAICMHSCGAVrsIVGDLASLDVEMLNLDFyaknmiVADVRRELPssvilhapVNLASIGDAvregNNA 304 Aminobacter liss...
CAB39402    222 RILERIRsttsaPIGVFIRGSAlsALSSVAELGVAVLGVDCnargntVKVLRNLLGy------gVVLHGAADLv---ALG 292 Methylobacterium...
ZP_00557309 245 RLTDFLHfk-grYCDLHSCGNLikQVPNMIEAGFDSWNPQLmn---dIGKIYELYGd------kIIIATAPDD----LFD 310 Desulfitobacteri...
ZP_00557371 203 RIIDNVTsq-gvMYEHHCCGVMapLAEEIADMGASSWNVVHvs--nnTYACKQKFGd------kLALVGGICDg--qFLD 271 Desulfitobacteri...

EAM95508    271 LpdwqperCAEAVERACRRCgk---hYFIPCLTMGGPDSiy----pgVYAQVNQEIDR 321 Desulfitobacterium hafniense DCB-2
AAC83696    270 FptwtpeiVAEYVEKTCQENgk---lHFIPSQTSGLPIDsf----pgVYETINKEIDK 320 Acetobacterium dehalogenans
ZP_00558451 279 FptwtreiAAREAERACTNCgk---hYFIPCLTQGLGFSsf----pgVYDCVSEEIDK 329 Desulfitobacterium hafniense DCB-2
CAB40739    304 Tamr--egDRSGILQAANSIva--gwPMIAAPSDNLPASlg----saDIRRVTAFLER 353 Methylobacterium chloromethanicum
AAW22508    305 Tla---llATELAGSMPAIAap--idNIISMEALEANFRgv-----aFVRALSAGDLV 352 Aminobacter lissarensis
CAB39402    293 Ralt--dgDMRGTAILASEFae--arPAIAAPSAVLTSDad----lsAAARGSSFLSV 342 Methylobacterium chloromethanicum
ZP_00557309 311 Peta-seeEQRASAKAYAEKycnpnkPTTFSQYAQADLKimttafreELYKQSRLLYG 367 Desulfitobacterium hafniense DCB-2
ZP_00557371 272 LagmtaeeICAHVREVADKMlpg-vgTVISVKTVAHPERtkii-edeLLKYGQSFFKV 327 Desulfitobacterium hafniense DCB-2
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