1ONS,1PV2


Conserved Protein Domain Family
GATase1_EcHsp31_like

?
cd03148: GATase1_EcHsp31_like 
Click on image for an interactive view with Cn3D
Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31)
Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31). This group includes proteins similar to EcHsp31. EcHsp31 has chaperone activity. EcHsp31 coordinates a metal ion using a 2-His-1-carboxylate motif present in various ions that use iron as a cofactor such as Carboxypeptidase A. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with a typical GATase1domain, a reactive Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. This Cys together with a different His and, an Asp (rather than a Glu) residue form a different catalytic triad from the typical GATase1 domain. EcHsp31 is a homodimer.
Statistics
?
PSSM-Id: 153242
View PSSM: cd03148
Aligned: 4 rows
Threshold Bit Score: 431.603
Threshold Setting Gi: 42543311
Created: 20-Oct-2005
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
 
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1:conserved cys residue [active site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                     
1ONS_A     50 ILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAgFEFEVATISGLmtKFEYWAMPhKDEKVmpfFEQHKSLFRNP 129 Escherichia coli
1PV2_H     51 ILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAgFEFEVATISGLmtKFEYWAMPhKDEKVmpfFEQHKSLFRNP 130 Escherichia coli
NP_371075  55 VLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAgFDVDVATLSGYpvKLELWAMPtEDEAVistYNKLKEKLKQP 134 Staphylococcus aur...
EAA71936   52 ILMIGTQERYLKMADGKFFSTGNHPVEMLLPMYHLDAAgFDIDVATLSGDpvKFEMWAFPkEDEAVkaiHDKYKQKLRSP 131 Gibberella zeae PH-1
Feature 1                                                            #                        
1ONS_A    130 KKLADVVASLnad-seYAAIFVPGGHGALIGLPESQDVAAALQWAIkndRFVISLCHGPAAFLalrh-----gdnPLNGY 203 Escherichia coli
1PV2_H    131 KKLADVVASLnad-seYAAIFVPGGHGALIGLPESQDVAAALQWAIkndRFVISLCHGPAAFLalrh-----gdnPLNGY 204 Escherichia coli
NP_371075 135 KKLADVIKNElgpdsdYLSVFIPGGHAAVVGISESEDVQQTLDWALdndRFIVTLCHGPAALLsagln---reksPLEGY 211 Staphylococcus aur...
EAA71936  132 LNLSEVWGKGftqdtpYIAVFIPGGHGVLNGIPFSKTVGDVLRWADannRFFITLCHGPASILaadvgkpegtkfIYEGY 211 Gibberella zeae PH-1
Feature 1                                                                                
1ONS_A    204 SICAFPDAADkqt-peIGYMPGHLTWYfGEELKKMGMNIINddiTGRVHKDRKLLTGDSPFAANALGKLAAQEML 277 Escherichia coli
1PV2_H    205 SICAFPDAADkqt-peIGYMPGHLTWYfGEELKKMGMNIINddiTGRVHKDRKLLTGDSPFAANALGKLAAQEML 278 Escherichia coli
NP_371075 212 SVCVFPDSLDeganieIGYLPGRLKWLvADLLTKQGLKVVNddmTGRTLKDRKLLTGDSPLASNELGKLAVNEML 286 Staphylococcus aureus s...
EAA71936  212 SVDVFPDSLDeganidIGYIPGKMDWLvGERLKKLGVTPINktiSGECHRDRLLLTGDSPLASNNLGKLAAKTLL 286 Gibberella zeae PH-1

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap