Conserved Protein Domain Family
ABC_SMC5_euk
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cd03277: ABC_SMC5_euk 
ATP-binding cassette domain of eukaryotic SMC5 proteins
The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Links
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Statistics
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PSSM-Id: 213244
Aligned: 42 rows
Threshold Bit Score: 1e+06
Created: 1-Apr-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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  next features
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                      ## ###                                          
CAG07476     3 GTILRITMKNFLTYDYTEVYPGPNLNMIVGANGTGKSSIVCAICLGLAGktavlGRGDKVGLYVKRGCnkGSVEIELYKH 82   Tetraodon nigrov...
CAE59031    20 GSLLRVVFHNFLTYEHTSFIPTASLNMILGHNGSGKSSIICGICLACGGspktlGRSEKITEYIRHGCqeGYVEVVIADN 99   Caenorhabditis b...
AAK31464    20 GSLLRVVFHNFLTYEHTSFLPTASLNMILGHNGSGKSSIICGICLACGGspkslGRSERIVEYIRHGCteGYVEIAIADK 99   nematode
T15650      20 GSLLRVVFHNFLTYEHTSFLPTASLNMILGHNGSGKSSIICGICLACGGspkslGRSERIVEYIRHGCteGYVEIAIADK 99   nematode
CAD59407     8 KVCALIFIILFSTYDSVVLYPEEYLNIILGPNGTGKSAIVAGIVLGMGGnckllSRCDNVISYIKNGKdsATIRISIYRN 87   African malaria ...
EAA00424     8 KVCALIFIILFSTYDSVVLYPEEYLNIILGPNGTGKSAIVAGIVLGMGGnckllSRCDNIDSYIKNGKdsATIRISIYRN 87   Anopheles gambia...
CAD29584    14 GRIHSVYCKDFVSYSEITFHPKHYLNVLTGPNGSGKSTIVSAIILGLGGepillDRSASVADYIQSNKtsATIIVRVYGR 93   fruit fly
AAQ22436    14 GRIHSVYCKDFVSYSEITFHPKHYLNVLTGPNGSGKSTIVSAIILGLGGepillDRSASVADYIQSNKtsATIIVRVYGR 93   fruit fly
NP_730660   14 GRIHSVYCKDFVSYSEITFHPKHYLNVLTGPNGSGKSTIVSAIILGLGGepillDRSASVADYIQSNKtsATIIVRVYGR 93   fruit fly
CAG83578    70 GSILQIYMKNVMSYDECLVNFGPTLNFVIGPNGSGKSTMLAAICLAFAApitcmGKAALKAQQLIKSTk-DALEVRVVVK 148  Yarrowia lipolyt...

Feature 1                                                            #                         
CAG07476    83 GGNvvimreihvennqslwmi----ngkqrnqkaveeevrslrIQVSNLCQFLPQEKVGEFAKMSKTELLeateksvgpp 158  Tetraodon nigrov...
CAE59031   100 VKGpqtvrltirvgkapeykl----nnshatqsdindlrkhynIQIDNPCAFLAQDKVKSFSEQSSIELLkntekaasdd 175  Caenorhabditis b...
AAK31464   100 QKGpqvvrltirvgeqpkyrl----ndsattqseiadlrkhynIQIDNPCAFLAQDKVKSFSEQSSIELLrntekaasad 175  nematode
T15650     100 QKGpqvvrltirvgeqpkyrl----ndsattqseiadlrkhynIQIDNPCAFLAQDKVKSFSEQSSIELLrntekaasad 175  nematode
CAD59407    88 NERavrwfsrsfdhsakstfei---dnqtvsqqaylqqirafnIQVDNLCQFLPQDRVQDFTKMNPRELLlntqssvctp 164  African malaria ...
EAA00424    88 NERavrwfsrsfdhsakstfei---dnqtvsqqaylqqirafnIQVDNLCQFLPQDRVQDFTKMNPRELLlntqssvctp 164  Anopheles gambia...
CAD29584    94 TPNttetfrriinsnglstfsv---ndkdtskknflaavssfnIQVSNLCQFLPQDRVQDFSKMNPQELLlntmssvcde 170  fruit fly
AAQ22436    94 TPNttetfrriinsnglstfsv---ndkdtskknflaavssfnIQVSNLCQFLPQDRVQDFSKMNPQELLlntmssvcde 170  fruit fly
NP_730660   94 TPNttetfrriinsnglstfsv---ndkdtskknflaavssfnIQVSNLCQFLPQDRVQDFSKMNPQELLlntmssvcde 170  fruit fly
CAG83578   149 NFAgmpdltfkrtltrdeklgrffingksatmkevratareldIQIVSMTRFLPQDRVKDFTTMSPKELLittmedvgyq 228  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   159 emfeyhcelknfrtkerelenivkekknylekakqrheknkhdvnryyekkrhldmiellekkkpwveyettrkeiesvk 238  Tetraodon nigrov...
CAE59031   176 ldqrhrslmeqrkdsmtieelcatsekakkhledtrtkimplvenyrkkmalesklrllekkmacmefqeadeeyakeqk 255  Caenorhabditis b...
AAK31464   176 ldqqhidlmkqredstsiedkcttsenaikrledeigkimplvenyrkklalqsklrllekkmkimefekfdreykaelq 255  nematode
T15650     176 ldqqhidlmkqredstsiedkcttsenaikrledeigkimplvenyrkklalqsklrllekkmkimefekfdreykaelq 255  nematode
CAD59407   165 evqqwfeelkekrslqekstnqgaegtarvrelearlealeaqlqsmrareefqqqihvcmarkawleyeelfllysatl 244  African malaria ...
EAA00424   165 evqqwfeelkekrslqekstnqgaegtarvrelearlealeaqlqsmrareefqqqihvcmarkawleyeelfllysatl 244  Anopheles gambia...
CAD29584   171 dlinsfnslkqmrteqanvhanrekeksdlvkkqkrleqvtkcvdevqnfnsylqmtvsqykereevkqklqvysakklw 250  fruit fly
AAQ22436   171 dlinsfnslkqmrteqanvhanrekeksdlvkkqkrlehlqmtvsqykereevkqklqvysakklwvetqageakaaemk 250  fruit fly
NP_730660  171 dlinsfnslkqmrteqanvhanrekeksdlvkkqkrlehlqmtvsqykereevkqklqvysakklwvetqageakaaemk 250  fruit fly
CAG83578   229 nmrshydslvnqqehsagdehrlqlatnaladldrrrndltdkiaqleerekqeemvkklekvavyskgiflkqeterik 308  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   239 kereeakrnlsalrhsqapmvrkikeldeqlqpiedqvkaktaaikdvtlkckqtqdqldrkqkeiedinqafrlkqtee 318  Tetraodon nigrov...
CAE59031   256 iadnalveyrkveakikasadeiekleerinkearaiagtgnsareilanfqsksdkhmaenmladakskldrvkkeaei 335  Caenorhabditis b...
AAK31464   256 nmdgamieyreveksiaecekhrknledrikkdrsqisqmqrscneilakvqekgdkklmedmmqrakaklesakkaadq 335  nematode
T15650     256 nmdgamieyreveksiaecekhrknledrikkdrsqisqmqrscneilakvqekgdkklmedmmqrakaklesakkaadq 335  nematode
CAD59407   245 kdlklakkcteekeqqynqfkqemeailarkkeletskakqvaigqrstdeinsleekterledtiskqkrelmdalaka 324  African malaria ...
EAA00424   245 kdlklakkcteekeqqynqfkqemeailarkkeletskakqvaigqrstdeinsleekterledtiskqkrelmdalaka 324  Anopheles gambia...
CAD29584   251 vetqageakaaemktqvknaktqsdklknqhdkllqsqeqiekekeslrkallekqnikksrrtatecdnlnqlvenkiy 330  fruit fly
AAQ22436   251 tqvknaktqsdklknqhdkllpsqeqiekekeslrkallektrllenavaekaaidgkmdslkqgiyqkkyeleqnikks 330  fruit fly
NP_730660  251 tqvknaktqsdklknqhdkllqsqeqiekekeslrkallekqnikksrrtatecdnlnqlvenkiyeletlnksrplivs 330  fruit fly
CAG83578   309 aevaqlnaaskdlaeeretlskkmssyqqviktsendmsqkeekakqywrkyrelrnkdkeiagkmakhegdfeaaqrrl 388  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   319 adhqkrivntrrliadlkaelakvqdqpdvvprinevnvelrrnqverakmeeersdlrrekdntfaqgrslekklsdmn 398  Tetraodon nigrov...
CAE59031   336 hirevekrrnaievaetkwkaalddlngydefmiendrseseftaierelnkeeekihhkkyelsslerrragegkaskd 415  Caenorhabditis b...
AAK31464   336 hekdvekarkmidqararlqeavdtlngyeefqsemksleqkystaerdsrqeedaiqkksyemrqlenkkrdeeqnsql 415  nematode
T15650     336 hekdvekarkmidqararlqeavdtlngyeefqsemksleqkystaerdsrqeedaiqkksyemrqlenkkrdeeqnsql 415  nematode
CAD59407   325 derkteldeakvmlaafvqdcadsatalgsedqvrqeisvldgkeakiradndllmgrrqelnqkidtelkpemmsiers 404  African malaria ...
EAA00424   325 derkteldeakvmlaafvqdcadsatalgsedqvrqeisvldgkeakiradndllmgrrqelnqkidtelkpemmsiers 404  Anopheles gambia...
CAD29584   331 eletlnksrplivselerakescaaargkameqysrrrqleqklndemipeitayklkierlrnvkmqkidvssyeirak 410  fruit fly
AAQ22436   331 rrtatecdnlnqlvenkiyeletlnksrplivselerakescaaargkameqysrrrqleqklndemipeitayklkier 410  fruit fly
NP_730660  331 elerakescaaargkameqysrrrqleqklndemipeitayklkierlrnvkmqkideiraknpnlvvamnwlaqnkqry 410  fruit fly
CAG83578   389 dkheegtkvlqdkvqedqskytamcrelddpafqekkedlkaklaefdkdysetkqvvrdleakgrnesdkadqvhsale 468  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   399 nlmnvkeeklrgrhrdthaalqwlrqnrnrfngnvyepmllvinvkdhrfakyvenhipfqdlrafvfqrkddmetfmse 478  Tetraodon nigrov...
CAE59031   416 nrnerwnmldqlssdageawdwykknqskfkgeiytpfmnmilkspeaakilensigmrdrsmfvcqykedellingkqp 495  Caenorhabditis b...
AAK31464   416 nrqdryrvlqnfssdaskayrwyqqnrsqfkgdvympimdmvlktpeaakalensvgvrdrtmfvccykedellingkqh 495  nematode
T15650     416 nrqdryrvlqnfssdaskayrwyqqnrsqfkgdvympimdmcgksqnlpssaysanlffqylpstansanlpsssnsans 495  nematode
CAD59407   405 ietienvasnklrilqtrfegtykavlwlrehkhlfqgkiyepmilelnvpalenvqflentigvrdliaftcestqdmn 484  African malaria ...
EAA00424   405 ietienvasnklrilqtrfegtykavlwlrehkhlfqgkiyepmilelnvpalenvqflentigvrdliaftcestqdmn 484  Anopheles gambia...
CAD29584   411 npnlvvamnwlaqnkqryklnvydpmileltvqnhedakflenvvaqrdlfafacedkgdmsdlinelcvkqklgvnviy 490  fruit fly
AAQ22436   411 lrnvkmqkideiraknpnlvvamnwlaqnkqryklnvydpmileltvqnhedakflenvvaqrdlfafacedkgdmsdli 490  fruit fly
NP_730660  411 klnvydpmileltvqnhedakflenvvaqrdlfafacedkgdmsdlinelcvkqklgvnviycapsdrlvyspktpiddl 490  fruit fly
CAG83578   469 serrvnnrfvpvqrinmnliqkvkqiappdqfrytlpaintvrlkqnnvddqrmvnavvrataqhfvardsssaaqimrv 548  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   479 vrdkmnlkvnsisapekscskeeasrniehlrrfgffmylremfdapdevmsy--------------------------- 531  Tetraodon nigrov...
CAE59031   496 wrinttvvtaenvyedelneevrpdlkdlgfkylasncfeapaplkqylcnvaglnkipv-------------------- 555  Caenorhabditis b...
AAK31464   496 swrintsvvpaekiysedidaqlpselsrlgfkylvsncfdapaplkqflcnvsglnripf------------------- 556  nematode
T15650     496 ailpcltnsekfdifnvfwstktteflthiwflnkfrvmvlktpeaakalensvgvrdrtmfvccykedellingkqhsw 575  nematode
CAD59407   485 lflrktreelridgvnaiqsdpadklhytarhpigslkrfgfhtylidmvqgpy-------------------------- 538  African malaria ...
EAA00424   485 lflrktreelridgvnaiqsdpadklhytarhpigslkrfgfhtylidmvqgpy-------------------------- 538  Anopheles gambia...
CAD29584   491 capsdrlvyspktpiddlrcsfgfrsylvdlvtgpiplinklcasysih------------------------------- 539  fruit fly
AAQ22436   491 nelcvkqklgvnviycapsdrlvyspktpiddlrsfgfrsylvdlvtgpip----------------------------- 541  fruit fly
NP_730660  491 rsfgfrsylvdlvtgpiplinklcasysih-------------------------------------------------- 520  fruit fly
CAG83578   549 edritvreiskpfeeasrnvpvdrvrlrgygfdgyildliegpdhnlahlceaakiha---------------------- 606  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   532 -------------------------------------------------------------------lchqykvhdvpvg 544  Tetraodon nigrov...
CAE59031   556 ------------------------------------------------------------gsldlrqmdninkelerlrv 575  Caenorhabditis b...
AAK31464   557 -----------------------------------------------------------ggsdvekkiaevsqaieqtry 577  nematode
T15650     576 rintsvvpaekiysedidaqlpselsrlgfkylvsncfdapaplkqflcnvsglnripfggsdvekkiaevsqaieqtry 655  nematode
CAD59407   539 ------------------------------------------------------------------pvlnglcklyglhn 552  African malaria ...
EAA00424   539 ------------------------------------------------------------------pvlnglcklyglhn 552  Anopheles gambia...
CAD29584   540 ----------------------------------------------------------------------nipigteavg 549  fruit fly
AAQ22436   542 --------------------------------------------------------------------linklcasysih 553  fruit fly
NP_730660      --------------------------------------------------------------------------------      fruit fly
CAG83578   607 -------------------------------------------------------------vpysrqgltpeqisklpps 625  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   545 teqtkamitqvcsssflmpafrfqgritrlmnvssssqvieelnlrgavhhgrkvhaeeacekrlreiderlkalqketa 624  Tetraodon nigrov...
CAE59031   576 svymannmrfqlqrskyanrtlnsqsemrdatfwgqacflksmdvkkekddkaeeyerlkneiecmkeelkekryditkk 655  Caenorhabditis b...
AAK31464   578 svfltanircqnsksryanntlqsqsatreantwrdqffkvspvakrtdnsileeiqklkaeidirseqlrekrgaiqke 657  nematode
T15650     656 svfltanircqnsksryanntlqsqsatreantwrdqffkvspvakrtdnsileeiqklkaeidirseqlrekrgaiqke 735  nematode
CAD59407   553 ipvggadsakyvsalpdeiglfftpshrfqvsksrytgekstrsdalrtlnllnrstdhallaqkrqehqrlvrecdkir 632  African malaria ...
EAA00424   553 ipvggadsakyvsalpdeiglfftpshrfqvsksrytgekstrsdalrtlnllnrstdhallaqkrqehqrlvrecdkir 632  Anopheles gambia...
CAD29584   550 nytssipkairvyfgililnsvlcilgskkfvvtasryrsdtiltessiraknqlitvdsqqlalvmkqcseavkesdsi 629  fruit fly
AAQ22436   554 nipigteavgnytssipkairvyfggskkfvvtasryrsdtiltessiraknqlitvdsqqlalvmkqcseavkesdsik 633  fruit fly
NP_730660  521 ---------nipigteavgnytssipkairvyfggskkfvvtasryrsdtiltessiraknqlitvdsqqlalvmkqcse 591  fruit fly
CAG83578   626 lnrfisknmlytikqsrygqrytstksepidtyppkkdsqiiyekvpdrsqeqelqeqydelvqrlrplkeevkiaksll 705  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   625 aldrrdnellaekkhlselkgkrrqleqkistkqdslrqmeqnitdlkkieeetkgkvsevnsqkvamvkvfidsiklka 704  Tetraodon nigrov...
CAE59031   656 rdalqkvrmewrskksveskwenflkqekmklrnleretfdiqkaeddfanvedhvlkkvqkamaesvadhkacsekfke 735  Caenorhabditis b...
AAK31464   658 rdvlrqeqmqwkskkqvhtkwktelasemaklealenevvdisaieeeyanvekkailetkkmlensirwhkeiidkhrl 737  nematode
T15650     736 rdvlrqeqmqwkskkqvhtkwktelasemaklealenevvdisaieeeyanvekkailetkkmlensirwhkeiidkhrl 815  nematode
CAD59407   633 nqrgqiensikelqercaelreqkrdlqeqlskyqqtkmkvkrqeqkckeltarlvnvdeekvkferscrtiieqlldqq 712  African malaria ...
EAA00424   633 nqrgqiensikelqercaelreqkrdlqeqlskyqqtkmkvkrqeqkckeltarlvnvdeekvkferscrtiieqlldqq 712  Anopheles gambia...
CAD29584   630 knaitqtdneferlqavakdeqekrrkldqkiahfnslkteietlqkklealrnsdsldcletnfcnslhkdlkkifdad 709  fruit fly
AAQ22436   634 naitqtdneferlqavakdeqekrrkldqkiahfnslkteietlqkklealrnsdsldcletnfcnslhkdlkkifdada 713  fruit fly
NP_730660  592 avkesdsiknaitqtdneferlqavakdeqekrrkldqkiahfnslkteietlqkklealrnsdsldcletnfcnslhkd 671  fruit fly
CAG83578   706 qdkahlktetvdklrqyrtregkkdilaknlhtakvklkehvenppagieevkaliekkrnetrdeiaanmldrvkvikk 785  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   705 kltmekvylalkmveltaektklendfregasllrsmdqkcsqleqrraqlteqckghmkramsicrmqskdslpedlrn 784  Tetraodon nigrov...
CAE59031   736 karhnfietlckiksiklnskaedyrseredlrhvkeaaedqlktafnrrkaaknalkqecalehldvskmdptdkelye 815  Caenorhabditis b...
AAK31464   738 igifelsesicksrvnksnseaethrskledlksvkdaaedllktalnhkkaaasalmkecslktldeskmspaenkiys 817  nematode
T15650     816 igifelsesicksrvnksnseaethrskledlksvkdaaedllktalnhkkaaasalmkecslktldeskmspaenkiys 895  nematode
CAD59407   713 rrkvaaleryaaasrehdlleqrirlfeernndreanfrlledayqsakktlanvekklaevkakssdknstaralcank 792  African malaria ...
EAA00424   713 rrkvaaleryaaasrehdlleqrirlfeernndreanfrlledayqsakktlanvekklaevkakssdknstaralcank 792  Anopheles gambia...
CAD29584   710 aelcsclkaidrliieknmaqtkvsiymlqhetqiealkeseeqskaatrdfqqllqclenqisdvnkrksaiqglchge 789  fruit fly
AAQ22436   714 elcsclkaidrliieknmaqtkvsiymlqhetqiealkeseeqskaatrdfqqllqclenqisdvnkrksaiqglchgei 793  fruit fly
NP_730660  672 lkkifdadaelcsclkaidrliieknmaqtkvsiymlqhetqiealkeseeqskaatrdfqqllqclenqisdvnkrksa 751  fruit fly
CAG83578   786 lgqlipdaqkdaialaranvlvaslrsryaeveaeraqfkekfqrlkdrykaakaeyeafmankeevepeyvlffeelka 865  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   785 vrlcffgggkqafaklpdtpdeiesrlseersraecftslsenvrmrwfrrdqeikqlekeleekenaleayrkniaeak 864  Tetraodon nigrov...
CAE59031   816 kmtklfkdsnvptdkdeldqcitsektrlalvqnsgedgsiehehqlqrinkeleeectkydkliknretahqelgdlis 895  Caenorhabditis b...
AAK31464   818 slvkmfeeadvptdmntldqaitsektrlklaedsgedgsivheqrlkvldddlvlektrqeklienrarihdklgdein 897  nematode
T15650     896 slvkmfeeadvptdmntldqaitsektrlklaedsgedgsivheqrlkvldddlvlektrqeklienrarihdklgdein 975  nematode
CAD59407   793 tpdkpdfpyrkeftelpdtielvdahleelrvrfeclpqanesvadeyaqkkrqleqlragvacseqtvatleqqmaelh 872  African malaria ...
EAA00424   793 tpdkpdfpyrkeftelpdtielvdahleelrvrfeclpqanesvadeyaqkkrqleqlragvacseqtvatleqqmaelh 872  Anopheles gambia...
CAD29584   790 iptsskfpfkkefrelenidlpelreaihdfqarlecmksvnseaissyqglqnevkqleegiqesvnqaksiesgmsnl 869  fruit fly
AAQ22436   794 ptsskfpfkkefrelenidlpelreaihdfqarlecmksvnseaissyqglqnevkqleegiqesvnqaksiesgmsnly 873  fruit fly
NP_730660  752 iqglchgeiptsskfpfkkefrelenidlpelreaihdfqarlecmksvnseaissyqglqnevkqleegiqesvnqaks 831  fruit fly
CAG83578   866 qydgpdlqahvdaqidvlrqeltfanvdmdarnkyeevirqaqrtkqevvyltnkrdnaaeemqkiidvfvpelerivni 945  Yarrowia lipolyt...

Feature 1                                                                                      
CAG07476   865 erwlnplkllveqinekftaffrsmncagevdlhseneedydkygirirVKFHSNTHLHELTPYHQSGGERSVSTMLYLM 944  Tetraodon nigrov...
CAE59031   896 kwreeveemiekinlnyikffevlgcrgevsletpencldiekygimimVCFRKGENMKRLDNRVQSGGERSVATMLYLL 975  Caenorhabditis b...
AAK31464   898 nwrkevetmieqinvnyvqffdslgcrgevslevpenpldiekygimimVCFRKGESMKRLDNKVQSGGERSVATMLYLL 977  nematode
T15650     976 nwrkevetmieqinvnyvqffdslgcrgevslevpenpldiekygimimVCFRKGESMKRLDNKVQSGGERSVATMLYLL 1055 nematode
CAD59407   873 drwypeiqsvvqcingkfshfmssmgfagevelirqgerdydeygiriyVKYRNEEKLSALDRKLQSGGERAVAIAIYTL 952  African malaria ...
EAA00424   873 drwypeiqsvvqcingkfshfmssmgfagevelirqgerdydeygiriyVKYRNEEKLSALDRKLQSGGERAVAIAIYTL 952  Anopheles gambia...
CAD29584   870 ydkwepklnslvetistkfsefmesieyvgevvlsktdkdfdsygiqimVQFRRGLQLQPLDKFIQSGGERAVSIAIYSL 949  fruit fly
AAQ22436   874 dkwepklnslvetistkfsefmesieyvgevvlsktdkydfdsygiqimVQFRRGLQLQPLDKFIQSGGERAVSIAIYSL 953  fruit fly
NP_730660  832 iesgmsnlydkwepklnslvetistkfsefmesieyvgevvlsktdkimVQFRRGLQLQPLDKFIQSGGERAVSIAIYSL 911  fruit fly
CAG83578   946 vssrfaellkkkekasglvvlrtakekanpndpgpeeplpfsqwgieimVSFREGGNKCKLDGTTQSGGERSISIGTYLL 1025 Yarrowia lipolyt...

Feature 1                   ##                                     #                       
CAG07476   945 SLQELNRCPFRVVDEINQGMDPTNERRVFDIVVRTacke----ttsQYFFITPKLLQNLNYAeEMTVLCVHNGAYM 1016 Tetraodon nigroviridis
CAE59031   976 ALQQLCPVPFRCIDEINQGMDPTNERKVFDIMVGLwngtsgtltktQYFLLSPKLLHGLDMRdNVNVVMVNSTLTA 1051 Caenorhabditis briggsae
AAK31464   978 ALQQLCPVPFRCIDEINQGMDPTNERKVFDIMVGMwngttgtlsktQYFLLSPKLLHGLDMReNVNIVMVNSTLTN 1053 nematode
T15650    1056 ALQQLCPVPFRCIDEINQGMDPTNERKVFDIMVGMwngttgtlsktQYFLLSPKLLHGLDMReNVNIVMVNSTLTN 1131 nematode
CAD59407   953 SLQHMTQVPFRCVDEINQGMDPTNERKVFNMLVEEtcrt----gqsQYFFVTPKLLPRLKCNaKMNVIVVHNGKYI 1024 African malaria mosq...
EAA00424   953 SLQHMTQVPFRCVDEINQGMDPTNERKVFNMLVEEtcrt----gqsQYFFVTPKLLPRLKCNaKMNVIVVHNGKYI 1024 Anopheles gambiae st...
CAD29584   950 SLQHVTHVPFRCVDEINQGMDATNERHIFDLLLKEatkh----gsaQYLFVTPKLLRDLNYNeHLCVSIVHNSKTV 1021 fruit fly
AAQ22436   954 SLQHVTHVPFRCVDEINQGMDATNERHIFDLLLKEatkh----gsaQYLFVTPKLLRDLNYNeHLCVSIVHNSKTV 1025 fruit fly
NP_730660  912 SLQHVTHVPFRCVDEINQGMDATNERHIFDLLLKEatkh----gsaQYLFVTPKLLRDLNYNeHLCVSIVHNSKTV 983  fruit fly
CAG83578  1026 ALQGVAPVAFRALDEINQALDAKNEVIMNQHVADTaad-----fdqQLFLLSPKLIHFNYPKkMRILTICNGSGVA 1096 Yarrowia lipolytica ...

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