1KSL


Conserved Protein Domain Family
PseudoU_synth_RsuA_like

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cd02870: PseudoU_synth_RsuA_like 
Click on image for an interactive view with Cn3D
Pseudouridine synthases, RsuA subfamily
Pseudouridine synthases are responsible for the synthesis of pseudouridine from uracil in ribosomal RNA. The RsuA subfamily includes Pseudouridine Synthase similar to Ribosomal small subunit pseudouridine 516 synthase. Most of the proteins in this family are bacterial proteins.
Statistics
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PSSM-Id: 211347
Aligned: 59 rows
Threshold Bit Score: 147.641
Created: 1-Aug-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
active site
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Comment:1KSL_A, PDB D102 is key conserved residue
  • Structure:1ksl_a, active site residues of E. coli RsuA

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                    ####                               
1KSL_A       65 YFXLNKPqGYVCstddpdhptvly--------fldepvawklhaAGRLDIDTTGLVLXTddGQWSHRItsprhhCEKTYL 136 Escherichia coli
P37765       69 VLAYYKPeGELCtrndpegrptvfd-------rlpklrgarwiaVGRLDVNTCGLLLFTtdGELANRLmhpsreVEREYA 141 Escherichia coli
NP_638299    65 TLLLNKPaGMSCeaavalatpqsrssldqteirvlkrhflrlsaPMPLDDEASGLLVLSqdGRILRRLtadaatIEQEYL 144 Xanthomonas camp...
ZP_00510945  65 YIALNKPvGYISsvkdqfgrktvm--------dlvkdikerifpVGRLDYDTSGLLLLTndGDFAYRLthpkheIKKVYE 136 Clostridium ther...
ZP_00522131  75 YILLYKPkGYLTtyrdpegrptvy--------allgdvgkwlspVGRLDLDTSGLLVLTndNDFAERItnpehkVPKTYQ 146 Solibacter usita...
ZP_00552315  66 YLLLNKPlGYVTtlkdpqgrptir--------rflkgipqrvypVGRLDVNSEGLLLLTndGALTQHLlhprhqVSKTYR 137 Desulfuromonas a...
NP_952455    65 YLILNKPvGYMTtlrdpegrpivt--------dllkgldvrvfpVGRLDYNTEGLLLLTndGAWANRLahprheVDKEYL 136 Geobacter sulfur...
YP_143485    64 VLALHKPkGYTTtrhdpharrtvf---------dllpkipglhpVGRLDRDSEGLLLLTndGDLTHRLthprfgVRKVYR 134 Thermus thermoph...
ZP_00397142 154 TFLLYKPaGYVTtardeygrrnvl---------samppipglhpVGRLDKDSEGLLLLTtdGQLTLTLthprygHEKAYR 224 Deinococcus geot...
ZP_00558039  76 YYLLHKPtGYITsvtdpqgrktvm--------elmpkiprrvypVGRLDYDTSGLLLLTndGDLAHRLmhpsygVEKTYR 147 Desulfitobacteri...
Feature 1                                                                  #                  
1KSL_A      137 VTLESpvaddtaeqfakgvqlhnekdltKPAVLEVITp------tQVRLTISEGRYHQVKRXFAAVGNhvvELHRERI 208 Escherichia coli
P37765      142 VRVFGqvddaklrdls--rgvqledgpaAFKTIKFSGgeg--inqWYNVTLTEGRNREVRRLWEAVGVqvsRLIRVRY 215 Escherichia coli
NP_638299   145 VEVRGelrpygmarla--sglvyqqrslPACKVSWQNe------eRLRFAIKHVQPGQLRYMCNEVGLdvvTIRRLRV 214 Xanthomonas campes...
ZP_00510945 137 ADLLGvpskddimrfk--nglwiddyftSPADFEILKsdg--kttKVRITIHEGKNRQVRKMCNKIGCpviRLKRISI 210 Clostridium thermo...
ZP_00522131 147 IKAATvlsdeqierlr--agvelsdgptRPAEVKRLRdgp--khtFLEMTITEGRNRQVRRMLEAVESkvsKLVRTAI 220 Solibacter usitatu...
ZP_00552315 138 VKVNGrispqacrqle--qgveledgvtAPAVVRNVHhsp--rnsWFDLEIREGRNRQVRRMCRGVGFevsALKRIRI 211 Desulfuromonas ace...
NP_952455   137 VRVRGavakeqirrla--tgvelddgptAPAKVEVSSqsd--nntWLSIVIHEGRYRQVRRMCEAVSLsvvRLRRVRY 210 Geobacter sulfurre...
YP_143485   135 VWTEGgtlpkevcrrlllgvdledgparALACRPAPG--------GAVLVLAEGRKREVRRMLQRVGYpvrRLLRLQV 204 Thermus thermophil...
ZP_00397142 225 AWTAGqpvaaelrvl---etgieladgpARALSARPAr------gGALVTLTEGRNRQVRRMLDAIGYpvhRLLRYRV 293 Deinococcus geothe...
ZP_00558039 148 VEVGEkipeqalkrle--kgvlledgktAPARIREVSpkgrgslpTYEITIHEGRNRQVRRMFKAVGFplsTLKRLRF 223 Desulfitobacterium...

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