Conserved Protein Domain Family
arch_FMN
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cd02911: arch_FMN 
Archeal FMN-binding domain. This family of archaeal proteins are part of the NAD(P)H-dependent flavin oxidoreductase (oxidored) FMN-binding family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN. The specific function of this group is unknown.
Links
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Statistics
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PSSM-Id: 239237
Aligned: 11 rows
Threshold Bit Score: 296.933
Created: 16-Aug-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Conserved Features/SitesClick to see Conserved Features Help
 
putative activeputative FMNphosphate
Feature 1:putative active site [active site]
Evidence:
  • Comment:Based on comparision to other members of the family
  • Citation:PMID 7881908
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                     #                                   #             
AAV45134      5 RVALASLSGEADASWAr-aVESHVGCAFLGGIALDDRTREAARAMTDRDRSEFlpdd--pvafVDDQLAALADapl---- 77  Haloarcula maris...
YP_448419     1 MNVLSAMAGICDGEFCkkfTKENIDIITLGGYNSDLETDTAGIENTKNNRQEFiikptelsshISKQVEIIRNynpswqg 80  Methanosphaera s...
NP_247112    14 KVVLAPMAGITDGDFCr-kFKDLFAIVTIGGYNLDSATYKASRDIEKRGRKEFsinleefnsyIIEQIKKAREsna---- 88  Methanocaldococc...
NP_069580     6 RLALSAMAGVNNAEFC---RKQKASLVILGGFNADRRALEAAEKAVKRGRKEFlfg----idgIEGEIKKLGRrk----- 73  Archaeoglobus fu...
YP_502142    17 PIAVACMAGITDGAYIr-nLADHIGLGIIGGYAIDEPTIKAARVLSDLGREEFlprn--lvddLKGQIALIKAagv---- 89  Methanospirillum...
YP_564972    68 PIALAPMAGITDSVFAs-kNAKNAGLAVIGGYNLDEETNAAAAKLVERGRQEFlsda--plefFETEVNAVDTgg----- 139 Methanococcoides...
CAJ38112     17 PVAVASMAGITGGDFFe--SCKDAGLYVMGGYSLDAATMAASREIAERGRKEFitdr--plelIEGDLKKVSGkgv---- 88  uncultured metha...
AAM04133     18 PIALAPMAGIVDGAFAn-qYAGDAGLVVLGAFNLDEGSIEVASKLVARGRKEFisde--pmelIKKEIRAVNSgs----- 89  Methanosarcina a...
CAJ53115      5 RVALASLSGEADATWAe-nGASDAGAAFIGGISLDTVTRDAARQLVDRGRCEFlpsd--piafITTELDALADvai---- 77  Haloquadratum wa...
ZP_01390663  20 PVAIASMAGIVDAAYVl-eRADHVGAAFIGGYSIDAPTIEASRRMAEEGRKEFlydd--pleaLGREIDALKEsdv---- 92  Methanoculleus m...
NP_987526    13 KIVLAPMAGITDGDFCl-kYTDTFGIVCLGAFNLDFDTDLASKKICNRGRKEFiydlieidqkISSEIEKAKKsns---- 87  Methanococcus ma...

Feature 1                                     # ##                                         #    
AAV45134     78 cpAFNVRSatLGPVERAAAVCQRHDAIIEINAHCRQDEMCAAGAGESLLREPD--RLAAFVEAAAStg--aTVSVKGRAE 153 Haloarcula maris...
YP_448419    81 liSVNLRG--IKPESFRVVKNNKNIDILEINAHCRQEAVVKAGAGEGLLKDKK--RLSQVLDEVSSyd--mDVSVKIRAN 154 Methanosphaera s...
NP_247112    89 lvSVNVRFvdIDEAYDKLLTIAKHADIIELNCHCRQPEITSLGIGQELMKNKN--LLKEFLTKMKEln--kPIFLKIRLN 164 Methanocaldococc...
NP_069580    74 -fAVNVRSssLEGYLNVAELVAEFEGIIEINAHCRQPEFVEIGCGEWLLFNHE--RLVEIVSKTSRi---aPTFVKIRGG 147 Archaeoglobus fu...
YP_502142    90 vpVINLRAs-EAGSLNALAQELGNSVIYEIDAHCRQQPMIDARSGEFLLHHPE--VLISYVQALKIag--vLVSVKIRAG 164 Methanospirillum...
YP_564972   140 avGFNVRAvsLEPLLKAATIVKDAGGILELDAHCRQEEMVSIGVGEALMKDLP--RLNEWIKKIKEtg--vVLSVKVRAN 215 Methanococcoides...
CAJ38112     89 aiGINVRAasLEPLIAAAKLAKKYGAILELNAHCRQEEMAAIGVGEVMLKDRI--GLSKTIVELKKtg--vVLSLKMRAG 164 uncultured metha...
AAM04133     90 vvAVNVRSttLEPLIEAAKIVKEEGAILELNAHCKQPEMLEAGIGEALLRDLP--RLSAWIKAIKEtg--vVLSVKVRAN 165 Methanosarcina a...
CAJ53115     78 tpGVNVRSttPEPVRVAGRHCAKYNAILEINAHCRQDEMCTVGAGETLLQDNEs-QLRELIKAGRAgg--aMVSVKVRAG 154 Haloquadratum wa...
ZP_01390663  93 vmGINLRGs-TPASYAEVARAFEDAVVYEIDAHCRQPAMLEAGCGEHLLRNPA--KLAEIIRALKAed--vTVSVKIRAG 167 Methanoculleus m...
NP_987526    88 lvSVNIRFndFSKAKSHIVEISKNADILELNCHCRQPEITYLNLGQNLLKFENesKLINFLENIQKlnleiPIFLKLRAN 167 Methanococcus ma...

Feature 1                                                               #                      #
AAV45134    154 ldgvSLPAVAQ-AIEDAGGD--VFHVDAMDSes-vIADVADATD-------LFVVANNGVRGTATTREYLSYgADAVSVG 222 Haloarcula maris...
YP_448419   155 vcgvDTLEITK-LIESYNID--YIHLDATNPgi-mEADYEIIEEvsn-nteIHLIGNNSVTTHDDYMKMINSgADSVSVA 229 Methanosphaera s...
NP_247112   165 ci-pLKELIDNlNYVRDYFD--GLHVDCFYPgk-pYADMDSLKIlaeefndKIIIGNNSIDSIEKAKEMLKY-SDFVSVA 239 Methanocaldococc...
NP_069580   148 hk-lDYEKIAR-KLFDAGCL--AIHVDAMIPg--gGCDFSLIERis---riGNVIGNNSFVDIESGERIIMAgAKMASAA 218 Archaeoglobus fu...
YP_502142   165 ia-aDDVELSR-LLWKAGAD--ILHIDLMDFd---HTHLKKIRDts----pIFIIANNGITTFEKAKEMFAHgADMISLA 233 Methanospirillum...
YP_564972   216 v--vDDIALAR-SIENAGAD--ILHVDAMKEg--aGADLRAILRird-strLLLIGNNSIMDIMDARDMFSKgADMISVS 287 Methanococcoides...
CAJ38112    165 i--vDEVPLLR-LLEKAGLD--IVHIDTMGTrgpnVNVLKKLRDgt----gLFIIGNNSINGYESAQAAYSAgCDMISLA 235 uncultured metha...
AAM04133    166 v--iNDIELAR-LIDKAGAD--IIHVDAMLEg--fGADLDAIVNyrd-atrLFLIGNNSVTDFATAKDMFSRgADMVSVA 237 Methanosarcina a...
CAJ53115    155 idgvDLTAIAR-TIADAGGE--IIHVDAMDT----EVSIKQIATaa---peLFIIANNGVRGHESVREYYGYgADAVSIG 224 Haloquadratum wa...
ZP_01390663 168 va-aDDAVLAR-TVWKAGAD--ILHVDLMDFg---HNKVRQIRNas----pLTLIANNSITTFDKAMDAFSHgADLVSLA 236 Methanoculleus m...
NP_987526   168 f--lKAEELIK-SLDKVRGYfdGIHIDCFNPgk-nHADLEYLKKirenfpeKIIIGNNSVNSVESAKEMLEY-ADFVSVA 242 Methanococcus ma...

Feature 1       #              
AAV45134    223 Ras-dKPETLDTVRE 236 Haloarcula marismortui ATCC 43049
YP_448419   230 Ra--aLNGNIQDIFY 242 Methanosphaera stadtmanae DSM 3091
NP_247112   240 Rt--iLKGNVEWIKE 252 Methanocaldococcus jannaschii DSM 2661
NP_069580   219 Rav-lRDENFFEKML 232 Archaeoglobus fulgidus DSM 4304
YP_502142   234 Rk--sDKKTLSTLYA 246 Methanospirillum hungatei JF-1
YP_564972   288 RvvleDDGFIDSLVE 302 Methanococcoides burtonii DSM 6242
CAJ38112    236 RpvleNPKIIKSLVT 250 uncultured methanogenic archaeon
AAM04133    238 RgameNPELISQLVE 252 Methanosarcina acetivorans C2A
CAJ53115    225 Rp--sTNRHVRRQVR 237 Haloquadratum walsbyi DSM 16790
ZP_01390663 237 Rq--sDTWTLAGLDA 249 Methanoculleus marisnigri JR1
NP_987526   243 Rc--vLSNNIEWINK 255 Methanococcus maripaludis S2

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