Conserved Protein Domain Family
GATase1_AraC_2

?
cd03138: GATase1_AraC_2 
AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain
A subgroup of AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain. AraC regulators are defined by a AraC-type helix-turn-helix DNA binding domain at their C-terminal. AraC family transcriptional regulators are widespread among bacteria and are involved in regulating diverse and important biological functions, including carbon metabolism, stress responses and virulence in different microorganisms. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with typical GATase1domains a reactive cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.
Statistics
?
PSSM-Id: 153232
View PSSM: cd03138
Aligned: 35 rows
Threshold Bit Score: 175.912
Threshold Setting Gi: 58040618
Created: 20-Oct-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
conserved cys
Feature 1:conserved cys residue [active site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
NP_533959    11 VGLVLyrdcqIAMVHGITDLFAIAsvfsq------drggPKLRVSHwsmgesgefsr-------------chdtdpgvgh 71  Agrobacterium tu...
ZP_00137924   5 VGIVAidgvfASTLMQAKDFFHMAslrhgkqqglglqpaFRTRILSpdgqpvrsfsgd------------siavdgplaa 72  Pseudomonas aeru...
EAN08130     15 VSLVAipeavISTLSGIFDVINGPalmqtsg--delpkpFRVEIVGlregplelasgvp---------vtahrsvaevea 83  Mesorhizobium sp...
ZP_00653091   9 VIIVGfdgvlGSVLAGALDLFSFTgvswqrfldeaveprFDVQIASlggadircsnrli---------mrahcdiqevte 79  Psychrobacter cr...
ZP_00774656   8 VALLIfngawASTVYGSMELFHSVnlrrp------kdqqFHCDLVSadsqpvql-------------------yggqsiq 62  Pseudoalteromona...
ZP_00776909   5 VTLFAsenamGLSLGLTHDVLAFAs-------------tLQQRLLGqaieislvtvdgkptstfsglaitpdcaldevqd 71  Pseudoalteromona...
YP_132685     3 VGFVLynralITGVSLAAEMLSSAaslrdrk--tqreypFKIKLVApslnppkltagir---------lqpditfedddn 71  Photobacterium p...
YP_271427    17 VNLVIyphvlATGVTLPIEMLLAGeafarry--dksvlkLDTQFLSessvkiksragitmva----ditldsellvkstp 90  Colwellia psychr...
YP_339899    12 IAIAVyqhllITSLTLPIEMLRAGeafakghinkqnfrpLAIHLVAknlepisnrtgla---------ilpdcatsntpn 82  Pseudoalteromona...
ZP_00817671   4 VTIIGfngalASAITGMIDLFRLAgvtwarihgeqptawFRTRLLTedgepcrcingvtll------adgswqdvdelga 77  Marinobacter aqu...
Feature 1                                                           #                           
NP_533959    72 pDIFVVPGRltgpa----------eieeaEPYARWLLDRHa---qGATLAASCGGSFMIAAtGLLAARPATTHWLfaerF 138 Agrobacterium tu...
ZP_00137924  73 cDIVVLPAFwgdfda---------lerryPQIVPWLRRSHa---eGTALCGEATGVFWLAQaGLLDGKEATTYWRfyreF 140 Pseudomonas aeru...
EAN08130     84 tDIVIVPSIllgpeg--------wqkgryPELVDWCRAMHe---rGALLCSACSGIFLLAEtGLFDGVDATVHYGyartF 152 Mesorhizobium sp...
ZP_00653091  80 cDLLLIPTIgdsidk---------vlsqnSDLIPHIKRLAn---tKADIASNCSGAFFLAKaGLLDGKVATTHWGyaskF 147 Psychrobacter cr...
ZP_00774656  63 gDAVIGDEPynlimlahywgdfqhlteqyPSIPPWLAKQHa---kGARIAGVNSGIFWAAEaGLLDGGRATTYWRhlreF 139 Pseudoalteromona...
ZP_00776909  72 tDLIILHSIwgevdt---------llskqAALYPRLRTWHe---qGKPIMAAATGAYFLAEaGLLNDRISTTHWHkqadF 139 Pseudoalteromona...
YP_132685    72 fDIVVLPPMwgnpfs---------sisqsPTIIPWLIKQYq---hGAQLVATGTGVCWLAEtGLLDNQVATTHWYfyeqF 139 Photobacterium p...
YP_271427    91 pDIIIVPSLwrnprp---------vlkshEKLVAWLKHCWq---qGSTLIGVGTGVCFLAEsGLLDNHSATTHWHyveqF 158 Colwellia psychr...
YP_339899    83 cDLVIVPGIwrnprp---------vvrtnQNIVTWLGQSFt---nGSHIIGVGTGNCLLAEaGLLDGHPATTHWHyakqF 150 Pseudoalteromona...
ZP_00817671  78 dDLLIIPTIgapide---------alqtnSPLIQWLSQFQdatpgDVRVASNCTGSFLLAAaGLLDGREATTHWGfgdqF 148 Marinobacter aqu...
Feature 1                                                                                 
NP_533959   139 RERFPDVRLeid-kiVIEDg----------------dIITAGGLMAWTDLGLRIVDRLlGPSVMIETGKFLLID 195 Agrobacterium tumefaci...
ZP_00137924 141 AERFPNVLLnqe-khLTDAd----------------dLFCASGVTSACDLYIYLIERFcGGSVAQAVARDTLYE 197 Pseudomonas aeruginosa...
EAN08130    153 ASSFPDVCIhpe-rvLVVSgkr-------------eeLITSGASMTWHDLVLYLIARHaGTTVAQDVARFFALQ 212 Mesorhizobium sp. BNC1
ZP_00653091 148 KADFPLVDLqen-qfVTQSknhpksqpkidsahqsgnIFCAAGGSAFYDLGLLLIERYcGREISTQVAKTQIID 220 Psychrobacter cryohalo...
ZP_00774656 140 ELRYPKVQWqanqasVEHAr-----------------IYSSNGQNASMDLSLHLVEKFcGASIAAGLARDISFD 196 Pseudoalteromonas atla...
ZP_00776909 140 AKRYPKVDVra--erFITAtg---------------eLYCSAGMNAGLEILVYLISKLsSSLVGEAVEHAFLVD 196 Pseudoalteromonas atla...
YP_132685   140 TSRYPQVTLnrqasiTAANg-----------------LFCTGSINSQSEMILYLIAENyGQKIADTIETHYGHE 196 Photobacterium profund...
YP_271427   159 KRDYPQVDLkp--dfFITQse---------------rIYCAASLNALADIIVHLIAQHyGKEAAQNVERNFSHE 215 Colwellia psychrerythr...
YP_339899   151 SHDYPKVLLkp--dfFITQse---------------rLYTVASLNALADVIVHIISQYyGKAAAQHVERNFSHE 207 Pseudoalteromonas halo...
ZP_00817671 149 RRQFPAVNLhad-klVTVDg----------------pVACAGGGMAWWDLGVYLVERLaGAQVARELAKAFVID 205 Marinobacter aquaeolei...

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap