Conserved Protein Domain Family
MopB_1
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cd02762: MopB_1 
The MopB_1 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.
Links
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Statistics
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PSSM-Id: 239163
Aligned: 9 rows
Threshold Bit Score: 716.483
Created: 18-Apr-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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putativeputative
Feature 1:putative molybdopterin cofactor binding site [chemical binding site]
Evidence:
  • Comment:defined by similarity to the molybdopterin-binding superfamily of proteins
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                    #                                  
NP_827766     6 LRICPLCEATCGLTLTie-----gtRVTKARGDrddvFSKGFICPKGASFGAADGdpdRLRTPLVRed--geLREATWEE 78  Streptomyces ave...
ZP_00126545   7 YRACHLCEAICGLVIEtvveadsapRIASIKGDpldtFSRGHICPKAIALQDIQNdpdRLRQPMLRsg--dqWQPIAWQQ 84  Pseudomonas syri...
YP_116406    15 LRTCPLCEAVCGLEITlda----adHVVSVRGDkldpFSKGFLCPKGASLGKLDEdpeRVTEPMIRdratgaWRTAGWDE 90  Nocardia farcini...
AAV95124     12 HRSCNICEAMCGLIIThd-----gqDVLSIRPDpddpLSRGHICPKAVALQDFRTdpdRVTRPLLKrg--tdFEEISWEA 84  Silicibacter pom...
ZP_00376614   6 HRTCHICEANCGVLVEme-----grKVVSIKGNpdhvLSRGHICPKATAIADLQDdpdRLRRPVKRtd--tgWQELDWDT 78  Erythrobacter li...
NP_251404    10 KTACILCSLNCGLEVQte-----ngRISKIRGDddhpASQGYVCEKSQRMDYYQNgadRLDTPMRRrpd-gsYEAIDWDT 83  Pseudomonas aeru...
YP_103247     9 KTACILCSRNCGLVVDvt-----dgKFAKIRGDddhpVSKGYLCQKAARLTYYQHhddRLTHPLRRepd-gsFVRVTWDE 82  Burkholderia mal...
CAA17319      8 PTACILCECNCGIVVQvd-----drRLARIRGDkahpGSAGYTCNKALRLDHYQNnraRLSSPMRRrad-gtYEEIDWDT 81  Mycobacterium tu...
YP_119157     7 ARQCTLCEAHCGILVTve-----daKVTRIEGNpedvLSKGYICPKATAMGGLHHdpdRLRTPVRRvg--drFEPIGWDE 79  Nocardia farcini...

Feature 1                                                         # ###                         
NP_827766    79 AFDAVAAGLRPVveEHGPHAVGVVLGNPNVhtmAGALYPPVLLaglrthsLFTASTVDQMpkhvssgl-lygdavaiPVP 157 Streptomyces ave...
ZP_00126545  85 AFDLVAERLYAIqqRHGQNAVAVYQGNPSVhnyGLMTHSNYFLgllktrnRFSATSVDQLphhlssfl-myghgmllPIP 163 Pseudomonas syri...
YP_116406    91 AFDYIAERFPAItaEYGNQAVGMYVGNPNAhtvAGALYLPVLIralgtknLFSASTADQMpkqvaagl-mfgdpltvPVP 169 Nocardia farcini...
AAV95124     85 AFDHAAERIRAVqaAHDRDAVGVYLGNPNAhkfANLLNLPALVkaigtsnRYSSATADQIphhvasih-mlghpmlmPIP 163 Silicibacter pom...
ZP_00376614  79 AFREIAQKVVAL--QDAGARAAFYRGNPGAhdyALSTQSGYLQravgargTFSASTLDQIphhytqyq-myghvslaAVP 155 Erythrobacter li...
NP_251404    84 AIREVAEKFLAIkrRHGGESILYYGGGAQGn-hLGGAYGDSTLkal-gvkYRSNALAQEKtgefwvq---gkmfgtgVHG 158 Pseudomonas aeru...
YP_103247    83 ALDDIAQRLVALreRHGGDAFAFVGGGGQGn-hVGGAYSRQLLaam-rsrYAYNALGQEKtgdfwlngrlfgrqdchTTE 160 Burkholderia mal...
CAA17319     82 AIVEIAEGFKQIrdTHGGDKIFYYGGGGQGn-hLGGAYSGAFLkal-gsrYRSNALAQEKtgeawvd---fqlygghTRG 156 Mycobacterium tu...
YP_119157    80 AFAEIGRRLRAVraAHGPSAIGMYLGNPAAh-sSSVIYGVLLRtalltrnFFTASSIDQFpqefaawq-mfgsnllmPVA 157 Nocardia farcini...

Feature 1                 ## #  ##                          ###                   #             
NP_827766   158 DLDRTDHLLLLGaNPLESNGslctapdfpgKLKALKarggTLTVVDPRrTRTAKLADRHVAIRPGTDALLLAAMAYVLFE 237 Streptomyces ave...
ZP_00126545 164 DIDHTDFMLILGgNPLASNGsimtvpdvekRLKAIQqrggKLVVIDPRrSETAAIADQHLFVRPGGDAALLFGLLNTLFE 243 Pseudomonas syri...
YP_116406   170 DLDRTDYLLMLGaNPLESNGslctapdfpgRLAALRkrggRFVVVDPRaTRTAERADEHLFIRPGTDVFLLFGLVHTLFA 249 Nocardia farcini...
AAV95124    164 DIDRTDFLLIIGgNPVVSNGsmmtapgygrRIDAIKarggRVVVIDPRrTETAERAGEHHFIRPESDAWLLMAMLYVILS 243 Silicibacter pom...
ZP_00376614 156 DIDRSQLIVIVGgNPMASNGslwtvpdfrnRVKEMQarggRLVVIDPRnTETAKVADEWYPVKPGTDTALLAGILQCVLA 235 Erythrobacter li...
NP_251404   159 DFEHCEGAILIGkNPWQSHGfara---rvlLNAMAKdparSIIVIDPRlSETAALADFHLQIRPGTDAWCLAALVGIIVQ 235 Pseudomonas aeru...
YP_103247   161 DIEHADYVLVIGaNPYQAHGipna---rdtLRDLKKdparTLVVVDPRrSETAKFADLHLQVRPGADAYLMSAMLAIMLR 237 Burkholderia mal...
CAA17319    157 EFENAEVSVFVGkNPWMSQSfpra---rvvLNEIAKdpgrSMIVIDPVvTDTAKMADFHLRVQPGCDAWCLAALAAVLVQ 233 Mycobacterium tu...
YP_119157   158 DIDRTDRLVILGaNPAVSNGsvttmpgaklRIREVRkrggSVVVVDPRrTETARLADEHVAVAPGGDVYLLLAMLHVLVA 237 Nocardia farcini...

Feature 1                                                                   ####                
NP_827766   238 ERLVDLGELaph-vqGVDELADALRDFTPEAASPSCDVPADVIRELARELAAAPTAAVYGRIGSCTvphGTLASWLvdVL 316 Streptomyces ave...
ZP_00126545 244 EGLTRESHLpv---dGLEQVRQAIAGFTAEAMSPRCGIAAEQIRQLARDFAAADKAVCYGRMGVSTqtfGTLCHWLaqLI 320 Pseudomonas syri...
YP_116406   250 ENLTEVRVAv----nGLDEVRAAAAEFTPEVVAAHTGVPAETVVRLARELAAAPTAAVYARIGTCTaefGTLTQWLvdVL 325 Nocardia farcini...
AAV95124    244 DGPARLRHLepl-idGLDRLNAAVAPFTPERAAQATGIGAHSIRQLARDFAAAPRAACYARMGASTqsfGTLCQWAtnAL 322 Silicibacter pom...
ZP_00376614 236 DGDTLRDGLaelvddSWAQVKPAVDAFDLDTLANHCAVPADTIPTLAAELSSGKPAAIYGRMGVSVcefGALNQWLiqLI 315 Erythrobacter li...
NP_251404   236 DGLLARDWLaeh-tsGYEHIVDELNAIPVAYCAETCGVAEDKLRAAARRIASASSVSALEDLGMQMnlhSTLGSYLqrLV 314 Pseudomonas aeru...
YP_103247   238 DGLFDRAFIaqr-ctGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHtlhTTLNGYLekLL 316 Burkholderia mal...
CAA17319    234 ENLCNEAFLaah-vhGVDTVRAALQEVPVADYAQRCGVDEELLRAAARRIGTAASVSVFEDLGIQQapnSTVCSYLnkLL 312 Mycobacterium tu...
YP_119157   238 EGLCDERAVrdr-caGWDELRALVAEVTPEAMAPYAGVDAATIRRLAREHAAASSAVMYARIGVCQqvtGTLTHWLvnTI 316 Nocardia farcini...

Feature 1                         ##                                                            
NP_827766   317 NILTGNLDRPGGALFPLSATdkaprpagpgrgfal----grwhsrvsghpeakGELPLSALAEEIdtatgegspVRALIA 392 Streptomyces ave...
ZP_00126545 321 NLVTGNLDRVGGALCTEPAVdlvsstsgghfnr--------wqsrvsglpeygGELPVSALAEEMlvdg--egqVRALVT 390 Pseudomonas syri...
YP_116406   326 NVLTGNLDSPGGAMFATAAAtgivrskpfrtgr--------wrsrvrglgeamGELPVATLADEIltpg--egqIRAMVT 395 Nocardia farcini...
AAV95124    323 NIVTGNFDREGGAMFTTPAVdyvgmtsrrgkarsy----perrsrvsnqplynGEFPVSVLAEEIetpg--pgqIRALVT 396 Silicibacter pom...
ZP_00376614 316 NLATGNLDREGGTMFPQPLLdlvgqvgkgnikt--------vetargtlpsvmSEIPTIAFADELsrdd--dqrIRTLFV 385 Erythrobacter li...
NP_251404   315 WLLTGHYGRPGTSNAFVPFLslskaskgdtsmgkrgaprvekrspvanakiiiGLIPCNVIPEEIltdh--pkrYRAMLV 392 Pseudomonas aeru...
YP_103247   317 FLLTGHFGKRGGNNLHSFLLpvightderairhgk----plkrtahhrmfpiaGIYPPNILPDEIerag--ekrVRAAFV 390 Burkholderia mal...
CAA17319    313 WILTGNFAKKGGQHLHSSFAplfsqvsgrt--------------pvtgapiiaGLIPGNVVPEEIlteh--pdrFRAMIV 376 Mycobacterium tu...
YP_119157   317 NAVTGNLDSPGGQMFTTPPVdalrfarlsrvgyg------awtdstgmfksfrGELPVAVLAEEIrtds--pqrIRAMIT 388 Nocardia farcini...

Feature 1        ###                       ###  #           ##    #                             
NP_827766   393 VATNPVLSAPDGdrldkALGSLDFMVSVDPYLNETSRHAHVVLPPPPpSQAPHFD-FAFNAFAVhnQVRYTRAAVplepG 471 Streptomyces ave...
ZP_00126545 391 VAGNPVLSTPNGrqleqALEGLEFMLSIDLYINETTRHADLILPSTSaLENDHYDtTFNTLAVRn-VTRFNRAIFdkpeG 469 Pseudomonas syri...
YP_116406   396 VAGNPALSAPGAarldaALAGLDFMLSVDRYLNETTRHADVILPPPRtVQSPHYD-FALLQFAVrnYARYSRPLVpl-gD 473 Nocardia farcini...
AAV95124    397 VAGNPVLTAPNGrrierALQGLDFMMSLDIHVNDTTRHADLILPGTVaLEETVYDmVFHTFAVRn-TVGYAPPIFappqD 475 Silicibacter pom...
ZP_00376614 386 IAGNPVLSAPDGerteeALENLDLMVSMDMHITETSRHAHYILPPCGpLEKDHFTfFFGPLAVRn-FGAYSPPTLemeeG 464 Erythrobacter li...
NP_251404   393 ETGNPLHSLADSqrmreAMRALELSVVIDVAMTETARHADYVLPAASqFEKAEAT-FFNLEFPRn-AFHLRAPLFparpG 470 Pseudomonas aeru...
YP_103247   391 DSANPVVTYADTnayerAFGKLELLVVIDVAMTETARLAHYVLPAASqFEKWEAT-GFNLEFPAn-AFHLRHPLLpplgE 468 Burkholderia mal...
CAA17319    377 ERGNPAHSLADSaacraAFQALELMVVVDVAMTETARLAHYVLPAASqFEKPEAT-FFNFEFPRn-GFQLRRPLFpplpG 454 Mycobacterium tu...
YP_119157   389 YAGNPVLSTPQRgrlgaALDSLEFYVAVDMYVTETTRHADIILPPISqLEREDLN-FLFPVFSVrnNVRFDARVFeppaD 467 Nocardia farcini...

Feature 1                                                                                       
NP_827766   472 RMAETEILARLVLAAtgmhgaapdavdalvidqtlgkavtdp-------------------------hapvhgrdpgela 526 Streptomyces ave...
ZP_00126545 470 ALHDWEIFVGLASAFaakaeralk-------------------------------------------------------- 493 Pseudomonas syri...
YP_116406   474 RPSEAAVLARLGAALtgrphngtgdqdpvaavdelviag------------------------------mlhkagipdrr 523 Nocardia farcini...
AAV95124    476 NPPEWEVIARLTAKLtganqig---------------------------------------------------------- 497 Silicibacter pom...
ZP_00376614 465 AKADWEIAAELAQAIlaekgkpap-------------------------------------------------------- 488 Erythrobacter li...
NP_251404   471 TLPEAEIHARLLEAMgvlgekdyrplrlalklgrkafsaaflaaaatrpkvm----kyapvllyrtlgptlpagmeaaaa 546 Pseudomonas aeru...
YP_103247   469 SLPEPEIYTRLLEKMgelprrfplleriarfepraskhlaylgalgivlaankkwqrhaasivyrtlgralpgdaaasap 548 Burkholderia mal...
CAA17319    455 TLPEPEIWARLVRALgvvdeadlrplreaaaqgrqayteaflaaaatnptva----kltayvlyetlgptlpdglagaaa 530 Mycobacterium tu...
YP_119157   468 GLEDWQILARLVTELvplparrftgrllnalf--------------------------------------------evas 503 Nocardia farcini...

Feature 1                                                                                       
NP_827766   527 avltgdsgperrlDMMLRLGPYGdgfgarpdgltLEKVLAHPHGIDLGPLtprl-------pqpLKTRSGKVELLPGPIA 599 Streptomyces ave...
ZP_00126545 494 ----ptlppaqmiDRGLRAGLYGdass---hklsLETLDSHPHGLDLGALkanl-------aqrLKTANGRIQAAPEVIM 559 Pseudomonas syri...
YP_116406   524 deligansteqriDLMLRLGPYGewng---gtlnLQVLLDNPHGLDLGPLtprl-------pgaLRTASGAVELAPEPLL 593 Nocardia farcini...
AAV95124    498 ------ptpdqvlAVLLAQGFHGes-------vsLAGLQQTGRPLDLGALvpnl-------aerLETPDGRLDLAPQAFL 557 Silicibacter pom...
ZP_00376614 489 ----nfdtprerlDAMLKASPAGm---------sLAEVEAQPNGVDLGPLepcl-------knrLLTADKTLHAAPPELL 548 Erythrobacter li...
NP_251404   547 iwgicqlhvlnnrKTAARAGFDGlppla--adrlFQAMLDNPSGVVFAETtyae------swqaVARPEQRINLHIPELL 618 Pseudomonas aeru...
YP_103247   549 llplamlyaqrhyAAVRRAGFRGnratl--gtalFRAILERRSGTLISVHefde------mwrfIRHPDARVHLHIPEMI 620 Burkholderia mal...
CAA17319    531 lwglaqktamaypDAVRRAGHADgn-------alFDAILERPSGVTFTVHnyed------dfalISHPDHKIALEIPEML 597 Mycobacterium tu...
YP_119157   504 plrltalgmavgpHGVLRRGRKGv---------tVAKLRRTPGGVDLGPLqprlrsiiatkdrkVQLAPADFVSAAAELV 574 Nocardia farcini...

Feature 1             
NP_827766   600 GDLPRL 605 Streptomyces avermitilis MA-4680
ZP_00126545 560 ADLARF 565 Pseudomonas syringae pv. syringae B728a
YP_116406   594 DDLARL 599 Nocardia farcinica IFM 10152
AAV95124    558 DDLPRL 563 Silicibacter pomeroyi DSS-3
ZP_00376614 549 EELGRF 554 Erythrobacter litoralis HTCC2594
NP_251404   619 PELAKL 624 Pseudomonas aeruginosa PAO1
YP_103247   621 DELRAL 626 Burkholderia mallei ATCC 23344
CAA17319    598 AEIRSL 603 Mycobacterium tuberculosis H37Rv
YP_119157   575 AEARAG 580 Nocardia farcinica IFM 10152

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