Conserved Protein Domain Family
MopB_CT_FmdC-FwdD

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cd02789: MopB_CT_FmdC-FwdD 
The MopB_FmdC-FwdD CD includes the C-terminus of subunit C of molybdenum formylmethanofuran dehydrogenase (FmdC) and subunit D of tungsten formylmethanofuran dehydrogenase (FwdD), and other related proteins. Formylmethanofuran dehydrogenase catalyzes the first step in methane formation from CO2 in methanogenic archaea and some eubacteria. Members of this CD belong to the molybdopterin_binding superfamily of proteins. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region present in many, but not all, MopB homologs.
Statistics
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PSSM-Id: 239190
Aligned: 7 rows
Threshold Bit Score: 160.669
Created: 27-Jun-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
molybdopterin
Feature 1:molybdopterin cofactor binding site
Evidence:
  • Comment:defined by similarity to the molybdopterin-binding superfamily of proteins

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1     ## ####                                                                         
AAB85416  273 IKVIYNSGsTIREGQIIKGGnkltddyidecarCCISPEDYKLLGEP--ENVVVSSHGN--EVVLRAVedpg-iqmGTIF 347 Methanothermobacte...
NP_987630 290 LKVILNTGsTIEQGRIIKGGnkysheyldvcavCNMHPEDYILLGKP--EKVKVSSENGkySVLVRAEpned-vlrRNVF 366 Methanococcus mari...
NP_633592  15 MEVLLISGsTIDEGRLAKGGdkfteeytlecasCWISPADFVPLCSP--DKVKVTSRDGkhSIVVYAKctds-vqpGQVF 91  Methanosarcina maz...
NP_634005   3 IKANLISGrTADQGAHLEAKthkgyf--dacayCELNSADLEMLGASegDSLKVTTDFG--EVVVFAKaneg-npdGLAF 77  Methanosarcina maz...
Q58568      1 MKFFLNTGrTIWQGEAMEAGknldly-vkaagvVYINEEDMEKLGVKegDKVKVKSEYG--EVVVYVKkatermpeGMIY 77  Methanocaldococcus...
NP_070753   2 LEVEVISGrTLNQGATVEEKlteeyf--navnyAEINEEDWNALGLQegDRVKVKTEFG--EVVVFAKkgd--vpkGMIF 75  Archaeoglobus fulg...
CAA08782    1 MRVILNTGrTIWQGQAIESGkdlkmy-vdaaaiIQMNPEMMKQLGIAegDNVKVISEYG--DVVVKAVeakeplpeGMVY 77  Methanothermobacte...
Feature 1       #    #              ##      
AAB85416  348 IPRGIWANVLTPPyteSTGSPMYKGVPVYL 377 Methanothermobacter thermautotrophicus str. Delta H
NP_987630 367 IPRSVWANVIVDAysvSTGSPIYKGGTVYV 396 Methanococcus maripaludis S2
NP_633592  92 MPRAIWSNVVVDPdtlSTGSPLYKGAPVYI 121 Methanosarcina mazei Go1
NP_634005  78 IPMGPWANAVLDPdthGCGMPGFKGVPAEI 107 Methanosarcina mazei Go1
Q58568     78 IPMGPWANCVVKPdthSTGMPTFKGYPGFY 107 Methanocaldococcus jannaschii
NP_070753  76 IPMGPYANMVIDPstdGTGMPQFKGVKGTV 105 Archaeoglobus fulgidus DSM 4304
CAA08782   78 IPMGPWANRVIRPytdSTATPSFKNIPVEI 107 Methanothermobacter wolfeii

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