Conserved Protein Domain Family
GATase1_PfpI_3

?
cd03140: GATase1_PfpI_3 
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.
Statistics
?
PSSM-Id: 153234
View PSSM: cd03140
Aligned: 26 rows
Threshold Bit Score: 195.517
Threshold Setting Gi: 13473229
Created: 3-Oct-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
conserved cys
Feature 1:conserved cys residue [active site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
NP_388392     5 LFLILdq--yaDWEGVYLa-sALNQRe------dWSVHTVSLdp-iVSSIGGFktsvDYIIglep--anfNLLVMIGGDS 72  Bacillus subtili...
NP_786441     3 TALFLmldqyaDWEASYLa-sQLNQSt------dWQVKTTSTtp-lVTSIGGFttkvDYQLdcl---ptiDLLILIGGNS 71  Lactobacillus pl...
NP_722015     7 VYVFDgy---aDWEPSYVc-sELNRQds-----pFQIKTISLdkqpKTSMGGFrvmpDYDIsnyp--kkfKLLIIPGGDS 75  Streptococcus mu...
AAO76489      5 IFVLLne--faDWEGAFIa-aCLNQGvmpgspvpYKVKTLSItkepVSSIGGFrvlpDYDLkdmp--edyAGLILIGGMS 79  Bacteroides thet...
CAH08607      6 LFIILne--yaDWESAFLa-aSLHSGlmpgseikYVVKTVAPtleaVRSLGGFrtlpDYSFdtmp--sdyAGLVLIGGMQ 80  Bacteroides frag...
YP_330543     3 TAHILlldnyaDWEVAYIs-sTINMNe------eWTVKTISTqk-eVKSLGGMttriDYLLdevp--sqcDLLILIGGKT 72  Streptococcus ag...
ZP_00800327   8 VLLLLtdr-wcDWEAGYAi-aVINSFs------dYVVKTISTdtiaKVSMGNIkaevDYCIsnyeninnlAMIILPGGLS 79  Alkaliphilus met...
ZP_00237136   6 IFLFDgf---aEFEVNIAslfLISKQ--------FEIITATVdgktVTGEGGFlcqpHVSIeqik-iedyEVFIVPGGHI 73  Bacillus cereus ...
YP_037730     4 ILLFVypt-faEFEITVAt-aLLRNK--------YEIITAGLtkemIISETGLqvqpHIELgevr-veeyEGIIIPGGDA 72  Bacillus thuring...
YP_302588     4 ALFLLlde-faDWEGAYLs-sILNQDd------nWSVSTISVee-nVSSLGGFsvlvDYIIgdep--kdyDLLVMIGGNS 72  Staphylococcus s...
Feature 1                                 #                                                     
NP_388392    73 Wsn-dnKKLLHFVKTAFqkniPIAAICGAVDFLAknGLLNNHSHTGNfvylwkdykqy--kpissfvekqAVRDKNLVTA 149 Bacillus subtili...
NP_786441    72 Wni-nnSLLYSLVQQHLnaskPVGAICGAVDYLAqnGFLTGYQHTGNslamwhnypny--qnsadfheqqVISDKNLVTA 148 Lactobacillus pl...
NP_722015    76 WlagenTDILPVVDYAArqqiPIAAICAATSFLAenAYLDHVKHTGNslefmkkgaps-yrgedfyverqAVSDGGIVTA 154 Streptococcus mu...
AAO76489     80 WfspeaELIAPLIEKAIkdkkVVGGICNASVFLAmhGFLNNVKHTSNtidylkqhvgerytgdsnyvdqqAVRDGKIITA 159 Bacteroides thet...
CAH08607     81 WqspeaERIFPIVQDAFekgkVIGGICNAASFLCahGFLNHVKHTGNtlavlkqwggerytnedgylekqAVGDKNIVTA 160 Bacteroides frag...
YP_330543    73 Wdn-dyPDIIKLLNFALkhniTIGAICGAVDFMArnGFLTNFKHTGNdlnlwnnfely--snkndfkfeqAVKDKNLITA 149 Streptococcus ag...
ZP_00800327  80 WeenehDEIAGFIQSAVksdvPIAAICGATLFLCknGFLNHVKHTGDslelfqsqkny--ngdslylpaqVVVDGGFITA 157 Alkaliphilus met...
ZP_00237136  74 FdhlenEQLLSIVNKLHkqnkWIAGICAGTSLLHaaGVLNKKKFSTSltsdekqlahl--heweykqnkdVTVDGKIITA 151 Bacillus cereus ...
YP_037730    73 IhmedaEVLFSVIRQFHeqekLVAAICAGPYALAkaGLFKENSYTVTmdyrkldcf-----pvenfvyeeVVQHSNIITA 147 Bacillus thuring...
YP_302588    73 Wdn-nsENLLKFVEEAFnkniVIGAICGAVDYLArnGFLNKYKHTGNsvyiwqnykky--kpeneflekqSVVDNMLITA 149 Staphylococcus s...
Feature 1                           
NP_388392   150 NGTAPIEFTNLILEMIDFDT 169 Bacillus subtilis subsp. subtilis str. 168
NP_786441   149 NGTAALAFTAAVLQLIHFQS 168 Lactobacillus plantarum WCFS1
NP_722015   155 NGTAALEFAREIFFLLHVKN 174 Streptococcus mutans UA159
AAO76489    160 NGTGQLEFCREILYALEADT 179 Bacteroides thetaiotaomicron VPI-5482
CAH08607    161 NGTGYLEFTRELLLALKADT 180 Bacteroides fragilis NCTC 9343
YP_330543   150 NGTAPIEFEQLILESINYAD 169 Streptococcus agalactiae A909
ZP_00800327 158 NETAAVEFAYYIFKALEVDS 177 Alkaliphilus metalliredigenes QYMF
ZP_00237136 152 VGSAYVEFATEIMKQLNLFN 171 Bacillus cereus G9241
YP_037730   148 QGHAFVPFGIAIASYFGVTN 167 Bacillus thuringiensis serovar konkukian str. 97-27
YP_302588   150 NGTASLEFTESILREIDFDS 169 Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap