Conserved Protein Domain Family
R3H_AAA

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cd02645: R3H_AAA 
R3H domain of a group of proteins with unknown function, who also contain a AAA-ATPase (AAA) domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA or ssRNA in a sequence-specific manner.
Statistics
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PSSM-Id: 100074
View PSSM: cd02645
Aligned: 17 rows
Threshold Bit Score: 70.7707
Threshold Setting Gi: 88811456
Created: 28-Mar-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                      #   #                         
YP_063616    502 RILIETRIAIEKIVNGkkQSVELLSRNVNLRKLQHQLINFYnLRSRSFGeEPNRRLRIFP 561 Gracilaria tenuistipitata var. liui
P51281       505 QALQEAKLAIEIIILNenSIVQLTPRSAYIRKMQHNLIDNYqLRARSFGeEPYRKLRIYP 564 Porphyra purpurea
AAO42775     467 DALEEVRLAIEYIVIPggEPVELLPRRSDIIVRQLELVESYqLAVENLGtHLNPRLQILP 526 thale cress
YP_181509    450 LAIHEAEEAIAQVKSSh-IPVELSPQGAYIRRFQHIIAEKEhLSSHSLGkEPHRRVRISR 508 Dehalococcoides ethenogenes 195
BAB74008     519 DALEEARLAVEQIVIPkgQPVELLPRSPQVRKMQHELVEHYrLKSHSFGeEPNRRLRIYP 578 Nostoc sp. PCC 7120
XP_001759346 469 DALEEARVAVEQIVIPkvQAVELLPRSPEVLALQVKLVESYqLAWEKTGsGMNKRLRILP 528 Physcomitrella patens subsp. patens
YP_001543278 506 EAMEEVEEAISQVMDGstESIELSPQSSYVRRLQHQIVERYnLQSESTGkEPRRRIRIFR 565 Herpetosiphon aurantiacus ATCC 23779
YP_277334    495 SPLEETQFLIDEIIQSkkRAINLLPRSREVRKLQHQLISHYqLKSISVGvEPHRYVRLFP 554 Emiliania huxleyi
XP_001695856 480 PALEEAQVAVTEIVIPlhQPVELMPRARSVLEAQIKLLERYkLSHEIVGaGAEARIRILP 539 Chlamydomonas reinhardtii
ZP_01126711  446 EAAREAEQAAQRVLAQg-IAVELTPRSAPIRRMQHRIAMRHrLLAESAGsDPQRRLVLHP 504 Nitrococcus mobilis Nb-231

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