Conserved Protein Domain Family
GT2_SpsF

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cd02518: GT2_SpsF 
SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat.
Spore coat polysaccharide biosynthesis protein F (spsF) is a glycosyltransferase implicated in the synthesis of the spore coat in a variety of bacteria challenged by stress as starvation. The spsF gene is expressed in the late stage of coat development responsible for a terminal step in coat formation that involves the glycosylation of the coat. SpsF gene mutation resulted in spores that appeared normal. But, the spores tended to aggregate and had abnormal adsorption properties, indicating a surface alteration.
Statistics
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PSSM-Id: 133011
View PSSM: cd02518
Aligned: 44 rows
Threshold Bit Score: 230.151
Threshold Setting Gi: 42527422
Created: 28-Oct-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
ligand binding
Feature 1:ligand binding site
Evidence:
  • Comment:Putative ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           # #                                                                         
NP_348808     5 FCIVQARMGSERLQGK---VIKPILKKPMVIYTLDRLKksk----yidKIVLATSsmeretpLVESCEEYGYDVFKGSEA 77  Clostridium acet...
AAO76822      4 AFVVQARLGSTRLPGK---ILKPFYGNQSILDLMVHKLsai----sniPVIIATTnsvinepIEKKALALGVKCFRGEEN 76  Bacteroides thet...
NP_972520     9 AVIVQARLSSKRLVRK---ALLDLGGMPILYRVLDSVRelp-----aeHFILACDtns-kkeFQPIAESLGYLCIDGSEE 79  Treponema dentic...
NP_602502     7 AVIIACRLKSSRLKRK---ALLKIGTLSSIEMCIKNVLkfe----dtnSVVLATSiteedsiLKNYTYNKSVIFHQGDPD 79  Fusobacterium nu...
Q58463        4 IGIIQARTGSKRLKNK---VLLKLGDRCILEILLERLKksk----kldDIIVATTikkednaIVELCNSLGVNVFRGSEK 76  Methanocaldococc...
AAN47872     12 YAFIQARTGSSRLPEKvllEFPSGSGKTLVDRIYDRILtvl----pkeQIVYLIPked--keLRYFLNQRNYLFFAGDLL 85  Leptospira inter...
ZP_01687042   7 GIIIQARMGSSRLPAKialKLPYSGELSVIEHIIARSKavn----pdyLIAVATSvnaendlLAAMTSQQGVVLFRGDEE 82  Microscilla mari...
P39626        5 LFIIQARMGSTRLPGK---VLRPLGSNRLLDILVHRVRqsafyqkdrdNLVIATSdketddiLEAHCIKQGFRVFRGSEE 81  Bacillus subtilis
ABB30697      7 VAVIQARMGSSRLPGK---VLMTVAGKPLLEHIIDRLRrsr----tldDIVIATSdkpcddpLVDFAQTRGVTLVRGSED 79  Geobacter metall...
YP_012217     4 MAFVQARMGSTRLPGKs--LMPVWNGMGVLEMTLRRALrar----tlsGVVLCTStdpacdaLETLASGLGVQAFRGPED 77  Desulfovibrio vu...
Feature 1                                     #                                                 
NP_348808    78 NVLKRYEqaaeky----ganieDAVIRVTGDCPLIDPiivdnvv-tkflssdYDYVRLdv----pnTFVRGFDVEIFSMK 148 Clostridium acet...
AAO76822     77 DVLKRFIdvae-------yfdiQGIFRICSDNPFLDVhaarqlv-eiamkscNDYISFdidgtpsiKTHFGFWGEFVTLD 148 Bacteroides thet...
NP_972520    80 DVLRRFCdavefinsnfpnrplKAVIRVTADNPFLFVqaaeasirryfelgePDYFTYt-------GLPHGSGIEIIKAD 152 Treponema dentic...
NP_602502    80 DVIQRYIdiin-------kknyDVIVRVTGDCPYLSKdickfvl-dshfekgAEYSNGi-------GAAIGTNVEIMNSL 144 Fusobacterium nu...
Q58463       77 DVLDRFYnask-------fysgDVIVRITGDNPLTSIelidkqv-eyllknnFDYVSTk-------NIILGLSSEVFTFD 141 Methanocaldococc...
AAN47872     86 DVRRRYIeaah-------ffnaDSILRLTGDNPFYDTihldqll-qsfqffeSDLSYVs-------GLPLGMGGEIFTRK 150 Leptospira inter...
ZP_01687042  83 DVLSRYAaitq-------qyqlDTIVRLTGDNPCIDPvyiekai-eehathkADYTYTq-------GLPLGMNVEVVSNT 147 Microscilla mari...
P39626       82 RVLDRFVkvie-------avkpSVIIRLTGDNPFVDPelldvmi-qahfdqgSDYTYIl-------NAPLGICGEVVNAN 146 Bacillus subtilis
ABB30697     80 NVLLRFNkaae-------evdaDVIIRVTGDAPLVDPevmdrlv-rtllqegAEYCTIea-----gINSIHEGFCTFTRG 146 Geobacter metall...
YP_012217    78 DVLTRYAlate-------rfepDAVVRICADSPLVCPegidalv-affrdegLDYAAHamd---gtGLPDGLGCEVFTAA 146 Desulfovibrio vu...
Feature 1                                                                                       
NP_348808   149 ALktvnslinggkipkeeadmyKEHVTLYMYKhpneFKVGYVKgdef-----yskdYRLCVDTKEDFelvkniy----eh 219 Clostridium acet...
AAO76822    149 ALkrvigf--------tddllyREHVTNYIYShpelFNIQWISgspvv---skhhnIRLTIDTLEDFsvaqriyr--dlq 215 Bacteroides thet...
NP_972520   153 SLlkaase--------tddeyaHEHVSPAIYGhsdkYRCVRETappvw----yypeLRTTVDTAEDYekakeiykhlisn 220 Treponema dentic...
NP_602502   145 CLkeikky--------fpradySEYMTWYFQNnsevFKLNYVDlpnk-----wkrdYRLTLDYQEDLdlfnkvee--yfs 209 Fusobacterium nu...
Q58463      142 ALekawkn--------akekyqREHVTPYIYEnpnlFKVFYLEppeyl----kregIRLTIDTIKDFklylelq----kh 205 Methanocaldococc...
AAN47872    151 ALewtpnt---------leerhKEHVSLHIKEnsdrFRITKLSsllsekeklilpkLRLTIDEPKDFettsnifn--iln 219 Leptospira inter...
ZP_01687042 148 ALqiaheq--------gidqneREHVTYFVRQrpdqFVLHYPQvlsde---qdcaqYRLTLDTPSDYalmcllyq--qly 214 Microscilla mari...
P39626      147 LLidisriq-------aledqyQEHVTLYIRNhpalYRVQFLEaperf----rapqYRLTIDTKEDYesikalyq---ka 212 Bacillus subtilis
ABB30697    147 ALkrlmtea-------pddpvaIEHVTAYFIAhpdkFHIARIPvgneh----rfkgARLSVDTPADVqffdelyr--llg 213 Geobacter metall...
YP_012217   147 ALaqahae--------atapedREHVSLFIRHrperFRQATLAadaal----rapgVSLDVDTQDDLdalrrfima-lpp 213 Desulfovibrio vu...
Feature 1                                    
NP_348808   220 fndefVSSKNVIn--yLDRNSEIAQINND 246 Clostridium acetobutylicum ATCC 824
AAO76822    216 ekrveISIEVIVd--yVRRHAEYIQLMKQ 242 Bacteroides thetaiotaomicron VPI-5482
NP_972520   221 kkavpFTPADIVe--aVSYADRLVVFCPS 247 Treponema denticola ATCC 35405
NP_602502   210 knninYTIDNLFe--fLDKNPEISKINLN 236 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
Q58463      206 fdlinVDIRQIId--fLDKNPQIKNINSN 232 Methanocaldococcus jannaschii
AAN47872    220 eqnpiFGARECIn--lFEIDPNVFAGNQN 246 Leptospira interrogans serovar Lai str. 56601
ZP_01687042 215 shnhlFGFNEIMe--fFKENPWVKAINQD 241 Microscilla marina ATCC 23134
P39626      213 gerpdVSASELIt--lLNRNPDAATETRG 239 Bacillus subtilis
ABB30697    214 vpagdADIADVVr--lLRNNPHLLQINQH 240 Geobacter metallireducens GS-15
YP_012217   214 segpfWSADAIAplarGLHTPPQGTSMDI 242 Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough

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