Conserved Protein Domain Family
GST_N_etherase_LigE

?
cd03038: GST_N_etherase_LigE 
GST_N family, Beta etherase LigE subfamily; composed of proteins similar to Sphingomonas paucimobilis beta etherase, LigE, a GST-like protein that catalyzes the cleavage of the beta-aryl ether linkages present in low-moleculer weight lignins using GSH as the hydrogen donor. This reaction is an essential step in the degradation of lignin, a complex phenolic polymer that is the most abundant aromatic material in the biosphere. The beta etherase activity of LigE is enantioselective and it complements the activity of the other GST family beta etherase, LigF.
Statistics
?
PSSM-Id: 239336
Aligned: 17 rows
Threshold Bit Score: 108.588
Created: 22-Feb-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
Feature 1:putative GSH binding site (G-site) [chemical binding site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                        #                                               ###            
P27457        7 ITLYDLQLESGc-TISPYVWRTKYALKHKGFDIDIVPGGFTGILERTG-------------GRSERVPVIVDD---GEWV 69  Sphingomonas pau...
NP_949676    39 LKLFELVGADAgrPFSPFVWRTRMALAHKGLTAETIPWRFTDKAAIAP-------------YGSEKVPVLLDG---DKVV 102 Rhodopseudomonas...
XP_330076     8 ITFFDIPSKDGr-TWTLNPWKTRFALNYKSLPYHTQWLEYPDIRPTLSphlppa--apepsTSSYTIPAIRFPd--GTYM 82  Neurospora crassa
EAA64076      8 ITFYDIAMRTPslSCSPNPSKTRLALNFASVPYKTTFVPLPSIPSVRQslgvpagrqfadgSDFYTLPVIVDEv-tGSKI 86  Aspergillus nidu...
EAA69826      9 IILYDLACTKNv-CFSPVVWKIRLMFNYKKIPYQTIFLEFPDIAPTLEelglpshspgtgsHVNYTVPAIKHVp-tGAYI 86  Gibberella zeae ...
ZP_00418707   2 RELYELRGSSPevLFSPYCWRVRLALAHKGLDFVSRPVRFTDKEALAF-------------SGQTLVPVLRDG---ETTV 65  Azotobacter vine...
ZP_00632920  17 IALYSLCAADGvrHYSPHVWKAILALRHKGLEFDLRPVSFADIPRIAG-------------GGFDSVPVLDDR---GHRL 80  Paracoccus denit...
BAB68404      6 YVLFDLPSRDPvgAWSLNPWKTRFLLNFKGIDYKTEWLEYPDIKPTLEphvp-----anpsTGTWTIPTVKFPd--GEYI 78  Gibberella fujik...
BAA87709      3 IILYDLVGSSEeiRFSPHCWKTRMSLAHKGLEYQTVPTTFVGVPEVEG-------------GVSKTIPVIRDG---EQVI 66  Agrobacterium tu...
ZP_00671473   3 IKLYDLVAAEEnrAFSPFCWRIRMALAHKNLEVKIIPWRLTEKEAIAF-------------SNQETVPVIVDGnkgDKVV 69  Trichodesmium er...
Feature 1        ##            
P27457       70 LDSWVIAEYLDEKYP 84  Sphingomonas paucimobilis
NP_949676   103 ADSWAIANYLEDAYP 117 Rhodopseudomonas palustris CGA009
XP_330076    83 MDSKPIAVALEERYP 97  Neurospora crassa
EAA64076     87 GDSFDIAIYLHERYA 101 Aspergillus nidulans FGSC A4
EAA69826     87 MDSPAIAKFLETTYP 101 Gibberella zeae PH-1
ZP_00418707  66 HDSLAIFRYLDERYP 80  Azotobacter vinelandii AvOP
ZP_00632920  81 GDSFGIALHLEAAHS 95  Paracoccus denitrificans PD1222
BAB68404     79 MDSNKILERVEKDHP 93  Gibberella fujikuroi
BAA87709     67 ADSFAIALYLDEAYP 81  Agrobacterium tumefaciens
ZP_00671473  70 ADSWNIANYLEETYP 84  Trichodesmium erythraeum IMS101

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap