Conserved Protein Domain Family
Ferritin_CCC1_C

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cd02431: Ferritin_CCC1_C 
CCC1-related domain of ferritin
Ferritin_CCC1_like_C: The proteins of this family contain two domains. This is the C-terminal domain that is closely related to the CCC1, a vacuole transmembrane protein functioning as an iron and manganese transporter. The N-terminal domain is similar to ferritin-like diiron-carboxylate proteins, which are involved in a variety of iron ion related functions, such as iron storage and regulation, mono-oxygenation, and reactive radical production. This family may be unique to certain bacteria and archaea.
Statistics
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PSSM-Id: 153122
View PSSM: cd02431
Aligned: 12 rows
Threshold Bit Score: 146.689
Threshold Setting Gi: 16081240
Created: 13-Apr-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_393546   147 NKDMIYGISDGLVEVLAALAGLTSIiv-snIDIALGGLVVGISGTASMSIGAYLSKKSETEyklveeekkilfrkk---- 221 Thermoplasma aci...
NP_343905   144 VGDFVYGISDGLVEVLAAVSGLSGAis-spLFVAVGGLIVGVSGTLSMAIGAYLSTKSEKDvkiqerkrleleknvdqhs 222 Sulfolobus solfa...
NP_377496   138 VSDFVYGISDGLVEVLAATSGLSGAfn-ipFLVGISGLIIGASGTLSMAIGAYLSTKSEKEinehkrrkieiqklvdrke 216 Sulfolobus tokod...
ZP_00311827 141 VGSMVLGLNDALVELTGTLAGLTFAlk-ntRLIALSGLITGIAATLSMAASEYLSARTEQEssr---------------- 203 Clostridium ther...
NP_559590   144 MGALVLGLADAIIEITGAHAGTLGTtn-ntVAAGVIGLIVGVGAAISMASASYLQTKHEVGks----------------- 205 Pyrobaculum aero...
NP_228307   128 VSSMVLGLNDALVELTGALAGLTFAfq-ntKIVGLSGLITGIAAAFSMAASEYLSQRAEEGsges--------------- 191 Thermotoga marit...
NP_148184   168 LGFIALGLADAIVEITGVHAGFLGAta-ttLVAGVAGLIVGLSAAISMAAAAYLQAKHESStta---------------- 230 Aeropyrum pernix K1
AAO75266    135 MGSVVLGLNDALVEFTGALAGFTLAls-dsKLIALTGSITGIAAALSMASSEYLSTKSEGDdkk---------------- 197 Bacteroides thet...
NP_661724   137 TGSIVLGLNDALVELTGALAGLTFAlq-ntRLVALTAVITGFAAALSMASSEYLSTKTEAGvks---------------- 199 Chlorobium tepid...
CAB50539    148 LRDFVLGMNDGLVEILGAVTGLSAVypnlpRLVGISGLIVGVAGALSMAIGALISVRSQRQvsesirnrtkiifqvsper 227 Pyrococcus abyss...
NP_622124   145 IRDFIMGMNDGLVEILGTVTGLSAVypknpITVGTAGLVVGVAGALSMAIGAYTSVRSQRQvnegikkkmellfkvsker 224 Thermoanaerobact...
YP_023568   143 SRDFLYGMSDGLVEVLAALTGLTAIid-nhILIALSGVVIGISGTFSMTLGAYLSQKTESDykitrikkinifnik---- 217 Picrophilus torr...
NP_393546   222 -------------------------------dvdmdyinsikseskTSALYVGVSYILGAAVPILPFVFLSk---yIALA 267 Thermoplasma aci...
NP_343905   223 vqlrlvnfftel---gvnlnlakkvslslvnvaedilypevkenpvKSALITGLSYITGAIIPILPYLIGLsg--lTGLI 297 Sulfolobus solfa...
NP_377496   217 vakklsmiltel---gireniasdispqlvdvaediiapkveespkKSAGVTALSYISGAVIPIIPYLLGIg---gLVGV 290 Sulfolobus tokod...
ZP_00311827 204 --------------------------------------------alKSSLYTGGAYVFTVACLVFPYLLFSny--vLSLV 237 Clostridium ther...
NP_559590   206 --------------------------------------------psVAALVTGVGYIAAVALMSLPYFLIHdv--yLAFA 239 Pyrobaculum aero...
NP_228307   192 -------------------------------------------kplKAAIYTGIAYIITVAVLVAPFLILKnp--fLSLV 226 Thermotoga marit...
NP_148184   231 --------------------------------------------plPSAIATGIAYFFAVVTLALPYFITHsn--iLAFV 264 Aeropyrum pernix K1
AAO75266    198 -------------------------------------------hpvKAAVYTGIAYLITVVSLVTPFILISnv--iVALG 232 Bacteroides thet...
NP_661724   200 --------------------------------------------pvKASIYTGVAYIIAVAVLIVPYLVLNdiylsLALA 235 Chlorobium tepid...
CAB50539    228 avqeiyerlregglpediarevseklsqrgeavikllvpeedenefRAALYTGVAYLFGVMFPITPYFLASss--lTALP 305 Pyrococcus abyss...
NP_622124   225 akeeflnklqdsgipmevgeeiaeklnnneeamtnllteeitenevKSALYTGIAYLVGLVFPVIPYFFISss-slLALA 303 Thermoanaerobact...
YP_023568   218 --------------------------------neskrideykkeanSSALATAISYVIGAVIPILPFVFLYk---yYAII 262 Picrophilus torr...
NP_393546   268 VSIVl---vFVVQGFTNAIVALSVNVgifrmAIRASLLALLAAFITFMVGFSF 317 Thermoplasma acidophilum DSM 1728
NP_343905   298 TSYIva--gLSTFIVGSIIGILSGISpf-kkGIQMASLALLAALGTHGLGYLA 347 Sulfolobus solfataricus P2
NP_377496   291 ISSYii-sgIAIFIVGYLIGLLSSVNpa-kkGVEMLSLGILAAIGTHILGLLA 341 Sulfolobus tokodaii str. 7
ZP_00311827 238 LTIIma--iLIILVFNFYISVAKDLPfk-qrFFEMAGISLGVAVISFIIGHFV 287 Clostridium thermocellum ATCC 27405
NP_559590   240 ASIAvgvmlTFLLTFQSAVYADRDFKf---eFLQTVGLLLGTAFLTYLLGEWL 289 Pyrobaculum aerophilum str. IM2
NP_228307   227 LTLTga--vLIVLLFTFFVSVVKEKDfa-kyFLEMFLLSFGVAGFSFLVGILA 276 Thermotoga maritima MSB8
NP_148184   265 ASVMla--vALISIFVFYSSVINETSfr-reIVENLGVLFGTAAAAYIFGDVL 314 Aeropyrum pernix K1
AAO75266    233 VMLTma--lIIIALFNYYYSVARGESfr-krFTEMAVLSFSVAGISFLIGYAL 282 Bacteroides thetaiotaomicron VPI-5482
NP_661724   236 FAGAf----VVIALFNFYVSVAQGVPfr-srFLEMAGLIVAVSGISFLAGLGI 283 Chlorobium tepidum TLS
CAB50539    306 LSVTla--gLALAIVATSISLISGISir-kkVAEMVVTGLGAAFLSYLFGHLM 355 Pyrococcus abyssi GE5
NP_622124   304 FSVIfa--aIALSIVGTVVSVASESLsikgkITEMVITGLGAAALSYLFGTLV 354 Thermoanaerobacter tengcongensis MB4
YP_023568   263 LSVFlv--aMAQGISNSIISLSMGIAii-knAIRASMLALGAALVTFLIGYMF 312 Picrophilus torridus DSM 9790
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