Conserved Protein Domain Family
GATase1_ScBLP_like

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cd03144: GATase1_ScBLP_like 
Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP)
Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP). Biotin-apoprotein ligase modifies proteins by covalently attaching biotin. ScBLP is known to biotinylate acety-CoA carboxylase and pyruvate carboxylase. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, the Cys residue found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow in a typical GATase1 domain is conserved.
Statistics
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PSSM-Id: 153238
View PSSM: cd03144
Aligned: 21 rows
Threshold Bit Score: 79.9868
Threshold Setting Gi: 67930477
Created: 21-Oct-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
conserved cys
Feature 1:conserved cys residue [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
CAA65617      2 NVLVYNgpgt-------tpgSVKHAVESLrdflep-------yyavstVNVKVLQTEpwm---------sktSAVVFPGG 58  baker's yeast
XP_652823     5 SIVIYAdegtid---vcvyySIKMLHSQYqeaq------------irkIYSNELIEGkwi---------yetDLFVMPGG 60  Entamoeba histol...
NP_396436    31 RVAVYRgpasce---dcsetMRKSIMALG-------------------PEYSVDYVGaeekidisdetlskfDIYVQPGG 88  Agrobacterium tu...
NP_445185     5 QVLVYCsegv-------spyYLRHTIRFLkyystqe-----gafdilrVDGNFLIKNpfwe--------ettRLLVFPGG 64  Chlamydophila pn...
ZP_00153715   2 KIKIYNdlgv-------skeSIKHCVHTLrlyapk--------ynvdyITAQEIIDEkwv---------qntLLLILLGG 57  Rickettsia ricke...
EAA71251     13 KAVVYRgpas-------spgCPEAIGNLLes---------------ssYHFKVIYAGpnesvdvtdetlqgaAIYAHGGG 70  Gibberella zeae ...
ZP_00268227   6 QVAVYIdega------vfedLLREIAREMdhdra---------rlrpiLAEDILAAGnpw---------ertLSLIVPGG 61  Rhodospirillum r...
CAH64065     17 KILVYSdegv-------spyYLRHLMRWLrnslsteenldicrvngnfLLYDPLWELs-------------aKLLIVPGG 76  Chlamydophila ab...
ZP_00460754 135 VALVYRgpaa-------cdgCPETIAARLre---------------sdYRFRVIYVGpaeplkitpaalagaALYVQPGG 192 Burkholderia cen...
ZP_00523649  33 SILLFNgtgasandvdaveaILKNNHLSYs-----------------tAKSSELNGMdqsr-------irqyRLLIFPGG 88  Solibacter usita...
Feature 1                                        #                                              
CAA65617     59 adlpyvqa---cqpiisrLKHFVsKQGGVFIGFCAGGYFGtsrvefaqgdptmevsgsrdlrffpgtsrg----payngf 131 baker's yeast
XP_652823    61 adrpfhkk--lngkgvevLKEFI-NDGGKYLGICAGAYFAssfiefnkdvaneltlceertlklfngiah---gpmyqgf 134 Entamoeba histol...
NP_396436    89 gqdipaafeslgeqrveaIRRFV-EAGGGFFGSCMGAYLAsgsgigliddelesevgrpgf------------------- 148 Agrobacterium tu...
NP_445185    65 adrpyhrv--lhglgtarIFQYV-SEGGNFLGICAGAYFGskmiyfyepegaplqgardlgffpgtakgp----ayrgnf 137 Chlamydophila pn...
ZP_00153715  58 rdlyyvqk--lqgkgnanIKNYI-KNGGNFLGICAGSYYSgnyvefakgtnieviskrelkifngtvrgpllapyyynsh 134 Rickettsia ricke...
EAA71251     71 pnwdkayr--qtkkyqrtIQKFV-GNGGHYMGFCLGAYLAgpndgydllprgvetdqeierrgaqv------------kd 135 Gibberella zeae ...
ZP_00268227  62 adspycaa--lngegndrIRAFV-AGGGGYLGICAGAYYAcreiafhagradavvgrrdlsllaaraigs---lsalapp 135 Rhodospirillum r...
CAH64065     77 adrayhki--lhglgtarIDNYI-REGGSYLGICAGAYFAcrrlsfnepdgslyeadrglgffpgravgp---aygkvfs 150 Chlamydophila ab...
ZP_00460754 193 gqdipgaaasigrhairaVRQYV-ANGGRYLGLCMGAYLAgaqgfglvagdidsevdrpgs------------------- 252 Burkholderia cen...
ZP_00523649  89 nfvamgns--ltagatesIRKAV-HGGLNYLGICAGGFLAgkynspynglnltsgvqfgfyaa----------------- 148 Solibacter usita...
Feature 1                                                                                       
CAA65617    132 qynseagaravklnlpdgsqfstYFNGGAvfvda-----------------------------------dkfdnVEILAT 176 baker's yeast
XP_652823   135 eeysergaviipiyyqnnekvelYYNGGCsfvdnlnqykeshflakypngmnalffdiigkgkvilsgphfeldIEWCGK 214 Entamoeba histol...
NP_396436   149 --pvssiistavstswngekqtvFFQDGPymsepkdirgfkkiat--------------yqngdiaaaryhfgnGIVVLT 212 Agrobacterium tu...
NP_445185   138 syvspsgvrvspqlfsdfglgyaMFNGGCffegsegypgvniesryddlpg--kpasivsrivskglavlsgphIEYLPH 215 Chlamydophila pn...
ZP_00153715 135 kgaraaylkinptlnlnikdcyaFYNGGGyfida-----------------------------------entkdTKIIAS 179 Rickettsia ricke...
EAA71251    136 eddtviqvdwtfesgktdkkrwmYFQDGVvikgl-----------------------------------saktpGHVIGR 180 Gibberella zeae ...
ZP_00268227 136 ydrtlasaaavrldwpglgvfrgHYHGGPrfeid------------------------------------pgaaITVLAR 179 Rhodospirillum r...
CAH64065    151 ytspigvraspllfsnfprrgwaLFNGGPyfehadtypdiciearyedlpn--qpaaiisrrlekglvvlsglhIEYLPE 228 Chlamydophila ab...
ZP_00460754 253 --tlhgiadtvtpvvwrgkkrwiYYQDGArlpva-----------------------------------plgsgGIVLAI 295 Burkholderia cen...
ZP_00523649 149 -egrgirktavpialtgastldqYWEDGPefsgwgavigkyp-------------------dgtpaivegtfgsGWVLLS 208 Solibacter usita...

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