Conserved Protein Domain Family
PurM-like2

?
cd02691: PurM-like2 
AIR synthase (PurM) related protein, archaeal subgroup 2 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.
Statistics
?
PSSM-Id: 100036
View PSSM: cd02691
Aligned: 9 rows
Threshold Bit Score: 439.902
Threshold Setting Gi: 156937218
Created: 6-Jun-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
putative ATPdimerization
Feature 1:putative ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
AAB86000      84 MGEMGVGSRGEGDFFVHRKIadivsstgtrsfinpeaqddggvvrtetgsgdVYITTAVDGIHSRLSeYPFLGGFHVTRA 163 Methanothermoba...
YP_001435014  69 AGEGGVGSRGLGDWAVHEALtslsgg--------------------gdaarvGDLVLAVDGFHSRLSsVPLLMGFHAVRA 128 Ignicoccus hosp...
CAA69526      72 AGEAGLGSRGIGDNLIHTKLfelagkqie---------------eyddagirENVVVSIDGIHSRLSyFPFLAGFYATRA 136 Sulfolobus solf...
YP_001192212  66 AGDSGLGSRGLGDNLIHLKLfelskrnle---------------tfddagivQDIVVSVDGIHSRLSyFPFLAGFHATKA 130 Metallosphaera ...
NP_614776     77 MGEMGVGSRGEGDFFVHELLtrlaakasegalvsp--eerddagavridpdeVILVSAVDGMHSRLSeFPFLAGFHATRA 154 Methanopyrus ka...
NP_071185     69 MGEFGVGSRGRGDFYVHEKIaevigdsgavvss------kdlddagvvkfgdFYISVAIDGIHSRLSeFPFIAGFHVTRA 142 Archaeoglobus f...
NP_615867     81 MGEFGVGSRGTGDFYVHSKLgevigqtgavvds------aqlddsgvvkignEYLVVTIDGIHSRLSdFPFLSGFHVARA 154 Methanosarcina ...
Q58811        79 MGRMGVGSRGEGDFFVHREIarivkstkvkayvs----aeeqddagivradaKYIVAAIDGTHSRLSdFPFLGGFHVTRA 154 Methanocaldococ...
YP_448523     74 MGEFGVGSRGQGDFYVHNQIaqiikntdtssivnp---taqddggvvkvedtYYITTAIDGIHSRLSdYPFLAGFHTARA 150 Methanosphaera ...
Feature 1           #                                             ###                            
AAB86000     164 ALRDVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSEtpp 243 Methanothermoba...
YP_001435014 129 AVRDVMVSGGAPVASLIDVHVADDTDVAYLLDVTAGAYVAGELTGAPLVGGSTLRIGGDAVIGNRVTGGAFAVGRKVrdw 208 Ignicoccus hosp...
CAA69526     137 TLRDIMVKGAYPLGLIVDIHLSDDSDIGMLIDFEAGVTTISKALDIPILAGSTLRIGGDLVLGDRISGAVGSIGILKskd 216 Sulfolobus solf...
YP_001192212 131 TLRDIMVKGAIPLGILVDIHLSDDSDVSMLFDFEAGVSTVADALNVPILAGSTLRIGGDMVLGERISGGVASVGRLQgep 210 Metallosphaera ...
NP_614776    155 AMRDVLVNGARPRGLLVDLHLADDGDVGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARpde 234 Methanopyrus ka...
NP_071185    143 AMRDVYVMGAEPVAVFSDIHIADDGDVSKIFDHIAGITAVCEAVKVPLVSGSTLRIGGDMVIGERMTGGVGCVGVSKhit 222 Archaeoglobus f...
NP_615867    155 ALRDVYSMGSRPLAMLSDIHVADDGDVAKIFDHIAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGITSslt 234 Methanosarcina ...
Q58811       155 ALRDIYVMGAEAVALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVGGDMVIGDRLVSAVGAIGVIKege 234 Methanocaldococ...
YP_448523    151 TLRDVCVMGANPVALISDIHLADDGDVGKILDYTAGICAVSELTQVPLVSGSTLRIGGDMVLGDRLVGAVGAVGSSNtlp 230 Methanosphaera ...
Feature 1                                                                                        
AAB86000     244 tar-kraepgDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIraSEAIMdsgLLGDVHAMTDVTNGGLRGDAHEIS 322 Methanothermoba...
YP_001435014 209 srf--naspgDELYATVGKGGGTVTAYALTHGRPELVKLTLNVDFV--YDIKRa-mEVECVKGAFDWTNGGIALDAFEIS 283 Ignicoccus hosp...
CAA69526     217 flr-krvkkgLKILMTEGNGGGTIATTAIYNGMPDVISETLNIKDLltCIIVRd-yLSSDVYSMTDVTNGGIRADALEVS 294 Sulfolobus solf...
YP_001192212 211 ftr-krisegQHIVMTEGHGGGTISSMAIFHGIEGVVEETLRVKDLeaCLAVRr--VRNLVSSMTDVTNGGIRGDALEIS 287 Metallosphaera ...
NP_614776    235 ltprrdaepgDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVraVEALReenLLSEVHAMTDITNGGIRGDATEIS 314 Methanopyrus ka...
NP_071185    223 prr--nvrdgDVILLTEGAGGGTVATTAIYFGMHEIVEETINLDFIkaVRAIFkadLVRRIHSMSDVTNGGIRGDAEEIA 300 Archaeoglobus f...
NP_615867    235 srn--rtrpgDLILMTEGAGGGTVSTTALYYGMHDVVEETINIRFLeaCEALLqsgLYKKVHSMTDVTNGGIRGDAREIS 312 Methanosarcina ...
Q58811       235 ptarrnaevgDVILMTEGSGGGTITTTALYYGWFDVIYETLNVDFIkaCQNLIrsgLIKKIHAMTDVTNGGLRGDAYEIS 314 Methanocaldococ...
YP_448523    231 kar-snakegDLILMTEGCGGGTITTTSIYNNYPEVIKETLNVQFIkaSQLLNnypSEDKIHAMTDITNGGIIGDSNEIN 309 Methanosphaera ...
Feature 1                                                                                        
AAB86000     323 STAGVGLEFDADAVmsmiNPSVLRMLQDLEIDPLGVSIDSLMIIApedvapdvmdtirgagvdVAEIGRVTDSGVpvl-l 401 Methanothermoba...
YP_001435014 284 RKLGVKVVLWKSVYea-vHPELLKAFEEDGIDPLRTSVDSVVFVAergc-----------elpFVKVGEVEAGEGv---- 347 Ignicoccus hosp...
CAA69526     295 KITNLSFVIDEEKFlsliNPKVRKMLNEINIDPFGISIDSILIFTdnpdlvkk--rlaqynirSEIVGYIDDFRQypi-- 370 Sulfolobus solf...
YP_001192212 288 EVTNVSLVIDEDEFlsliNPRIRKAMNELGIDPFGLSLDSILIFTnnpdevir--tlrdnhvqAKTIGEVTRRRGypi-- 363 Metallosphaera ...
NP_614776    315 ETAGVRLVFDEETVrslvNDRVLRMLDELDIDYLGLSLDMLMVIApedvaercvealngvgvrADVVGRVEEGSGvvl-e 393 Methanopyrus ka...
NP_071185    301 KVSGLALIFDYDKVrncvNPKVLKMLEELEIDFMGVSIDSLMVVCdaetaelvksavkeagvrIEEVGWVEKGRKgafvv 380 Archaeoglobus f...
NP_615867    313 KTAKVKMVFEEEKMrtlvNPKVLSMLEALKIDYLGVSLDALLVIAppeyageilktvraagveIDIIGRVEEGIGaei-i 391 Methanosarcina ...
Q58811       315 KTAKVSLIFDKEKVyktiNPKVLEMLEVLNIDPLGVSTDSLMIICpeeyadd-----ikkvtgAIEVGYVEEGEEsyl-v 388 Methanocaldococ...
YP_448523    310 KTTGLGIHLYSENIknliNSKVYNMLDDLDIDVLGVSVDSLMIIVseeesdtiirllnenkikTDVIGKITNTGKtyled 389 Methanosphaera ...
Feature 1                                          
AAB86000     402 rdGSEEELRPLFREAAYTQIKKMVGDKTPQDFEE 435 Methanothermobacter thermautotrophicus str. Delta H
YP_001435014 348 -yLEGEELEPAFREAPYTHSKRAVEGLERGADPE 380 Ignicoccus hospitalis KIN4/I
CAA69526     371 itYDGKELKPQFRESPYTPIKKYFGNYSPYSIEY 404 Sulfolobus solfataricus
YP_001192212 364 vtRDGREMRPAFRESPYTPIKAVIGNYSPMDLDE 397 Metallosphaera sedula DSM 5348
NP_614776    394 rdGEEVELDVKFRETAYTKVKRVIGEEHPEEFEE 427 Methanopyrus kandleri AV19
NP_071185    381 egGEIREIKPRFRESAYTPLKKVVGEETPPDFEE 414 Archaeoglobus fulgidus DSM 4304
NP_615867    392 vnGETRDFAPRFRESAYTPVKKIHGEDNPRDFEE 425 Methanosarcina acetivorans C2A
Q58811       389 dgNKKIPLKPMFRESAYTPVKKVVGERKPGDFEE 422 Methanocaldococcus jannaschii
YP_448523    390 esGNIKQLVPKFREAAYTPIKKVIDSINEVDFEE 423 Methanosphaera stadtmanae DSM 3091

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap