Conserved Protein Domain Family
GATase1_PfpI_1

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cd03169: GATase1_PfpI_1 
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.
Statistics
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PSSM-Id: 153243
View PSSM: cd03169
Aligned: 23 rows
Threshold Bit Score: 214.049
Threshold Setting Gi: 77551730
Created: 17-Nov-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
conserved cys
Feature 1:conserved cys residue [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
YP_095993    10 KILMIVGDFNEDLEVYFPYQAMLMNNYLIDTVSPgKNKGDfiqtavhdldkphlqSYTEKLGHLFp-ITADFSKItlkdY 88  Legionella pneum...
CAC11607      3 RVLILTGDAGESLEVMYPLQRMKEEGFEVDVAAPeKKKIQlvvhdf----eegfdTYTEKPGYKLq-ADLAFKDVdpskY 77  Thermoplasma aci...
NP_104378     5 KILMLVGEFSEEYEIFVFEQAMHAVGHTVHVVCPdKKAGDvlktslh--dfeghqTYTEKLGHDYi-LNKTFSEVdpakY 81  Mesorhizobium lo...
NP_558487    10 KILIIAGDAVEALEIFYPYFRLKEEGWDVDVAAPtKKDLRtvvhdf----epgweTYSEKPGYLFkwVTKTSAEVkpeeY 85  Pyrobaculum aero...
CAD76517     23 KVLIVIGDATELLDTMYPYYRLQEAGFEPVVIAPeKRLYQlvlhei----kpgwtITKEWEGYTLd-CDVPFSEVkeddY 97  Rhodopirellula b...
YP_005057     4 KVLILAGDAAEALETFYPLQRLQEEGFTVHVAAPrKKVIQtvvhdf----eplmeTYTEKLGYRLq-ADLSFTEVdpeaY 78  Thermus thermoph...
YP_147291     4 KVLIITGDAVEALEVYYPYYRLLEEGHDVTIAAPkKKKLHtvvhd-----fadwdTYVEKQGYLId-AHASFAEVdpaqY 77  Geobacillus kaus...
YP_177000     3 KMLILTGDAVEALEVFYPYYRFLEEGFEVDIASPaVKKLYtvnhdf----vegyeTFVEKPSYQLd-SHIAFENVrpdeY 77  Bacillus clausii...
ZP_00527128   3 KILVITGDGGESYETLYAVHRFQEEGWEVAVAAPsRRRLNlvmhdf----kpgwdTYIERRGYGLd-ADLSFDEVkvdeY 77  Solibacter usita...
ABA94527    210 AVLFLCADYVDDYEANVPFRALAGVGCRVEAACPtKRKGEacvtaiy--datpaaASDERRGHNFa-VTADWGDVdadrY 286 Japanese rice
Feature 1                                              #                                        
YP_095993    89 DALIIPGGRAAEYQRLNkdi--laIIRHFHDADKPIACICHGIQILAEAG--ILEDKKCTTVgfCEPDVRKAGGhfidTG 164 Legionella pneum...
CAC11607     78 DALIIPGGRAPEYIRNDkdf--irIVKYFFEKHSPVAELCHAPLALAAAG--VLKGRTTAAYpaLAPDVAIAGGq---FV 150 Thermoplasma aci...
NP_104378    82 DAVYAAGGRGPEYIRIDkrv--qaLVRHFHEAGKPIFTICHGVQILIAVDg-VVRGREVAALhyCEPEVTLAGGiyidVA 158 Mesorhizobium lo...
NP_558487    86 DGLVIPGGRMPEYVRVVasedvkrIVRHFFEAGKPVAAICHAPQILAAVG--VVNGRRMTSYiaVKPEVENSGGi---WV 160 Pyrobaculum aero...
CAD76517     98 AGIFFSGGRAPEYIRYDedl--vrITQHFFDTNKPIASVCHGVEIPAYAD--RVRGRRMATVakCQFDLEVCGGi---FV 170 Rhodopirellula b...
YP_005057    79 QGLYIPGGRAPEWIRTEpka--leIVRHFFQANKPVGTLCHGPLVLTAAG--VVKGRRLAAYgvLKPDIEMAGGt---FV 151 Thermus thermoph...
YP_147291    78 DALVIPGGRAPEYIRLDenv--qrIVRHFFEANKPIAAICHASLIFETMPd-LLKGRSLTAYiaCKPGVEALGAt--yVS 152 Geobacillus kaus...
YP_177000    78 AGLIIPGGRAPEYIRIHeht--aaIVNHFLDNNKPVGAICHAVQVLAAVAgdRLKGRALTAYtaCEPDVKALGAe---FR 152 Bacillus clausii...
ZP_00527128  78 AAILLLGGRAPEYLRNNaql--leLARDFDRQGKWIFAICHGVQILAAAG--LAKGKRVTCYehVRLEVELSGAt---WH 150 Solibacter usita...
ABA94527    287 ACVVVPGGRAPELLATRgea--vaLVREFAGKGKVVASIDQGHLLLAAVG--LLDGRSCASGvaTRVVAGLAGAa--sVR 360 Japanese rice
Feature 1                                     
YP_095993   165 MDGVVVDgkLVTGATWLGNAPWMRAFLHIL 194 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
CAC11607    151 DGAAVIDgnLVSARAWPDHPEWMRAFIKLL 180 Thermoplasma acidophilum
NP_104378   159 PTGAHVDgnLVSAKGWPGLSNFIRECLKVL 188 Mesorhizobium loti MAFF303099
NP_558487   161 DQEVVVDgnLVTSRAWPDNPAWMREFIKLV 190 Pyrobaculum aerophilum str. IM2
CAD76517    171 DEPCVIDgnLVSGRTYRDNGFYIAPWIQQL 200 Rhodopirellula baltica SH 1
YP_005057   152 DDAPVVDgnLVTGRAWPDNPAVLKAFIRLL 181 Thermus thermophilus HB27
YP_147291   153 DNTVHVDgnLVSAHAWPDLPAFMREFLRLL 182 Geobacillus kaustophilus HTA426
YP_177000   153 KETVYVDgnLVSGHAWDDLPQFMREFLKLT 182 Bacillus clausii KSM-K16
ZP_00527128 151 TDQTVRDgrVVTAQTWQSHPSFYREIFALL 180 Solibacter usitatus Ellin6076
ABA94527    361 HGGAVADgkLVTAASWPDLAEFIAHIISLL 390 Japanese rice

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