Conserved Protein Domain Family
ZZ_HERC2
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cd02344: ZZ_HERC2 
Zinc finger, ZZ type. Zinc finger present in HERC2 and related proteins. HERC2 is a potential E3 ubiquitin protein ligase and/or guanine nucleotide exchange factor. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
Links
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Statistics
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PSSM-Id: 239084
Aligned: 4 rows
Threshold Bit Score: 94.188
Created: 30-Mar-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Feature 1:Zinc-binding sites [ion binding site]
Evidence:
  • Comment:6 conserved cysteines and 2 conserved histidines coordinate 2 zinc ions
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1        #  #           #  #     #  #      #   #     
NP_004658 2706 VTCDGCQMFPINGSRFKCRNCDDFDFCETCFKT-KKHntRHTFGRI 2750 human
XP_416878 3042 VTCDGCQMFPINGPRFKCRNCDDFDFCETCFKT-RKHntRHTFGRI 3086 chicken
CAG01384  2469 VRCDGCQMFPINGARFKCRNCDDFDFCENCFKT-RKHnpRHSFGRI 2513 Tetraodon nigroviridis
XP_395007 2409 VSCNSCHLLPISGPRFKCKYCENYNLCENCFYTkRCH--RHGFNRI 2452 honey bee

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