2D2F


Conserved Protein Domain Family
ABC_FeS_Assembly
?
cd03217: ABC_FeS_Assembly 
Click on image for an interactive view with Cn3D
ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Links
?
Statistics
?
PSSM-Id: 213184
Aligned: 36 rows
Threshold Bit Score: 245.514
Created: 13-Dec-2004
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
  next features
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site
  • Structure:Mg-ADP bound; 4.0A contacts
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                         ## ###                                      
2D2F_A      4 LEIRDLWASIDGe-tILKGVNLVVPKGEVHALMGPNGAGKSTLGKILaGDPEYTverGEILLDGeNILELspdERARKGL 82  Thermus thermophil...
Q60350      7 LKVEDLHVYRGNr-eILKGVNLTVEENEIHAIIGPNGAGKSTLAYTImGISGYKptkGRIIFKGvDIIDKnitERARMGM 85  Methanocaldococcus...
NP_142809   2 LCLRNVTYRVDGr-rIIERINMRFKEGMTYSILGPNGAGKSTIAYILmGVMKPSe--GRVLLDGdDITNLsitERARLGI 78  Pyrococcus horikos...
NP_229218   4 LELIDVWYEVEGk-aILKGINARFEKQRVYSILGTNGAGKSTLAYLImGLEGYRptrGKILLDGeDITDLsvtERAKRGI 82  Thermotoga maritim...
NP_614516   4 LEVKDLRVESEDgteIVRGASLTVDEGEIVDLIGPNGSGKSTLAKTIvGCSGYEvveGEVRFKGrDITDLpmyERARMGL 83  Methanopyrus kandl...
NP_143263   2 LKIVDLHVEAGGr-eILKGVNLTVNEGEFHVIMGPNGSGKSTLALTLaGHPNYKvtkGGIFFEDkEITNLtpdERAKMGI 80  Pyrococcus horikos...
NP_071186   4 LRVVNLGVKVGEk-kILKNVNLFIKEGETFVLFGPNGSGKSTLLNALiGNPSYKvtsGRILFKKvDITNLptnERVKLGI 82  Archaeoglobus fulg...
NP_276277   3 LEITDLAVEVSGk-qVLKDIDLYIDRGETHVLLGPNGSGKSTLFMTIlGFPKYRvtnGQIIFKGeDITDLsttERVRMGI 81  Methanothermobacte...
NP_988288   2 LQIEDLSVKVGDk-eILKDIHLYIEKGESHVLFGPNGAGKSTLLNTIlGNPKYEvvrGNIYFKGkDITDMpmhERAQLGI 80  Methanococcus mari...
YP_010243   2 LEIRDLHVCIGDv-eVLKGINLHIRPGETFILFGPNGSGKTTLLMTLmGFANYKvtqGQILFKGhDITNApmyERARLGM 80  Desulfovibrio vulg...

Feature 1         #                                                                           
2D2F_A     83 FLAFQyPVEVPGVTIANFLrlalqaklgrevgvaefwtkvkkalelldwdesylsRYLNEGFSGGEKKRNEILQLLVLEP 162 Thermus thermophil...
Q60350     86 TLAWQePARFEGIKVKNYLmlgmnekykkdkeiaeek-irealklvnldpdkyldRYVDETLSGGERKRIELASIICMEP 164 Methanocaldococcus...
NP_142809  79 TLLWQePARYDGITVEKYLtlggkikvdknemre-------ilelvglpyelyahRFVDKSLSGGERKRIELASILMLRP 151 Pyrococcus horikos...
NP_229218  83 TLMWQePARFTGIKIRDYLtlggrrkvskeeler-------vlelvglnpalyleRNVDEKLSGGERKRVELASILLMKP 155 Thermotoga maritim...
NP_614516  84 TMSWQePARFEGLTVGEYLsvctddedwarrc----------lrivgldpeeywdRECGENLSGGERKRVELAAVMAMRP 153 Methanopyrus kandl...
NP_143263  81 LLAFQvPPEIQGVRIIDFLtqtlseiknldaseayn--iiiekakelwfreddlrRYINVGFSGGERKRLELLQALLLEP 158 Pyrococcus horikos...
NP_071186  83 GIAFQnPPKISGVKLIDVLrycarvggygedki--------lelaekmrmtdhlyREINMGFSGGEVKRSELLQLMLMNP 154 Archaeoglobus fulg...
NP_276277  82 GVSFQnPPAIRGVKLMDLLkvesgletedeltpel-----rglaakmkfdesfleRDVNLGFSGGEVKRSEILQLLAQKP 156 Methanothermobacte...
NP_988288  81 GISYQsPPAISGVRLETMInaiskrsdeemee-----------makrlnirhfyqRDLNVGFSGGEVKRSELLQIFAQNP 149 Methanococcus mari...
YP_010243  81 GMSFQrPPTIHGLKTGHLVrmcgrgrevdveg-----------laqrvnfdrfleRDVNAGFSGGEIKRSELLQLMAQQP 149 Desulfovibrio vulg...

Feature 1          ##                                               #                         
2D2F_A    163 TYAVLDETDSGLDIDALKVVARGVNAMrgp----------------nfgALVITHYQRILny-iqPDK-VHVMMdGRVVA 224 Thermus thermophil...
Q60350    165 DLAILDEPDSGIDIVSFDEIKRVFDYLkdk----------------gcsLLVITHREELAe---hADR-VSLICaGEVIK 224 Methanocaldococcus...
NP_142809 152 RYAILDEPDSGLDITAGELIENVLEYFrrv----------------gttVILITHHEEIAa---kTDF-AYFVCaGRIIK 211 Pyrococcus horikos...
NP_229218 156 RYTILDEPDSGIDIMSLEMIEKVLSELvsa----------------ggsVILVTHREEIAl---eSDY-AFLIChGSILK 215 Thermotoga maritim...
NP_614516 154 DLVILDEPDAGLDMSSMEDLAKVIETMree----------------gsaVLLITHNRDLAeq--vGDR-AYLMMdGKIVD 214 Methanopyrus kandl...
NP_143263 159 KLLILDEPDSGVDVDSLSVISRKIEELhkk----------------gvsIILITHYGRIFghidkEKLkVNIMRdGKIVM 222 Pyrococcus horikos...
NP_071186 155 DLVLLDEPDSGVDLENVALIGEAIRTLlerdkee---------gertksGIIITHQGHILdy-vdADY-AAILYnGRIAC 223 Archaeoglobus fulg...
NP_276277 157 DFIMFDEPDSGVDIENVELLAEEINVLldkdkkp---------glrkkaGLLITHLGYILnf-vsADT-AHVLMdGRIAC 225 Methanothermobacte...
NP_988288 150 DLVMFDEPDSGVDVENVELLGGIINHLldkdrkp---------sernksGLIITHLGYILnf-meVDK-AHVLLdGVIAC 218 Methanococcus mari...
YP_010243 150 DLVLFDEPESGVDLENMSLIGQTARQLldgiapascasikqrkaacktaGLIITHTGYILey-vnADR-GQVMYdGHLCC 227 Desulfovibrio vulg...

Feature 1                      
2D2F_A    225 TG-GPELAl-eLEAKGY 239 Thermus thermophilus HB8
Q60350    225 SG-DPKEVg-eFYKKEC 239 Methanocaldococcus jannaschii
NP_142809 212 KGfSREIVd--YYKKTC 226 Pyrococcus horikoshii OT3
NP_229218 216 EGnPSEIVq--FYKNSC 230 Thermotoga maritima MSB8
NP_614516 215 EGdPKDVVlkcLMCGGG 231 Methanopyrus kandleri AV19
NP_143263 223 RG-GSELIs-mIEEKGF 237 Pyrococcus horikoshii OT3
NP_071186 224 IGePKDILn-qIRNHGY 239 Archaeoglobus fulgidus DSM 4304
NP_276277 226 SGnPQEIIe-dIRKDGF 241 Methanothermobacter thermautotrophicus str. Delta H
NP_988288 219 SGtPDEILn-eIIKNGY 234 Methanococcus maripaludis S2
YP_010243 228 EArPRDILe-hIGKHGY 243 Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap