Conserved Protein Domain Family
ABC_SMC3_euk
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cd03272: ABC_SMC3_euk 
ATP-binding cassette domain of eukaryotic SMC3 proteins
The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Links
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Statistics
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PSSM-Id: 213239
Aligned: 44 rows
Threshold Bit Score: 215.587
Created: 21-Mar-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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  next features
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                      ## ###                                          
NP_776720    3 IKQVIIQGFRSYRDQTIVDPFSSkHNVIVGRNGSGKSNFFYAIQFVLSDEFsh-lRPEqRLALLHEGTGprvisAFVEII 81   cow
EAK90624    33 IKELKICGFKTYRDETTISFHPG-CNCIVGLNGSGKSNILAAIQFLLSDSFgn-tLVE-RRALLHEGLGpqateAYVELS 109  Cryptosporidium ...
CAD43403     3 IKQVIIEGFKSYKEQVATEEFSNkVNCVVGANGSGKSNFFHAIRFVLSDIYqn-lRSEdRHALLHEGAGhqvvsAFVEIV 81   thale cress
XP_464029    3 IKKVVVEGFKSYREEISTEPFSPkVNVVVGANGSGKSNFFHAIRFVLSDMFqn-lRSEdRGALLHEGADisvlsAFVEIV 81   Japanese rice
AAM15423    15 VYLVIIEGFKSYKEQVATEEFSNkVNCVVGANGSGKSNFFHAIRFVLSDIYqn-lRSEdRHALLHEGAGhqvvsAFVEIV 93   thale cress
NP_180285    3 FVKVIIEGFKSYKEQVATEEFSNkVNCVVGANGSGKSNFFHAIRFVLSDIYqn-lRSEdRHALLHEGAGhqvvsAFVEIV 81   thale cress
CAD59411     3 IKQVVIEGFKSYREEISTEPFSPkVNVVVGANGSGKSNFFHAIRFVLSDMFqn-lRSEdRGALLHEGAGhsvvsAFVEIV 81   rice
XP_464028    3 IKKVVIEGFKSYREEISTEPFSPkVNVVVGANGSGKSNFFHAIRFVLSDMFqn-lRSEdRGALLHEGAGhsvvsAFVEIV 81   Japanese rice
EAL49829     4 IKRISLKGFKSYQEQLNFDEFDPhYNVVIGRNGSGKSNFYDAIQFVLCDEKfgnlRAGdRQFLLYEGNGesvvsAFVEVV 83   Entamoeba histol...
CAC12695     3 IKNILISGFRSYREQAFEQELSPkNNVIVGKNGAGKSNFFAAIQFVLCEKFmn-lSSVeRKDLFHVGSGrpalpIFVEII 81   Trypanosoma brucei

Feature 1                                                                     #                
NP_776720   82 FDNSDNRLpidk----eevsLRRVIGAKKDQYFLDKKMVTKNDVMNLLESAGFSRSNPYYIVKQGKINQMATApdsqrlk 157  cow
EAK90624   110 LDNIGRRLsmyded-vvtikRIFRSSSQKNEWQVMGKNISKKDFDSILESCGISRNNPYFIVRQGKVAELATMsdasrlr 188  Cryptosporidium ...
CAD43403    82 FDNSDNRFpvdk----eeirLRRTVGLKKDDYFLDGKHITKGEVMNLLESAGFSRANPYYVVQQGKIASLTLMkdierld 157  thale cress
XP_464029   82 FDNSDNRIpvek----kvvrLRRTVASKKDEYYLDGKHISKTEVMNLLENAGFSRSNPYYVVQQGKIAALTLMkdserle 157  Japanese rice
AAM15423    94 FDNSDNRFpvdk----eeirLRRTVGLKKDDYFLDGKHITKGEVMNLLESAGFSRANPYYVVQQGKIASLTLMkdierld 169  thale cress
NP_180285   82 FDNSDNRFpvdk----eeirLRRTVGLKKDDYFLDGKHITKGEVMNLLESAGFSRANPYYVVQQGKIASLTLMkdierld 157  thale cress
CAD59411    82 FDNSDNRIpvdk----eevrLRRTVASKKDEYYLDGKHVSKTEVMNLLESAGFSRSNPYYVVQQGKIASLTLMkdserld 157  rice
XP_464028   82 FDNSDNRIpvdkeevrlrrtVASKKDEYYLDGKHVSMLFSKTEVMNLLESAGFSRSNPYYVVQQGKIASLTLMkdserld 161  Japanese rice
EAL49829    84 FDNRDRRFmier----devsVKRCIGLQKDEYFLNDKRSKKEEVMNLLESAGFSRSNPYYIVQQNRVNSLAMMkdserld 159  Entamoeba histol...
CAC12695    82 FDNSDGRLvipgksavnevrIRRTLGLKQDEFRVNDKRFTATDIRQLLESAGFSSTNPYYIVEQGQISSLANMsdeerfq 161  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  158 llrevagtrvyderkeesislmketegkrekinellkyieerlhtleeekeelaqyqkwdkmrraleytiynqelnetra 237  cow
EAK90624   189 llkeiagtrtyderrdesirllletetrkikvdsvfddiqkrievlkdeqkefkaflnldrrrrnlefllneyeweeask 268  Cryptosporidium ...
CAD43403   158 llkeiggtrvyeerrreslrimqetgnkrkqiievvhylderlreldeekeelrkyqqldkqrksleytiydkelhdare 237  thale cress
XP_464029  158 llkeigegtsckwtlihdllaankrkqidqvvhyleerlreldeekeemkkyqqldkqrrsleytildhelndtrnelal 237  Japanese rice
AAM15423   170 llkeiggtrvyeerrreslrimqetgnkrkqiievvhylderlreldeekeelrkyqqldkqrksleytiydkelhdare 249  thale cress
NP_180285  158 llkeiggtrvyeerrreslrimqetgnkrkqiievvhylderlreldeekeelrkyqqldkqrksleytiydkelhdare 237  thale cress
CAD59411   158 llkeiggtrvyedrrreslkimqetgnkrkqidqvvhyleerlreldeekeelkkyqqldkqrrsleytildhelnearn 237  rice
XP_464028  162 llkeiggetscewtfihalltankrkqidqvvhyleerlreldeekeelkkyqqldkqrrsleytildhelnearnelas 241  Japanese rice
EAL49829   160 llreiagtrvyderreesfkivmnyikerltelqeeqeelnryeeldkkrrgieysitqtkieeiekeleantkerrees 239  Entamoeba histol...
CAC12695   162 likdvagtrvyevrrkesekileetevqhekigesiaqleerleelrsesdelmsfqeidkkrkcvqycilnsdlnaare 241  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  238 kldelsakretsgeksrqlrdaqqdardkmedierqvrelktkisamkeekeqlsaerqeqikqrtklelkakdlqdela 317  cow
EAK90624   269 geqeyfeklsksrerlssvernlnlisssiqsliesqknldiqleelehkkkeiqnkishysasindlnleqdtheshqr 348  Cryptosporidium ...
CAD43403   238 kleqvevartkaseestkmydrvekaqddsksldeslkeltkelqtlykeketveaqqtkalkkktkleldvkdfqdrit 317  thale cress
XP_464029  238 mddnrrkisermshadnevvdvrekirsfekeikfstkginenkaqkedvekkctevlkvvaqieldlrdikdrilnekl 317  Japanese rice
AAM15423   250 kleqvevartkaseestkmydrvekaqddsksldeslkeltkelqtlykeketveaqqtkalkkktkleldvkdfqdrit 329  thale cress
NP_180285  238 kleqvevartkaseestkmydrvekaqddsksldeslkeltkelqtlykeketveaqqtkalkkktkleldvkdfqdrit 317  thale cress
CAD59411   238 elasvddnrrkisermshadnevvdvrekvktfdkeikystkgindtkaqkegvekkrtealkvvaqieldlrdikdril 317  rice
XP_464028  242 mddnrrkisermshadnevvdvrekvktfdkeikystkgindtkaqkegvekkrtealkvvaqieldlrdikdrilnekr 321  Japanese rice
EAL49829   240 himeedkeeeikevkrrrrilkeevntleqkrvivsnqaqeaerlkvegeirqegrqeikemkeemekaknrseeikeei 319  Entamoeba histol...
CAC12695   242 elrrlddernsymsrsgrnhydideakaiiseaeseirncdqrilrlegelqdldtkrgtlmrekeivqlncmsslntmk 321  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  318 gnseqrkrllkerqkllekieekqkelaetepkfnsvkekeergiarlaqatqertdlyakqgrgsqftskeerdkwikk 397  cow
EAK90624   349 ilylsnlenetkskilaietsikdekelmykykikynsilkekdmlsqqesslisknnemefstisekrsvinrkielhn 428  Cryptosporidium ...
CAD43403   318 gniqskndaleqlntveremqdslreleaikplyesqvdkenqtskrinelektlsilyqkqgratqfsnkaardkwlrk 397  thale cress
XP_464029  318 akdeaardsqsvrmeserskselaetskvhqtklreeeeisksimdrqkqlsilyqkqgratqfankaardkwlqkeidd 397  Japanese rice
AAM15423   330 gniqskndaleqlntveremqdslreleaikplyesqvdkenqtskrinelektlsilyqkqgratqfsnkaardkwlrk 409  thale cress
NP_180285  318 gniqskndaleqlntveremqdslreleaikplyesqvdkenqtskrinelektlsilyqkqgratqfsnkaardkwlrk 397  thale cress
CAD59411   318 nekrakdeaakdlqsvrmesekskselaeiskvhqaklkeeeeisksimdrekrlsilyqkqgratqfankaardkwlqk 397  rice
XP_464028  322 akdeaakdlqsvrmesekskselaeiskvhqaklkeeeeisksimdrekrlsilyqkqgratqfankaardkwlqkeidd 401  Japanese rice
EAL49829   320 nkmnqeekeindkllerrrqeaeaqasvdefynkigrkakyssdeeykeaieeeikevemfvekkekekkelqkeveemk 399  Entamoeba histol...
CAC12695   322 rtesvktnvlkrvgelnkqiaetnaglkkklaiiqqeqltvdqkseelsaiegklkalearrarqllfknkqerdnwlae 401  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  398 elksldqaindkkrqiaaihkdledteankeknleqynkldqdlnevkarveeldrkyyevknkkdelqsernylwreen 477  cow
EAK90624   429 iekeklsshlcsikkslaekqdelrvldsnilkwkedqfksqknldsiiekirvnieeqqmalekkheinkslyekenqq 508  Cryptosporidium ...
CAD43403   398 eiedlkrvldsntvqeqklqdeilrlntdlterdehikkheveigelesriskshelfntkkrerdeeqrkrkekwgees 477  thale cress
XP_464029  398 lecvllsnrkqggllqeeiqklkdkinnlnsyfefyesesnklesalakkhsdyndlrkqrdklqeernyeanvtaekdr 477  Japanese rice
AAM15423   410 eiedlkrvldsntvqeqklqdeilrlntdlterdehikkheveigelesriskshelfntkkrerdeeqrkrkekwgees 489  thale cress
NP_180285  398 eiedlkrvldsntvqeqklqdeilrlntdlterdehikkheveigelesriskshelfntkkrerdeeqrkrkekwgees 477  thale cress
CAD59411   398 eiddlervllsnrkqegllqeeiqklkdeinnlnsyiesrksessklesalakkhndyndlrkqrdelqeerksfwkeea 477  rice
XP_464028  402 lervllsnrkqegllqeeiqklkdeinnlnsyiesrksessklesalakkhndyndlrkqrdelqeerksfwkeeadvta 481  Japanese rice
EAL49829   400 kingsqintqeihevfigkikmeelrkrkeevgikkrtndtkminfentrqrlmkeviklykraegtrikkqltiaeylk 479  Entamoeba histol...
CAC12695   402 esnrnrknienykhelkftcseiqkvekqiqdeeteqknweesltksdsvitelkskyeetmafrnslsvkkgdlwreqs 481  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  478 aeqqalaakredlekkqqllraatgkailngidsinkvldhfrrkginqhvqngyhgivmnnfecepafytcvevtagnr 557  cow
EAK90624   509 siissrilelenyigsrakhsvkmglnlareyceknnlswggldndeginetlvfgtvlevisvddiyttavevaagnni 588  Cryptosporidium ...
CAD43403   478 qlsseidklktelerakknldhatpgdvrrglnsirricadyringvfgplvelvdcdekfftavevtagnslfnvvven 557  thale cress
XP_464029  478 lkenlvnakeklgnatpgdiirglncvsritmehgitgvvgpilelidcdeklftavevtagnslfhvvvenddistkii 557  Japanese rice
AAM15423   490 qlsseidklktelerakknldhatpgdvrrglnsirricadyringvfgplvelvdcdekfftavevtagnslfnvvven 569  thale cress
NP_180285  478 qlsseidklktelerakknldhatpgdvrrglnsirricadyringvfgplvelvdcdekfftavevtagnslfnvvven 557  thale cress
CAD59411   478 dvtaeidrlkddlvkaqksldhatpgdirrglnsvsriirdhgitgvfgpvlelvdceekfftavevtagnslfhvvven 557  rice
XP_464028  482 eidrlkddlvkaqksldhatpgdirrglnsvsriirdhgitgvfgpvlelvdceekfftavevtagnslfhvvvenddis 561  Japanese rice
EAL49829   480 ryveekginrpkikyygtvvenieseerlytaleacsgngllyciveddetatklievleekkigrmsfiplnqikgkeq 559  Entamoeba histol...
CAC12695   482 alvqtvrtlrenhnkarsqlekvirsdvrqglqslkevldeladpsltnavhgqlieligvsngyetavevtagnslfnv 561  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  558 lfyhivdsdevstkilmefnkmnlpgevtflplnkldvrdtaypetndaipmisklrynprfdkafkhvfg--------- 628  cow
EAK90624   589 hnlivkdkeiatkivshikafnghrndikyrtnysivlspiddikqlnkshskydigseknaismidiiqfdekvrpvie 668  Cryptosporidium ...
CAD43403   558 ddistkiirhlnslkggrvtflplnrikaprvnypkdsdaipllkklkfdskfepalgqvfgr----------------- 620  thale cress
XP_464029  558 qvltrekggrvtfiplnrvkvpdvsyprsddfvpllerlecnkanhrrafeqvfgrtvickdletatkvar--------- 628  Japanese rice
AAM15423   570 ddistkiirhlnslkggrvtflplnrikaprvnypkdsdaip-------------------------------------- 611  thale cress
NP_180285  558 ddistkiirhlnslkggrvtflplnrikaprvnypkdsdaipllkklkfdskfepalgqvfgrt---------------- 621  thale cress
CAD59411   558 ddistriiqvltrekggrvtfiplnrvkvpdvscpqspdfvpllkklkyradhrrafeqvfg------------------ 619  rice
XP_464028  562 triiqvltrekggrvtfiplnrvkvpdvscpqspdfvpllkklkyradhrrafeqvfgrt-------------------- 621  Japanese rice
EAL49829   560 egeetekvksliknikykeevrkaiefvfgntmickkgeda--------------------------------------- 600  Entamoeba histol...
CAC12695   562 vvdsfevsaillenmnsrkkpgrisffpmdtcrgtvtrfgegvecssladhiicd------------------------- 616  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  629 -------------------------------------ktlicrsmevstqlaraftmdcitlegdqvshrgaltggyydt 671  cow
EAK90624   669 qifgnyvivesldnakhlvdkynvncitldgdewdnkgcvrggyrninlpgaqqnsiiicsrqlknlihensilrseiyn 748  Cryptosporidium ...
CAD43403   621 ---------------------------------------------tvvcrdlnvatrvaknddldcitmegdqvsrkggm 655  thale cress
XP_464029  629 ------------------------------------dnglncitldgsfklfhlslaalingvilirvvircsklkfvkt 672  Japanese rice
AAM15423   612 ------------------------------------------------------------------llkklkfdskfepa 625  thale cress
NP_180285  622 --------------------------------------------vvcrdlnvatrvaknddldcitmegdqvsrkggmtg 657  thale cress
CAD59411   620 ---------------------------------------------rtvicrdletatkvargngldcitldgdqvarkgg 654  rice
XP_464028  622 -----------------------------------------------vicrdletatkvargngldcitldgdqvarkgg 654  Japanese rice
EAL49829   601 -------------------------------------------------------------------ikyqkeyqvkcvs 613  Entamoeba histol...
CAC12695   617 -----------------------------------------------------pkfagivaelfgntavvtsiadgenvs 643  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  672 rksrlelqkdvrkaeeelgeleaklnenlrrnierinneidqlmnqmqqietqqrkfkasrdsilsemkmlkekrqqsek 751  cow
EAK90624   749 ikskikeiedrvfelshdreeylstrerfisqiskskemihlseskkrniqsiiikvkeeeekavrstdtvqnyivalks 828  Cryptosporidium ...
CAD43403   656 tggfydhrrsklrfmniimqntksinekekeledvrrqhvslidqqitqlvteqqrleadwtlcklqveqlkqeianank 735  thale cress
XP_464029  673 iknnmkaieekeehlknvernlsdilspclhdadkkmtdlvtkqqqmdaesdhakselehfkvgiastmkqigslekalg 752  Japanese rice
AAM15423   626 lgqvfgrtvvcrdlnvatrvaknddldcitmegdqvsrkggmtdqqitqlvteqqrleadwtlcklqveqlkqeianank 705  thale cress
NP_180285  658 gfydhrrsklrfmniimqntksinekekeledvrrqlqdvslidqqitqlvteqqrleadwtlcklqveqlkqeianank 737  thale cress
CAD59411   655 mtggfydsrrsklkfvkiirdnktaiekkaahlenvgsklrdiidkkitdlvtkqqqmdaerdhakseleqfkvdiasam 734  rice
XP_464028  655 mtggfydsrrsklkfvkiirdnktaiekkaahlenvgsklrdildkkitdlvtkqqqmdaerdhakseleqfkvdiasam 734  Japanese rice
EAL49829   614 fdgdvfngkgivtggyrgegiieiirsieetkerikevekdiarseaekkrieeeqkeimkemeeisskiaeeevkyeke 693  Entamoeba histol...
CAC12695   644 kkyacdavtldgdqvsrrggitggyiesrslklsafkyekvaaadflrgdealkkitqeldnvnqaltgvvttlsslkte 723  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  752 tfmpkqrslqsleaslhamestreslkaelgtdllsqlsledqkrvdalndeirqlqqenrqllneriklegiitrvety 831  cow
EAK90624   829 elsceslsngltldeenllkeiiskirtleyyeipkvereisdlcndidkhevhlntlfeelyriqeekqeednmklncd 908  Cryptosporidium ...
CAD43403   736 qkhaihkaieykekllgdirtridqvrssmsmkeaemgtelvdhltpeereqlsklnpeikdlkekkfayqadrieretr 815  thale cress
XP_464029  753 kkeksldniqnqivqiqsgiamkynemgteiidqltseerdlllqlnteltelkgkfvlcrnrrieietrkeelkanlst 832  Japanese rice
AAM15423   706 qkhaihkaieykekllgdirtridqvrssmsmkeaemgtelvdhltpeereqlsklnpeikdlkekkfayqadrieretr 785  thale cress
NP_180285  738 qkhaihkaieykekllgdirtridqvrssmsmkeaemgtelvdhltpeereqlsklnpeikdlkekkfayqadrieretr 817  thale cress
CAD59411   735 kqmvsldkalgkkeksldnirnqieqiqsgiamkndemgtelidqltseerdllsrlnpeitelkekfllcknsrieiet 814  rice
XP_464028  735 kqmvsldkalgkkeksldnirnqieqiqsgiamkndemgtelidqltseerdllsrlnpeitelkekfllcknsrieiet 814  Japanese rice
EAL49829   694 rmermikikkseriresiknkekrieenekiifrntqkllilqnekdnkniidrseiekakkkleeiqnkvrelekkrve 773  Entamoeba histol...
CAC12695   724 mssitkskdgsqvveqhaqrkaaldrqkdklyaskkqledmintaqvniatyqhegkeafksawsegeqrelealvndvd 803  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  832 lnenlrkrldqveqelnelreteggtvltattseleainkrvkdtmarsedldnsidkteagikelqksmerwknmekeh 911  cow
EAK90624   909 nfetngllmeynklleeskeffneiinkvestkkksieieelkrsrmqeeslalnsrnelislvsslqkkydkfrqakei 988  Cryptosporidium ...
CAD43403   816 kaeleaniatnlkrritelqatiasidddslpssagtkeqelddaklsvneaakelksvcdsidektkqikkikdekakl 895  thale cress
XP_464029  833 nlmrrqkefeavissadsktlsleaeskeqelnssksslddltamlkanvdainnftikieelkrqrdnlktleanldqt 912  Japanese rice
AAM15423   786 kaeleaniatnlkrritelqatiasidddslpssagtkeqelddaklsvneaakelksvcdsidektkqikkikdekakl 865  thale cress
NP_180285  818 kaeleaniatnlkrritelqatiasidddslpssagtkeqelddaklsvneaakelksvcdsidektkqikkikdekakl 897  thale cress
CAD59411   815 rkeeletnlstnlmrrqkeleaiissadsktlpleaeskeqelksskrsldeltamlkanvdainnftrkieelkrqrdn 894  rice
XP_464028  815 rkeeletnlstnlmrrqkeleaiissadsktlpleaeskeqelksskrsldeltamlkanvdainnftrkmeelkrqrdd 894  Japanese rice
EAL49829   774 ienrrqvlrneyqfgiisrineierkmrevesggdesdiekykevlsksmeelqrineeiekkiqeertleeqqegieke 853  Entamoeba histol...
CAC12695   804 drrmelsklqrrsaqlaaevraledmrlnlnvhltatkkffhdsaqlsasntaitnekenldddisfnsqqanevyrlld 883  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  912 mdainhdtkelekmtnrqgmllkkkeecmkkirelgslpqeafekyqtlslkqlfrkleqcntelkkyshvnkkaldqfv 991  cow
EAK90624   989 alhertkysdsqnviseinipkekskvyqelqivqkklsedyrsinrkviseldqfiqeytdlsdrhkelnsamssiqll 1068 Cryptosporidium ...
CAD43403   896 ktleddckgtlqdldkkleelfslrntllakqdeytkkirglgplssdafdtykrknikelqkmlhrcseqlqqfshvnk 975  thale cress
XP_464029  913 vrdgakdleqlmssrsmhlakqeecmkkirdlgltplptdafetyyrqknkrqlqkmlydcneqlqqfrhvkkkpldcvn 992  Japanese rice
AAM15423   866 ktleddckgtlqdldkkleelfslrntllakqdeytkkirglgplssdafdtykrknikelqkmlhrcseqlqqfshvnk 945  thale cress
NP_180285  898 ktleddckgtlqdldkkleelfslrntllakqdeytkkirglgplssdafdtykrknikelqkmlhrcseqlqqfshvnk 977  thale cress
CAD59411   895 lkaleanleqtvqdgakdleqlmssrsmhlakqeecmkkirdlgslpadafetykrknkkqlqkmlydcneqlqqfshvn 974  rice
XP_464028  895 lkaleanleqtvqdgakdleqlmssrsmhlakqeecmkkirdlgslpadafetykrknkkqlqkmlydcneqlqqfshvn 974  Japanese rice
EAL49829   854 kekkekiqnerekkmarlfekmtvleskrkelikrreeigknyeeikgnkgeledmleetmkeikkyrhvnkkakdqykg 933  Entamoeba histol...
CAC12695   884 earkeklrreeeveklrsgylealnsiqerrdfdgrtlmqqahcikrrdgaaekirqlgvipkeaetysglsrekliqtl 963  Trypanosoma brucei

Feature 1                                                                                      
NP_776720  992 nfseqkeklikrqeeldrgyksimelmnvlelrkyeaiqltfkqvsknfsevfqklvpggkatlvmkkrrxerqsglrmk 1071 cow
EAK90624  1069 ietldiqkektllktfeeinfyfnqvfrelipngdaklilrlssdarsiadenddntnkkpsykknssinnkylnntmak 1148 Cryptosporidium ...
CAD43403   976 kaldqyvnfteqreelqnrqaeldagdekikelitvldqrkdesiertfkgvahhfrdvfselvqdgygnliimkkkdld 1055 thale cress
XP_464029  993 fteqreqlerrraeldagdqkirelvsildqrkdesiertfkgvarhfrevfselvqgghghlvmmkkkdgdagdedidn 1072 Japanese rice
AAM15423   946 kaldqyvnfteqreelqnrqaeldagdekikelitvldqrkdesiertfkgvahhfrdvfselvqdgygnliimkkkdld 1025 thale cress
NP_180285  978 kaldqyvnfteqreelqnrqaeldagdekikelitvldqrkdesiertfkgvahhfrdvfselvqdgygnliimkkkdld 1057 thale cress
CAD59411   975 kkaldqyvnfteqreqlqrrraeldagdqkirelisvldqrkdesiertfkgvarhfrevfselvqgghghlvmmrkkdg 1054 rice
XP_464028  975 kkaldqyvnfteqreqlqrrraeldagdqkirelisvldqrkdesiertfkgvarhfrevfselvqgghghlvmmrkkdg 1054 Japanese rice
EAL49829   934 fieqqeglidrkkeildtqetiysliesldekkeeaiertfkgvskgfteifnklvpqgkgtlvmlkkpyeqnqltqtps 1013 Entamoeba histol...
CAC12695   964 kecnkaaekyahinrkavdqyntlmetknglvaqkedlqnelksirdlmdhldckkdeavertykqiqlhfeqvfkelvt 1043 Trypanosoma brucei

Feature 1                                                                              ##      
NP_776720 1072 ekgvvkgergsgpqssvpsvdqftgvgirvsftgKQGEMREMQQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALD 1151 cow
EAK90624  1149 esdstllgigirvtfhvgsnsqinstntqkkpngQAGNYYSLNQLSGGQKTLVALAFLFALHRADPAPMYLLDEVDAALD 1228 Cryptosporidium ...
CAD43403  1056 nddeddddddggreavtegrvekyigvkvkvsftGQGETQLMKQLSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALD 1135 thale cress
XP_464029 1073 dedgprepdsedrmekyigvkflrevlefqvsftGQGETQSMKQLSGGQKTVVALTLIFAIQRCDPAPFYLFDEIDAALD 1152 Japanese rice
AAM15423  1026 nddeddddddggreavtegrvekyigvkvkvsftGQGETQLMKQLSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALD 1105 thale cress
NP_180285 1058 nddeddddddggreavtegrvekyigvkvkvsftGQGETQLMKQLSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALD 1137 thale cress
CAD59411  1055 daddddndedgprepdpegriekyigvkvkvsftGKGETQSMKQLSGGQKTVVALTLIFAIQRCDPAPFYLFDEIDAALD 1134 rice
XP_464028 1055 daddddndedgprepdpegriekyigvkvkvsftGKGETQSMKQLSGGQKTVVALTLIFAIQRCDPAPFYLFDEIDAALD 1134 Japanese rice
EAL49829  1014 tqtqsenkfpitsqpkkirtetysgislrvifpaFGGDAKTIQQLSGGQKTVVALSLIFAIQRCDPAPFYLFDEIDSNLD 1093 Entamoeba histol...
CAC12695  1044 tddcygklqlimsntrkeagedpyvavqikvsfgLGAAVTDLKQLSGGQKSLVTLALIFAIQRCDPAPFYLFDEIDAALD 1123 Trypanosoma brucei

Feature 1                                #                        
NP_776720 1152 AQHRKAVSDMIMELav--haQFITTTFRPELLESADkFYGVKFRNKVSHID 1200 cow
EAK90624  1229 DQYRWSVANLIKKQsi--stQFIVTTFRPQILQVADkYFQVSQVNRSSFVS 1277 Cryptosporidium parvum
CAD43403  1136 PQYRTAVGNLIRRLaddygtQFITTTFRPELVRVADkIYGVFHKNRVSIVN 1186 thale cress
XP_464029 1153 TQYRTAVGNMIRRLsdmadtQFIATTFRPEIVKVADkIYGVTYKNRVSYIN 1203 Japanese rice
AAM15423  1106 PQYRTAVGNLIRRLaddygtQFITTTFRPELVRVADkIYGVFHKNRVSIVN 1156 thale cress
NP_180285 1138 PQYRTAVGNLIRRLaddygtQFITTTFRPELVRVADkIYGVFHKNRVSIVN 1188 thale cress
CAD59411  1135 PQYRTAVGSIIRRLadmadtQFIATTFRPEIAKVADkIYGVTHKNRVSYIN 1185 rice
XP_464028 1135 PQYRTAVGNMIRRLadmadtQFIATTFRPEIAKVADkIYGVTHKNRVSYIN 1185 Japanese rice
EAL49829  1094 TVYREAVSSLIQEQsk--eaQYIVTTFRPELILPANkWYEIKHQNKVSTIL 1142 Entamoeba histolytica HM-1:IMSS
CAC12695  1124 TEYRASVAKLLSKEsg--scQFITATFKNEMLDVADhVLGVFFHNKISRIQ 1172 Trypanosoma brucei

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