Conserved Protein Domain Family
ABC_CcmA_heme_exporter

?
cd03231: ABC_CcmA_heme_exporter 
Cytochrome c biogenesis ATP-binding export protein
CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Statistics
?
PSSM-Id: 213198
Aligned: 5 rows
Threshold Bit Score: 237.006
Created: 11-Dec-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
  next features
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                        ## ###                                      #
Q8FFR2      4 LEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLLRLLTGLSRPDAGDVLWqgqplhqvrdsyhqnLLWIGH 83  Escherichia coli O6
Q98EA4      3 LIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLLLenggddf--psiasaCHYLGH 80  Mesorhizobium loti
Q9I3N7     14 LETVGLACERDWRMLFERLDLRLAAGEMLQVVGPNGSGKTSLLRLLSGLMQPTAGEVRLngrplaeqrgelarsLLWIGH 93  Pseudomonas aerugi...
Q9Z651      2 LEAKELTCARDERVLFSQLSFTVGAGNIVQIEGPNGAGKTSLLRILAGLSRPESGEILWnqtavgrqrdiwqreMLYLGH 81  Pantoea citrea
P29959      4 LAVDQLTVSRGGLAVLEGVSFSLAAGHALVLRGPNGIGKTTLLRTLAGLQPPLAGRVSMpp-----------egIAYAAH 72  Rhodobacter capsul...
Feature 1                                                                             ##      
Q8FFR2     84 QPGIKTRLTALENLhfyhrdg---dtaqcleALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAID 160 Escherichia coli O6
Q98EA4     81 QNAMKTALSVVENLrfwrdfng-rgdsgveeALDTVGLGGVGHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLD 159 Mesorhizobium loti
Q9I3N7     94 AAGIKGLLSAEENLtwlcalhqpasreaiwqALADVGLRGFEDVPCHTLSAGQQRRVALARLYLDAPPLWILDEPFTALD 173 Pseudomonas aerugi...
Q9Z651     82 LPGVKGVLSPLENLrffhpdc---sdeqifdALDEVDLTGYEDAIVAQLSAGQQRRVALARLWLSQARLWILDEPLTAID 158 Pantoea citrea
P29959     73 ADGLKATLSVRENLqfwaaih---atdtvetALARMNLNALEHRAAASLSAGQKRRLGLARLLVTGRPVWVLDEPTVSLD 149 Rhodobacter capsul...
Feature 1                              #                   
Q8FFR2    161 VNGVDRLTQRMAQHTEQGGIVILTTHQPLNVaeskirRISLT-QT 204 Escherichia coli O6
Q98EA4    160 KASEARFAGLMAGHCAGGGMIVAATHLPLGIeg---aELRMG-VA 200 Mesorhizobium loti
Q9I3N7    174 KQGVAQLETHLAGHCQRGGMVVLTTHHSLQQvpagyrELDLGaLK 218 Pseudomonas aeruginosa
Q9Z651    159 KAGVEKIMSQFASHAGRGGSVILTTHQDLPDqqdvvrKIRLT-AE 202 Pantoea citrea
P29959    150 AASVALFAEAVRAHLAAGGAALMATHIDLGLse--arVLDLApFK 192 Rhodobacter capsulatus

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap