1T0B


Conserved Protein Domain Family
GATase1_ThuA

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cd03142: GATase1_ThuA 
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Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA)
Type 1 glutamine amidotransferase (GATase1)-like domain found in Sinorhizobium meliloti Rm1021 ThuA (SmThuA). This group includes proteins similar to SmThuA which plays a role in a major pathway for trehalose catabolism. SmThuA is induced by trehalose but not by related structurally similar disaccharides like sucrose or maltose. Proteins in this group lack the catalytic triad of typical GATase1 domains: a His replaces the reactive Cys found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. S. meliloti Rm1021 thuA mutants are impaired in competitive colonization of Medicago sativa roots but are more competitive than the wild-type Rml021 in infecting alfalfa roots and forming nitrogen-fixing nodules.
Statistics
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PSSM-Id: 153236
View PSSM: cd03142
Aligned: 5 rows
Threshold Bit Score: 413.083
Threshold Setting Gi: 55230819
Created: 28-Sep-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1T0B_A     10 VVVWNEFRHEKKDeqvraIYPEGmHTVIASYLAEAg---FDAATAVlDEPEHGLTDEVLDrcDVLVWWGHiaHDEVkDEV 86  Geobacillus stearo...
NP_104286   5 AVVWGENVHEQTNaavrdLYPLTmHGTIAAALNQDk--gIEATTATlQEPEHGLSEKRLAatDVLLWWGHaaHGEVkDEI 82  Mesorhizobium loti...
AAV44979   36 VTVWNENVHEQEHeavadLYPDGiHGTIATALAERg---FDTETATlQEPEHGLTGDVLAetDVLTWWGHaaHDEVaDEV 112 Haloarcula marismo...
AAV46238   39 VTVWNENQHERATgpanaMYPDGiHTTLAETLTSYg---HTVQTATlDDPAHGLTETVLAetDVLLWWSDiaHDVVsDAT 115 Haloarcula marismo...
EAL94527    9 VTVWSENRHEKRDelvarLYPDGmHGAVKAGIEENlgakVSVRTATlDEPQHGLSEEVLAntDVLTWWGHmsHGDVeDEI 88  Arthrobacter sp. FB24
1T0B_A     87 VERVHRRVleGMGLIVLHSGHFSKIFKKLMGTTCNLKWREADEKERLWVVAPGHPIVEGIGPYIELeqEEMYGEFFDIPE 166 Geobacillus stearo...
NP_104286  83 VERVQKRVweGMGLIVLHSGHYSKIFKRLMGTPCSLKWREAGERERVWAINRGHPIAQGIGECLEIgeTEMYGEPFAVPE 162 Mesorhizobium loti...
AAV44979  113 VARVKERVldGMGLIVLHSGHYSKIFRELMGTTCSLKWREAAETERLWVVEPGHPIADGIDEYIELpeTEMYGERFDIPA 192 Haloarcula marismo...
AAV46238  116 ANRVEQAVrdGMGFIPLHSSHESKPFEALMGGTGTLRWREEGEREHVWVVEASHPITDGLPEEFELerAEIYGKGFDLPT 195 Haloarcula marismo...
EAL94527   89 VERVHRHVlsGMGLIVLHSGHWSKIFTKLMGTSCTLRWRSEQDRELVWTVDPTHPITRGVPHPIVIdqQEMYGEFFDIPT 168 Arthrobacter sp. FB24
1T0B_A    167 PDETIFISWFEGGEVFRSGCTFTRGkgkIFYFRPGHETYPTYHHPDVLKVIANAVRWA 224 Geobacillus stearothermophilus
NP_104286 163 PMETVFVSWYEGGEVFRSGLTYQRGagrIFYFSPGHETYPIYHNEGVQQVLRNAVHWA 220 Mesorhizobium loti MAFF303099
AAV44979  193 PDTLVFNSWFEGGEVFRSGCCYRRGagrIFYFRPGHETYPIYHNDAVQQVLANACEWA 250 Haloarcula marismortui ATCC 43049
AAV46238  196 PDTLVTVSWCDDGTVFPSGCCYYRDagrIFYFQPGHETFPVYHRPVVQKLLHNAVTWA 253 Haloarcula marismortui ATCC 43049
EAL94527  169 PEELVFISSFSGGEVFRSGCTFRRGhgkIFFFSPGDQDYPVYHHKDVRRVIANAVEWA 226 Arthrobacter sp. FB24
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