Conserved Protein Domain Family
GH18_chitinase_D-like

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cd02871: GH18_chitinase_D-like 
GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.
Statistics
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PSSM-Id: 119350
View PSSM: cd02871
Aligned: 22 rows
Threshold Bit Score: 279.991
Threshold Setting Gi: 50365163
Created: 1-Jun-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative active
Feature 1:putative active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1              #                                             #                            
P27050        190 KWLIGYWHNFdngstnik-------------------lrnvstaYDVINVSFAEpispgsgtla--------ftpynatv 242  Bacillus circ...
EAY70921       30 KILMGFWHNWpsdagqgyrggr----------faempltdipdaYNVVAVAFMKgqgiptfr------------pyntsd 87   Burkholderia ...
AAC46383       35 GVVVGYWQNWcdgggyqggna------------pcvtldevnpmYNIVNVSFMKvydvadgriptf----kldptvglse 98   Vibrio harveyi
CAC99961       44 QVLVGYWHSWkssgkdgyqqgt----------sadialkdtpkaYNVVDVSFMKgdgvnriptf---------kpvgind 104  Listeria mono...
YP_053588     782 KTLVGYHYDWggnfenkial---------------ndkdlltssYNVINLSFLYstveyqmpt-----------yspnnp 835  Mesoplasma fl...
YP_001196873 1142 KIILGYAHSWenagapfly-----------------fsqmvgskFNVVDYSFVEtvnrdgytpilttndtryltngvfnk 1204 Flavobacteriu...
CAB69724       52 KVLQGYWENWdgaangvhppfgw---------tpitdpqigahgYNVLNAAFPVilsdgtalwe--------dgmdrgvk 114  Streptomyces ...
AAN41259       41 KVLQGYWENWdgakngvhppfgw---------tpiqnpdirkhgYNVINAAFPIiqpdgtalwe--------dgmdtgvk 103  Beauveria bas...
YP_514418     359 AGILPLWGKSssynisgqqintipisismpkdkeycdynpnvckYNVIIAAYLTytsskgfelsfne--engsskkiysp 436  Francisella t...
ZP_03039479   193 HILTGYWQNFvngasklk-------------------vrdipdqYDIIVLAFAEmdpanpggvtfnvdsalsaalggyts 253  Geobacillus s...
Feature 1                                                                   # #                   
P27050        243 eeFKSDIAYLQSQGKKVLISMGGangrieltdatkKRQQFEDSLKSIISTYGFNGLDIDLEGSslslnagdtdf----rs 318  Bacillus circ...
EAY70921       88 aeFRRQIGALNARQRAVLISLGGadahi--elhtgQEDDLAHEIVRLVETYGFDGLDIDLEQSaidya------------ 153  Burkholderia ...
AAC46383       99 eqFIDQVSELNKQGRSVLLALGGadahv--eletgDERAFADEIIRLTERYGFDGLDIDLEQAavtaa------------ 164  Vibrio harveyi
CAC99961      105 sdFRAQVGALNKEGRAVLLALGGadghv--elkagDEEAFANEIIRQVETYGFDGLDIDLEQSaitag------------ 170  Listeria mono...
YP_053588     836 aaIKEGVKALQSQGKRVLISMGGataehm-kfrndQKDQLKTAIKSVINEYGFDGLDIDWESEslkss------------ 902  Mesoplasma fl...
YP_001196873 1205 qlLKNDIKSLRDSGVPVIVSIGGqnghvv-ldnvtQKNIFVNGLKAIIDEYQFDGVDIDFEGGsmnfnagglrdisyagi 1283 Flavobacteriu...
CAB69724      115 vaTPAEMCAAKASGQTLLLSIGGatagid-lnstaVADRFVDTIVPILKEYNFDGIDIDIETGltgsgni---------- 183  Streptomyces ...
AAN41259      104 vaSPADMCEAKAAGATILMSIGGataaid-lsssaVADKFVSTIVPILKKYNFDGIDIDIESGltgsgni---------- 172  Beauveria bas...
YP_514418     437 eeLKAFITYMNSKGKHTIVSIGGkys------hinWETINFSDLVKIVQEYGFNGINFDLSSSdmpkndkva-------k 503  Francisella t...
ZP_03039479   254 aeLIADIQAKRAQGKKVIISIGGelgninlnnpspNVANFVNSMYGIMTQYGLDGLDIDLEHGmnv-------------- 319  Geobacillus s...
Feature 1                                                                                    # #  
P27050        319 pttpkivnLINGVKALKSHFga---nfVLTAAPETAYvqggyl----nyggpwGAYLPVIHALRn---DLTLLHVQHYNt 388  Bacillus circ...
EAY70921      154 ---dnqtvIPAALRMVKDHYakerknfIISMAPEFPYlr------------qnGKYVPYIKALEg---YYDFIAPQYYNq 215  Burkholderia ...
AAC46383      165 ---nnqtvIPDALKLVKDHYraegknfLITMAPEFPYlt------------tgGKYVPYIDNLEg---YYDWINPQFYNq 226  Vibrio harveyi
CAC99961      171 ---dnktvIPAALKIVKDHYkaegknfLITMAPEFPYlk------------pgSAYESYLTSLAn---YYDYIAPQLYNq 232  Listeria mono...
YP_053588     903 ---esknvTAEALKELKDEYksegkdfIITMAPEFPYlrki--------keadGNYKEFLDGLDg---YYDWINPQFYNg 968  Mesoplasma fl...
YP_001196873 1284 sayprlknVVDAFKELKAYYgp---gfLLTAAPETQYvqggyt----tytdtfGSFLPIIQNLRn---ELDLLAVQLYNt 1353 Flavobacteriu...
CAB69724      184 --nqlsasQSNLIRIIDGVLarmpsnfGLTMAPETAYvtggsi----vygsiwGAYLPIIKKYAen-gRLWWLNMQYYNg 256  Streptomyces ...
AAN41259      173 --ntlstsQTNLIRIIDGVLaqmpanfGLTMAPETAYvtggti----tygsiwGSYLPIIKKYLdn-gRLWWLNMQYYNg 245  Beauveria bas...
YP_514418     504 iaadkinkLITALRQNNHGF-------WLTFSPEWHYivaplakndkdniyvnHNYIELLDSLGmnkiDYIWLNTFADKp 576  Francisella t...
ZP_03039479   320 ------pnLTNAIRQLKQKVgn---dfVLTMAPQTIDmqn-----------pnTSYMQLYNNLKd---MTTVINVQYYNs 376  Geobacillus s...
Feature 1                                                                                         
P27050        389 gsmv-----------------gldgRSYAQGTADFHVAMAQMLLQGfnvggss-----gpffspLRPDQIAIGVPASQQA 446  Bacillus circ...
EAY70921      216 ggdgvwv-----------dgvgwlkADDDEKKQDFLYYLTDSLVTGtrd------------ymrIPNDKFVIGLPSNPDA 272  Burkholderia ...
AAC46383      227 ggdgiwv-----------dgvgwiaQNNDELKEEFIYYISDSLINGtrg------------fhkIPHDKLVFGIPSSIDA 283  Vibrio harveyi
CAC99961      233 ggdgvwv----------detnqwiaQNNDTLKESFLYYMADSFINGtrg------------ylkIPANKFVFGLPANVDA 290  Listeria mono...
YP_053588     969 wgdgvlvetsedakktgvqqntyitNDNVDKRGEFYYLMSKYITSKpnnqn---------gfyqIPADKFIIGASTNEPA 1039 Mesoplasma fl...
YP_001196873 1354 ggen----------------gldgqYYGTAKKSNMVTALTDMVIKGyniast------gmrfdgLPASKVLIALPACPSA 1411 Flavobacteriu...
CAB69724      257 smy------------------gcagDSYSAGTVQGFTAQTDCLDKGlviqg---------ttvrVPYDKQVPGLPAQPGA 309  Streptomyces ...
AAN41259      246 emy------------------gcsgDSHKAGTVEGFIAQTDCLNKGlsiqg---------vtitIPYDKQVPGLPAQPGA 298  Beauveria bas...
YP_514418     577 ydgilsfy--------kdkdgehikITPADGYAKFLASLAWALTTRagydanmpkydeidkplhIPANKLVLMIPATKGT 648  Francisella t...
ZP_03039479   377 gcml-----------------grdgKCYSQGTVDFLTALSDLTLQW------------------VSPSQLGIGVPATSSA 421  Geobacillus s...
Feature 1                                                        #                                
P27050        447 ag--gGYTAPAELQKALNYLIKgvsyggsyt-lrqpagyvgLKGIMTWSINWDay-----------------tnNQFSNA 506  Bacillus circ...
EAY70921      273 aa-sgYVNNAQDAIHALERLENag---------------kaIRGLMTWSVSWDdgsdkn----------grpydWEFVRR 326  Burkholderia ...
AAC46383      284 aa-tgFVKEPQDLYDAFDSLTAqg---------------qpLRGVMTWSINWDmgtnka----------gqaynEQFIKD 337  Vibrio harveyi
CAC99961      291 aa-tgYVTDPQIVKNVFTRLQAkg---------------tpVKGIMTWSVNWDagknka----------gvpynNSFSNA 344  Listeria mono...
YP_053588    1040 g---rGAGSKEAFNKAYNLLNSdg---------------ikIRGLMTWSILFDafegmipdtyggtepkimwyrWSYSKW 1101 Mesoplasma fl...
YP_001196873 1412 ag--sGYLTPTEGINAMHYLRTgttfsgrtytmqpggpypsLRGLMTWSVNWDassc--------------gnsSELSKA 1475 Flavobacteriu...
CAB69724      310 g---gGYMSPSPVSQAWNHYNGa------------------LKGLMTWSLNWDgs-----------------knWTFGTN 351  Streptomyces ...
AAN41259      299 g---gGHMSPSNVAQVLSHYKGa------------------LKGLMTWSLNWDgs-----------------knWTFGDN 340  Beauveria bas...
YP_514418     649 thsdmVYVLSEKDIKEVVSLMKgnn--------------asFAGFAVWSIDFDatn---------------innGDLGND 699  Francisella t...
ZP_03039479   422 ag--gGYVSPTVVNNALNCLATgnscgsyk----paakypdIRGAMTWSINWDat-----------------tnYALAKT 478  Geobacillus s...
Feature 1             
P27050        507 HRPF 510  Bacillus circulans
EAY70921      327 YGFL 330  Burkholderia dolosa AUO158
AAC46383      338 YGPF 341  Vibrio harveyi
CAC99961      345 YGPI 348  Listeria monocytogenes
YP_053588    1102 FDES 1105 Mesoplasma florum L1
YP_001196873 1476 YAAY 1479 Flavobacterium johnsoniae UW101
CAB69724      352 VKSL 355  Streptomyces coelicolor A3(2)
AAN41259      341 VKGT 344  Beauveria bassiana
YP_514418     700 YSHK 703  Francisella tularensis subsp. holarctica
ZP_03039479   479 VRPF 482  Geobacillus sp. Y412MC10

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